Dioxane

Details

Stereochemistry	ACHIRAL
Molecular Formula	C4H8O2
Molecular Weight	88.1051
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

C1COCCO1

InChI

InChIKey=RYHBNJHYFVUHQT-UHFFFAOYSA-N

InChI=1S/C4H8O2/c1-2-6-4-3-5-1/h1-4H2

HIDE SMILES / InChI

Molecular Formula	C4H8O2
Molecular Weight	88.1051
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Physico-chemical studies on the charge-transfer complex formed between sulfadoxine and pyrimethamine with chloranilic acid.	2002-07-20	12093493
A new synthetic route to boron-10 enriched pentaborane(9) from boric acid and its conversion to anti-(10)B(18)H(22).	2002-06-26	12071737
Fluorescence probe properties of intramolecular charge transfer diphenylbutadienes in micelles and vesicles.	2002-06-13	12007623
N,N'-Dithiobisphthalimide-1,4-dioxan (1/0.6): a C2/c solvate with disordered solvent molecules localized in channels.	2002-06	12050438
Crystallization and preliminary diffraction data of BaP1, a haemorrhagic metalloproteinase from Bothrops asper snake venom.	2002-06	12037308
Effect of blending calcium compounds on hydrolytic degradation of poly(DL-lactic acid-co-glycolic acid).	2002-06	12033595
13C-NMR study of 4-azasteroids in solution and solid state.	2002-06	11996935
Electronic effects and the stereochemistries in rearrangement-displacement reactions of triaryl(halomethyl)silanes with fluoride and with alkoxide ions.	2002-05-31	12027666
The rodent carcinogens 1,4-dioxane and thiourea induce meiotic non-disjunction in Drosophila melanogaster females.	2002-05-27	12034324
Optimization of the separation of some Chelidonium maius L. alkaloids by reversed phase high-performance liquid chromatography using cyanopropyl bonded stationary phase.	2002-05-25	12026115
Syntheses of C12,N13 heterocyclic bridged fused indenopyrrolocarbazoles.	2002-05-17	12003530
Molecular imprinting of enzymes with water-insoluble ligands for nonaqueous biocatalysis.	2002-05-15	11996551
Design and synthesis of novel 5-substituted acyclic pyrimidine nucleosides as potent and selective inhibitors of hepatitis B virus.	2002-05-09	11985471
A study of the ionic liquid mediated microwave heating of organic solvents.	2002-05-03	11975584
Improved synthesis and molecular modeling of 4beta,19-dihydroxyandrost-5-en-17-one, an excellent inhibitor of aromatase.	2002-05	12036037
Determination of the retention behavior of barbituric acid derivatives in reversed-phase high-performance liquid chromatography by using quantitative structure-retention relationships.	2002-04-25	12013230
Selective permeation and organic extraction of recombinant green fluorescent protein (gfpuv) from Escherichia coli.	2002-04-24	11972900
Coupling of surface carboxyls of carboxymethylcellulase with aniline via chemical modification: extreme thermostabilization in aqueous and water-miscible organic mixtures.	2002-04-06	11934296
Enzyme activation in organic solvents: co-lyophilization of subtilisin Carlsberg with methyl-beta-cyclodextrin renders an enzyme catalyst more active than the cross-linked enzyme crystals.	2002-04-05	11857281
Collagen stability: insights from NMR spectroscopic and hybrid density functional computational investigations of the effect of electronegative substituents on prolyl ring conformations.	2002-03-20	11890798
Second derivative fluorescence spectra of indole compounds.	2002-03	11872172
Crystallization and X-ray analysis of native and selenomethionyl beta-mannanase Man5A from blue mussel, Mytilus edulis, expressed in Pichia pastoris.	2002-03	11856850
Inclusion behavior of thiacalix[4]arenetetrasulfonate toward water-miscible organic molecules studied by salting-out and X-ray crystallography.	2002-02-21	11843578
Pd(II) acts simultaneously as a Lewis acid and as a transition-metal catalyst: synthesis of cyclic alkenyl ethers from acetylenic aldehydes.	2002-02-06	11817947
New organic superconductors consisting of an unprecedented pi-electron donor.	2002-02-06	11817930
