U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 21 - 30 of 574 results

Status:
US Approved OTC
Source:
21 CFR 349.12(d)(5) ophthalmic:demulcents propylene glycol
Source URL:
First approved in 1961
Source:
VOSOL PROPYLENE GLYCOL by WAMPOLE LABS
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)


PROPYLENE GLYCOL is a component of SYSTANE® Lubricant. It is used for the temporary relief of burning and irritation due to dryness of the eye.
Status:
US Approved OTC
Source:
21 CFR 358.710(a)(7) dandruff:dandruff sulfur
Source URL:
First marketed in 1921
Source:
Washed Sulphur U.S.P.
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


Mercury(I) iodide is a chemical compound that has been used as a drug in the 19th century, sometimes under the contemporary name of 'protiodide of mercury'. Mercury(I) iodide was used to treat a wide range of conditions; everything from acne to kidney disease and in particular was the treatment of choice for syphilis. It was available over the counter at any drugstore in the world, the most common form being a concoction of protiodide, licorice, glycerin, and marshmallow. Taken orally, and in low doses, protiodide causes excessive salivation, fetid breath, spongy and bleeding gums, and sore teeth. Excessive use or an overdose causes physical weakness, loss of teeth, hemolysing (destruction of the red blood cells) of the blood and necrosis of the bones and tissues of the body. Early signs of an overdose or excessive use are muscular tremors, chorea, and locomotor ataxia. Violent bloody vomiting and voiding also occur.
Status:
Investigational
Source:
INN:sprodiamide [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Sprodiamide is a nonionic paramagnetic dysprosium chelate agent patented by Salutar, Inc.as diagnostic imaging contrast media. Compare with gadolinium-based agents Sprodiamide shows a stronger T2 effect and negligible T1 effect. This property makes Sprodiamide useful for blood volume imaging. In a preclinical model of reperfused ischemia of the rat intestine administration of Sprodiamide improved the contrast between the normal and ischemic intestine on T2-weighted images, and administration of both gadodiamide and Sprodiamide improved the contrast on T1- and T2-weighted images.
Status:
Investigational
Source:
INN:pararosaniline embonate [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Pararosaniline pamoate (CI 403-A) was developed as an orally active drug for the treatment of Schistosoma japonicum infection. The clinical trial has shown that capsules were safe and effective; in addition, this drug was well tolerated with a minimum of side effects, which were mostly mild and transient and did not require interruption of treatment. Besides, pararosaniline pamoate was an inhibitor of E.histolytica Hsp90 (EhHsp90) with promising activity against the parasite Pararosaniline pamoate, that causes amebiasis worldwide. Information about the current use of this drug is not available.
Status:
Investigational
Source:
INN:ioxabrolic acid
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Ioxabrolic Acid is triiodobenzoic acid derivative and iodine-containing contrast media
Status:
Investigational
Source:
INN:iomorinic acid
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Iomorinic Acid is triiodobenzamide derivative patented by Lentia G.m.b.H. as a radiographic contrast medium for liver imaging.
Status:
Investigational
Source:
INN:perflisobutane [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Perflisobutane is an anesthetic agent.
Status:
Investigational
Source:
INN:pyrimitate
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Pyrimitate is a pyrimidinyl thiophosphate derivative patented by Imperial Chemical Industries Ltd. as an insecticide and acaricide
Status:
Investigational
Source:
INN:ethyl cartrizoate
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Ethyl cartrizoate has been used in diagnostics as a bronchographic agent.
Status:
Investigational
Source:
INN:benoxafos
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Benoxafos was used as an insecticide agent.