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Details

Stereochemistry ACHIRAL
Molecular Formula C10H11NO3
Molecular Weight 193.1996
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DIACETAMATE

SMILES

CC(=Nc1ccc(cc1)OC(=O)C)O

InChI

InChIKey=UJAOSPFULOFZRR-UHFFFAOYSA-N
InChI=1S/C10H11NO3/c1-7(12)11-9-3-5-10(6-4-9)14-8(2)13/h3-6H,1-2H3,(H,11,12)

HIDE SMILES / InChI

Molecular Formula C10H11NO3
Molecular Weight 193.1996
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Diacetamate (Acetaminophen Acetate, Acetaminophen Impurity, diacetyl-p-aminophenol) is a acetaminophen synthetic impurity. Acetaminophen-aspirin mixtures have lower stability due to acetylation of the former by the latter, producing diacetyl-p-aminophenol.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
PubMed

PubMed

TitleDatePubMed
Crystallization of paracetamol from solution in the presence and absence of impurity.
2001 Mar 14
Microhardness and dislocation identification studies on paracetamol single crystals.
2001 May
Solubility prediction in supercritical CO(2) using minimum number of experiments.
2002 May
Dissolution kinetics of paracetamol single crystals.
2002 May 15
Solid-state characterization of nevirapine.
2008 Sep
Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Sat Jun 26 02:26:41 UTC 2021
Edited
by admin
on Sat Jun 26 02:26:41 UTC 2021
Record UNII
BFG1TY61BG
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DIACETAMATE
INN  
INN  
Official Name English
ACETAMINOPHEN RELATED COMPOUND A
USP-RS  
Common Name English
DIACETAMATE [INN]
Common Name English
ACETAMINOPHEN RELATED COMPOUND A [USP-RS]
Common Name English
NSC-6083
Code English
PARACETAMOL IMPURITY H [EP]
Common Name English
NSC-33893
Code English
4-ACETAMIDOPHENYL ACETATE
Systematic Name English
N,O-DIACETYL-4-AMINOPHENO
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C241
Created by admin on Sat Jun 26 02:26:41 UTC 2021 , Edited by admin on Sat Jun 26 02:26:41 UTC 2021
Code System Code Type Description
NCI_THESAURUS
C77313
Created by admin on Sat Jun 26 02:26:41 UTC 2021 , Edited by admin on Sat Jun 26 02:26:41 UTC 2021
PRIMARY
EVMPD
SUB07061MIG
Created by admin on Sat Jun 26 02:26:41 UTC 2021 , Edited by admin on Sat Jun 26 02:26:41 UTC 2021
PRIMARY
CAS
2623-33-8
Created by admin on Sat Jun 26 02:26:41 UTC 2021 , Edited by admin on Sat Jun 26 02:26:41 UTC 2021
PRIMARY
FDA UNII
BFG1TY61BG
Created by admin on Sat Jun 26 02:26:41 UTC 2021 , Edited by admin on Sat Jun 26 02:26:41 UTC 2021
PRIMARY
USP_CATALOG
1003010
Created by admin on Sat Jun 26 02:26:41 UTC 2021 , Edited by admin on Sat Jun 26 02:26:41 UTC 2021
PRIMARY USP-RS
INN
2488
Created by admin on Sat Jun 26 02:26:41 UTC 2021 , Edited by admin on Sat Jun 26 02:26:41 UTC 2021
PRIMARY
MESH
C029014
Created by admin on Sat Jun 26 02:26:41 UTC 2021 , Edited by admin on Sat Jun 26 02:26:41 UTC 2021
PRIMARY
ECHA (EC/EINECS)
220-077-6
Created by admin on Sat Jun 26 02:26:41 UTC 2021 , Edited by admin on Sat Jun 26 02:26:41 UTC 2021
PRIMARY
ChEMBL
CHEMBL2106185
Created by admin on Sat Jun 26 02:26:41 UTC 2021 , Edited by admin on Sat Jun 26 02:26:41 UTC 2021
PRIMARY
EPA CompTox
2623-33-8
Created by admin on Sat Jun 26 02:26:41 UTC 2021 , Edited by admin on Sat Jun 26 02:26:41 UTC 2021
PRIMARY
PUBCHEM
17499
Created by admin on Sat Jun 26 02:26:41 UTC 2021 , Edited by admin on Sat Jun 26 02:26:41 UTC 2021
PRIMARY
Related Record Type Details
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Related Record Type Details
ACTIVE MOIETY