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Search results for "clozapine" in Related Substance Name (exact match)
Status:
Investigational
Source:
NCT03333824: Phase 1 Interventional Completed Solid Tumours
(2017)
Source URL:
Class:
PROTEIN
Status:
Possibly Marketed Outside US
Source:
NCT00915733: Phase 4 Interventional Completed Myocardial Infarction
(2009)
Source URL:
Class:
PROTEIN
Status:
US Approved Rx
(2002)
Source:
ANDA075713
(2002)
Source URL:
First approved in 1989
Source:
NDA019758
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Clozapine was discovered in 1958 by an anesthetist and now it is used for the treatment of schizophrenia. Although the exact mechanism of its action is unknown, the effect of clozapine on schizophrenia is associated with inhibition of dopamine D2 and serotonin 2A receptors.
