U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C4H8O2
Molecular Weight 88.1051
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DIOXANE

SMILES

C1COCCO1

InChI

InChIKey=RYHBNJHYFVUHQT-UHFFFAOYSA-N
InChI=1S/C4H8O2/c1-2-6-4-3-5-1/h1-4H2

HIDE SMILES / InChI

Molecular Formula C4H8O2
Molecular Weight 88.1051
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Adhesion of corneal epithelial cells to cell adhesion peptide modified pHEMA surfaces.
2001
Effect of crown ethers on structure, stability, activity, and enantioselectivity of subtilisin Carlsberg in organic solvents.
2001 Aug 20
Reversible fixation of carbon dioxide at nickel(0) centers: a route for large organometallic rings, dimers, and tetramers.
2001 Dec 3
Synthesis of polyhydroxysterols (I): synthesis of 24-methylenecholest-4-en-3beta,6beta-diol, a cytotoxic natural hydroxylated sterol.
2001 Jan
Crystallization and preliminary X-ray analysis of human transglutaminase 3 from zymogen to active form.
2001 Jul
Extraction and isolation of lignin for utilization as a standard to determine lignin concentration using the acetyl bromide spectrophotometric method.
2001 Jul
A novel cyclooxygenase-inhibitory stilbenolignan from the seeds of Aiphanes aculeata.
2001 Jul 12
Stereoselective synthesis of 2-alkenylaziridines and 2-alkenylazetidines by palladium-catalyzed intramolecular amination of alpha- and beta-amino allenes.
2001 Jul 13
UV-Fluorescence correlation spectroscopy of 2-aminopurine.
2001 Mar
Photodegradation of 1-(2-chlorobenzoyl)-3-(4-chlorophenyl) urea in different media and toxicity of its reaction products.
2001 May
Inclusion compounds of tetrakis(4-nitrophenyl)methane: C-H...O networks, pseudopolymorphism, and structural transformations.
2001 May 16
Occurrence of 1,4-dioxane in cosmetic raw materials and finished cosmetic products.
2001 May-Jun
1,4-dioxane-fused 4-anilinoquinazoline as inhibitors of epidermal growth factor receptor kinase.
2001 Nov
[Development of aziridination and azetizination reactions of amino allenes using a palladium catalyst].
2001 Oct
Comprehensive study on the chemical structure of dioxane lignin from plantation Eucalyptus globulus wood.
2001 Sep
Macroporous poly(L-lactide) scaffold 1. Preparation of a macroporous scaffold by liquid--liquid phase separation of a PLLA--dioxane--water system.
2002
Enzymatic synthesis of a capsinoid by the acylation of vanillyl alcohol with fatty acid derivatives catalyzed by lipases.
2002 Feb
2,3,6,7-Tetrahydroxy-9,10-dimethyl-9,10-dihydro-9,10-ethanoanthracene bis(1,4-dioxane) solvate.
2002 Feb
Synthesis of alternating polystyrene/poly(ethyleneoxide) branched polymacromonomers.
2002 Jan 18
Fluorescence probe properties of intramolecular charge transfer diphenylbutadienes in micelles and vesicles.
2002 Jun 13
Molecular imprinting of enzymes with water-insoluble ligands for nonaqueous biocatalysis.
2002 May 15
Patents
Substance Class Chemical
Created
by admin
on Fri Dec 15 14:59:33 GMT 2023
Edited
by admin
on Fri Dec 15 14:59:33 GMT 2023
Record UNII
J8A3S10O7S
