Approval Year
| Substance Class |
Protein
Created
by
admin
on
Edited
Sat Dec 16 18:56:55 UTC 2023
by
admin
on
Sat Dec 16 18:56:55 UTC 2023
|
| Protein Type | ENZYME |
| Protein Sub Type | |
| Sequence Origin | HUMAN |
| Sequence Type | COMPLETE |
| Record UNII |
5RJT9C7KXH
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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P18405
Created by
admin on Sat Dec 16 18:56:56 UTC 2023 , Edited by admin on Sat Dec 16 18:56:56 UTC 2023
|
PRIMARY | |||
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5RJT9C7KXH
Created by
admin on Sat Dec 16 18:56:56 UTC 2023 , Edited by admin on Sat Dec 16 18:56:56 UTC 2023
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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SUBSTRATE->ENZYME |
Km
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET |
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SUBSTRATE -> METABOLIC ENZYME |
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SUBSTRATE->ENZYME |
Km
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INHIBITOR -> TARGET |
As compared to finasteride, dutasteride is 60-fold more potent in its initial Ki versus type 1 5AR and ~5-fold more rapid in inactivating the enzyme
TIME-DEPENDENT INHIBITION
IC50
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INHIBITOR -> TARGET |
IC50
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SUBSTRATE->ENZYME |
Vmax
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SUBSTRATE -> METABOLIC ENZYME |
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SUBSTRATE->ENZYME |
Vmax
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SUBSTRATE->ENZYME |
Km
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WEAK INHIBITOR->TARGET |
IC50
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SUBSTRATE->ENZYME |
Vmax
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| Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
|---|---|---|---|---|---|---|
| MOL_WEIGHT:NUMBER(CALCULATED) | CHEMICAL |
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| Molecular Formula | CHEMICAL |
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