Enzymatic synthesis of a capsinoid by the acylation of vanillyl alcohol with fatty acid derivatives catalyzed by lipases.	2002-02	11999404
2,3,6,7-Tetrahydroxy-9,10-dimethyl-9,10-dihydro-9,10-ethanoanthracene bis(1,4-dioxane) solvate.	2002-02	11828117
Effect of organic solvents on stability and activity of two related alcohol dehydrogenases: a comparative study.	2002-02	11809419
Antifungal sordarins. Synthesis and structure-activity relationships of 3',4'-fused dioxolane and dioxane derivatives.	2002-01-21	11755335
Synthesis of alternating polystyrene/poly(ethyleneoxide) branched polymacromonomers.	2002-01-18	11843159
Solvent effects on the electronic absorption spectra and acid strength of some substituted pyridinols.	2002-01-15	11808729
Synthesis of alpha-lactosyl-(1-->3)-L-glycero-alpha-D-manno-heptopyranoside, a partial oligosaccharide structure expressed within the lipooligosaccharide produced by Neisseria gonorrhoeae strain 15253.	2002-01-07	11755907
Excited state proton transfer reaction of two new intramolecularly hydrogen bonded Schiff bases at room temperature and 77K.	2002-01-01	11808646
Macroporous poly(L-lactide) scaffold 1. Preparation of a macroporous scaffold by liquid--liquid phase separation of a PLLA--dioxane--water system.	2002	11870649
Reversible fixation of carbon dioxide at nickel(0) centers: a route for large organometallic rings, dimers, and tetramers.	2001-12-03	11775695
Quenching of singlet molecular oxygen (1O2) by azide anion in solvent mixtures.	2001-12	11783930
A laser flash photolysis study of curcumin in dioxane-water mixtures.	2001-12	11783928
Synthesis and in vitro antifungal activities of novel triazole antifungal agent CS-758.	2001-12	11767091
Mechanisms of acid-catalyzed Z/E isomerization of imines.	2001-11-30	11722194
Preparation of 1-(3-C-(propa-1,2-dienyl)-D-ribo-pentofuranosyl)uracil, an allenic nucleoside.	2001-11-27	11719991
1,4-dioxane-fused 4-anilinoquinazoline as inhibitors of epidermal growth factor receptor kinase.	2001-11	11822173
Two OPEEs (organic phase enzyme electrodes) used to check the percentage water content in hydrophobic foods and drugs.	2001-11	11763068
Enantioselective ring cleavage of dioxane acetals mediated by a chiral Lewis acid: application to asymmetric desymmetrization of meso-1,3-diols.	2001-10-18	11594821
[Development of aziridination and azetizination reactions of amino allenes using a palladium catalyst].	2001-10	11676175
Fast, efficient and selective deprotection of the tert-butoxycarbonyl (Boc) group using HCl/dioxane (4 m).	2001-10	11606219
Effects of liquid phase composition on salt cluster formation in positive ion mode electrospray mass spectrometry: implications for clustering mechanism in electrospray.	2001-10	11605968
Effect of chronic inhalation of toluene and dioxane on activity of free radical processes in rat ovaries and brain.	2001-09	11740571
Interpretation of the reversible inhibition of adenosine deaminase by small cosolutes in terms of molecular crowding.	2001-08-14	11583161
Crystallization and preliminary X-ray analysis of human transglutaminase 3 from zymogen to active form.	2001-07	11562168
Final report on the safety assessment of PEG-25 propylene glycol stearate, PEG-75 propylene glycol stearate, PEG-120 propylene glycol stearate, PEG-10 propylene glycol, PEG-8 propylene glycol cocoate, and PEG-55 propylene glycol oleate.	2001	11800049

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:34:19 GMT 2025` Edited by `admin` on `Mon Mar 31 17:34:19 GMT 2025`
Record UNII	J8A3S10O7S
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

1,4-DIOXANE

Preferred Name

English

Dioxane

Systematic Name

English

DIOXAN [MART.]

Common Name

English

1,4-DIOXANE [USP-RS]

Common Name

English

1,4-DIOXANE [IARC]

Common Name

English

DIOXANE [MI]

Common Name

English

NSC-8728

Code

English

1,4-DIOXANE [HSDB]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C45187