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DIOXANE
MI  
Systematic Name English
DIOXAN [MART.]
Common Name English
1,4-DIOXANE [USP-RS]
Common Name English
1,4-DIOXANE [IARC]
Common Name English
DIOXANE [MI]
Common Name English
1,4-DIOXANE
HSDB  
Systematic Name English
NSC-8728
Code English
1,4-DIOXANE [HSDB]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C45187
Created by admin on Fri Dec 15 14:59:33 GMT 2023 , Edited by admin on Fri Dec 15 14:59:33 GMT 2023
Code System Code Type Description
DAILYMED
J8A3S10O7S
Created by admin on Fri Dec 15 14:59:33 GMT 2023 , Edited by admin on Fri Dec 15 14:59:33 GMT 2023
PRIMARY
EVMPD
SUB130313
Created by admin on Fri Dec 15 14:59:33 GMT 2023 , Edited by admin on Fri Dec 15 14:59:33 GMT 2023
PRIMARY
HSDB
81
Created by admin on Fri Dec 15 14:59:33 GMT 2023 , Edited by admin on Fri Dec 15 14:59:33 GMT 2023
PRIMARY
RXCUI
2383534
Created by admin on Fri Dec 15 14:59:33 GMT 2023 , Edited by admin on Fri Dec 15 14:59:33 GMT 2023
PRIMARY
RS_ITEM_NUM
1601521
Created by admin on Fri Dec 15 14:59:33 GMT 2023 , Edited by admin on Fri Dec 15 14:59:33 GMT 2023
PRIMARY
WIKIPEDIA
1,4-DIOXANE
Created by admin on Fri Dec 15 14:59:33 GMT 2023 , Edited by admin on Fri Dec 15 14:59:33 GMT 2023
PRIMARY
PUBCHEM
31275
Created by admin on Fri Dec 15 14:59:33 GMT 2023 , Edited by admin on Fri Dec 15 14:59:33 GMT 2023
PRIMARY
CHEBI
46923
Created by admin on Fri Dec 15 14:59:33 GMT 2023 , Edited by admin on Fri Dec 15 14:59:33 GMT 2023
PRIMARY
DRUG BANK
DB03316
Created by admin on Fri Dec 15 14:59:33 GMT 2023 , Edited by admin on Fri Dec 15 14:59:33 GMT 2023
PRIMARY
MERCK INDEX
m4598
Created by admin on Fri Dec 15 14:59:33 GMT 2023 , Edited by admin on Fri Dec 15 14:59:33 GMT 2023
PRIMARY Merck Index
EPA CompTox
DTXSID4020533
Created by admin on Fri Dec 15 14:59:33 GMT 2023 , Edited by admin on Fri Dec 15 14:59:33 GMT 2023
PRIMARY
CHEBI
47032
Created by admin on Fri Dec 15 14:59:33 GMT 2023 , Edited by admin on Fri Dec 15 14:59:33 GMT 2023
PRIMARY
SMS_ID
100000156409
Created by admin on Fri Dec 15 14:59:33 GMT 2023 , Edited by admin on Fri Dec 15 14:59:33 GMT 2023
PRIMARY
ECHA (EC/EINECS)
204-661-8
Created by admin on Fri Dec 15 14:59:33 GMT 2023 , Edited by admin on Fri Dec 15 14:59:33 GMT 2023
PRIMARY
NSC
8728
Created by admin on Fri Dec 15 14:59:33 GMT 2023 , Edited by admin on Fri Dec 15 14:59:33 GMT 2023
PRIMARY
FDA UNII
J8A3S10O7S
Created by admin on Fri Dec 15 14:59:33 GMT 2023 , Edited by admin on Fri Dec 15 14:59:33 GMT 2023
PRIMARY
CAS
123-91-1
Created by admin on Fri Dec 15 14:59:33 GMT 2023 , Edited by admin on Fri Dec 15 14:59:33 GMT 2023
PRIMARY
MESH
C025223
Created by admin on Fri Dec 15 14:59:33 GMT 2023 , Edited by admin on Fri Dec 15 14:59:33 GMT 2023
PRIMARY
NCI_THESAURUS
C44298
Created by admin on Fri Dec 15 14:59:33 GMT 2023 , Edited by admin on Fri Dec 15 14:59:33 GMT 2023
PRIMARY NCIT
Related Record Type Details
METABOLITE -> PARENT
Related Record Type Details
PARENT -> IMPURITY
Limit of Residual Solvents
CHROMATOGRAPHIC PURITY (GC)
USP