PYRROLIPHENE

Details

Stereochemistry	UNKNOWN
Molecular Formula	C23H29NO2
Molecular Weight	351.4819
Optical Activity	UNSPECIFIED
Defined Stereocenters	0 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(CN1CCCC1)C(CC2=CC=CC=C2)(OC(C)=O)C3=CC=CC=C3

InChI

InChIKey=XPSOFSIDLMRECY-UHFFFAOYSA-N

InChI=1S/C23H29NO2/c1-19(18-24-15-9-10-16-24)23(26-20(2)25,22-13-7-4-8-14-22)17-21-11-5-3-6-12-21/h3-8,11-14,19H,9-10,15-18H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C23H29NO2
Molecular Weight	351.4819
Charge	0
Count

Stereochemistry	MIXED
Additional Stereochemistry	No
Defined Stereocenters	0 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/15714600 | https://linkinghub.elsevier.com/retrieve/pii/S0022354915339332 | https://www.ncbi.nlm.nih.gov/pubmed/4919646

Pyrroliphene is a dialkylaminodiphenylbutanol ester with antitussive and analgesic activities. In clinical trials the major side effect of Pyrroliphene was sedation, and the other side effect liabilities were similar to those of morphine.

Originator

Approval Year

PubMed

Title	Date	PubMed
Simultaneous determination of paracetamol and dextropropoxyphene in human plasma by liquid chromatography/tandem mass spectrometry: application to clinical bioequivalence studies.	2005	15714600

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:12:54 GMT 2023` Edited by `admin` on `Fri Dec 15 16:12:54 GMT 2023`
Record UNII	T5Q0WA2589
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PYRROLIPHENE

Common Name

English

(+)-.ALPHA.-BENZYL-.BETA.-METHYL-.ALPHA.-PHENYL-1-PYRROLIDINEPROPANOL ACETATE (ESTER)

Common Name

English

pyrrolifene [INN]

Common Name

English

1-PYRROLIDINEPROPANOL, .BETA.-METHYL-.ALPHA.-PHENYL-.ALPHA.-(PHENYLMETHYL)-, ACETATE (ESTER)

Common Name

English

PYRROLIFENE

Official Name

English

Classification Tree Code System Code

NCI_THESAURUS

C241