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Restrict the search for
dapsone
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Status:
US Previously Marketed
Source:
LAMPRENE by NOVARTIS
(1986)
Source URL:
First approved in 1986
Source:
LAMPRENE by NOVARTIS
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Clofazimine (Lamprene®) is a fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine (Lamprene®) exerts a slow bactericidal effect on Mycobacterium leprae (Hansen’s bacillus). It inhibits mycobacterial growth and binds preferentially to mycobacterial DNA. It also exerts anti-inflammatory properties in controlling erythema nodosum leprosum reactions. However, its precise mechanisms of action are unknown.
Status:
US Previously Marketed
Source:
DIASONE SODIUM by ABBVIE
(1947)
Source URL:
First approved in 1947
Source:
DIASONE SODIUM by ABBVIE
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Sulfoxone is a water-soluble sulfone and is a competitive inhibitor of the bacterial enzyme dihydropteroate synthetase. Sulfoxone under the brand name Diasone was used as an antileprosy drug, for treatment of dermatitis herpetiformis, and to treat pulmonary tuberculosis. Presently, usage of diasone has been discontinued.
Status:
Possibly Marketed Outside US
Source:
ANDA202230
(1995)
Source URL:
First approved in 1995
Source:
ANDA202230
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Methyl chloride, also called chloromethane, mainly is used as a refrigerant. It’s known, that methyl chloride permeates through human epidermis when exposed at high atmospheric concentrations within relatively short timeframes. Recently published article has shown that chlorinated methyl group could be formed in humans, that might be an important target compound in future medical diagnostic programs.
Status:
Investigational
Source:
NCT03333824: Phase 1 Interventional Completed Solid Tumours
(2017)
Source URL:
Class:
PROTEIN
Status:
Possibly Marketed Outside US
First approved in 2015
Source:
21 CFR 355
Source URL:
Class:
PROTEIN
Status:
US Approved Rx
(2009)
Source:
ANDA078649
(2009)
Source URL:
First approved in 1941
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Sulfacetamide is a synthetic sulfonamide antibiotic, which exerts its effect through inhibition of bacterial dihydrofolate synthetase, an enzyme responsible for the conversion of p-aminobenzoic acid into folic acid in bacterias. The topical formulation of the drug is prescribed for the treatment of acne vulgaris and the ophtalmic formulation is used in patients with eye infections.
Status:
US Previously Marketed
Source:
DIASONE SODIUM by ABBVIE
(1947)
Source URL:
First approved in 1947
Source:
DIASONE SODIUM by ABBVIE
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Sulfoxone is a water-soluble sulfone and is a competitive inhibitor of the bacterial enzyme dihydropteroate synthetase. Sulfoxone under the brand name Diasone was used as an antileprosy drug, for treatment of dermatitis herpetiformis, and to treat pulmonary tuberculosis. Presently, usage of diasone has been discontinued.
