U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 241 - 250 of 3565 results

Status:
Investigational
Source:
INN:rifamexil
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Rifamexil (also known as MDL 62769 or P/DEA) is a derivative of rifamycin (a natural antibiotic produced by Amycolatopsis rifamycinica). This drug has greater intrinsic activity against Myobacterium avium (MAC) than rifampin. Information on current use of this compound is not available.
Status:
Investigational
Source:
INN:nisbuterol
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Nisbuterol, a nicotinic acid ester, is a bronchodilator.
Status:
Investigational
Source:
INN:salmisteine
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Salmisteine was studied as an antipyretic and mucolytic agent. Information about the current use of this compound is not available.
Status:
Investigational
Source:
INN:oxabrexine
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Oxabrexine was developed as a diuretic; however, this compound has never been marketed. Information about the current use of this compound is not available.
Status:
Investigational
Source:
Acta Endocrinol (Copenh). 1966;53:Suppl 111:3-26.: Not Applicable Human clinical trial Completed Menstruation Disturbances
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)


Conditions:

Pregnanediol is a chief steroid metabolite of progesterone that is biologically inactive and occurs as pregnanediol glucuronate in the urine. Pregnanediol has two hydroxyl groups, at 3-alpha and 20-alpha. A test can be done to measure the amount of pregnanediol in urine. The urine test offers an indirect way to measure progesterone levels in the body. It is a standard in the colorimetric determination of urinary pregnanediol in clinical laboratories.
Status:
Investigational
Source:
INN:clentiazem
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Clentiazem is a chloride derivative of diltiazem, originated in Tanabe Seiyaku. It works as a blocker of calcium channels. The drug was investigated in the clinical trials for the treatment of stable angina, and essential hypertension. Despite the positive results of clinical trials, no development of the drug was reported.
Status:
Investigational
Source:
INN:pyrrolifene [INN]
Source URL:

Class (Stereo):
CHEMICAL (UNKNOWN)

Pyrroliphene is a dialkylaminodiphenylbutanol ester with antitussive and analgesic activities. In clinical trials the major side effect of Pyrroliphene was sedation, and the other side effect liabilities were similar to those of morphine.
Status:
Investigational
Source:
INN:cicortonide
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Cicortonide is a synthetic cyano-glucocorticoid with anti-inflammatory and antirheumatic, as well as antiallergenic properties.
Status:
Investigational
Source:
INN:mespirenone
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Mespirenone (ZK 94679, 15β,16β-methylene-spironolactone) is a steroid aldosterone antagonist. In addition, it is a quite specific inhibitor of adrenocortical mineralocorticoid synthesis. In rodents mespirenone effectively prevents aldosterone-induced hypertension. It exerts natriuretic efficacy. Although it reached phase II clinical trials, it was discontinued in 1989.
Status:
Investigational
Source:
INN:diacetamate [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Diacetamate (Acetaminophen Acetate, Acetaminophen Impurity, diacetyl-p-aminophenol) is a acetaminophen synthetic impurity. Acetaminophen-aspirin mixtures have lower stability due to acetylation of the former by the latter, producing diacetyl-p-aminophenol.