U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 1791 - 1800 of 4227 results

Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)

Methanesulfonic acid is an alkane sulfonic acid in which the alkyl group directly linked to the sulfo- functionality is methyl. Salts and esters of methanesulfonic acid are known as mesylates (or methanesulfonates, as in ethyl methanesulfonate). Methanesulfonic acid is used as an acid catalyst in organic reactions because it is a non-volatile, strong acid that is soluble in organic solvents. Methanesulfonic acid is convenient for industrial applications because it is liquid at ambient temperature. Methanesulfonic acid is also a primary ingredient in rust and scale removers. It is used to clean off surface rust from ceramic, tiles and porcelain which are usually susceptible to acid attack.
Status:
Possibly Marketed Outside US
Source:
Japan:Diisopropylamine Dichloroacetate
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)



Diisopropylamine (DIPA) is a secondary amine, which is used as a chemical intermediate, and catalyst for the synthesis of pesticides and pharmaceuticals. DIPA is primarily used as a precursor for the herbicides dilate and triallate, as well as certain sulfenamides used in the vulcanization of rubber. It is used for adjusting pH in cosmetic formulations, in colognes, and toilet cleaners. It is associated with tobacco either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products. When given intravenously to hypertensive patients, DIPA is known as an antihypertensive agent. DIPA exerts its action by lowering arterial blood pressure, reduction of stroke volume and cardiac output. DIPA reduced blood glucose concentrations in fasted mice and in fasted, glucose-loaded, or streptozotocin-diabetic rats. DADA (diisopropylamine dichloroacetate) was identified as an active domain of pangamic acid. DADA is a vasodilator of peripheral and cerebral arterioles. DADA also considered to aid in the detoxification of chemical and metallic metabolites, possibly by the formation of chelate-like compounds whose excretion by the kidneys is facilitated and increased. DADA increases oxygen utilization and cortical glucose uptake.
Status:
Possibly Marketed Outside US
Source:
Canada:ISOPROPYL MYRISTATE
Source URL:
First approved in 2000

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Isopropyl Myristate is a synthetic oil used as an emollient, thickening agent or lubricant in beauty products. Isopropyl Myristate is a popular cosmetic and pharmaceutical ingredient. It is most often used as an additive in aftershaves, shampoos, bath oils, antiperspirants, deodorants, oral hygiene products, and various creams and lotions.
Status:
Possibly Marketed Outside US
Source:
Pro-Collagen Marine Moisture Essence by Acheson & Acheson Ltd.
(2021)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)


Conditions:

LBA (4-O-beta-D-galactopyranosyl-D-gluconic acid) is an aldonic acid obtained from the oxidation of lactose, with high potential applications as an ingredient in foods and pharmaceutical products, because of its antioxidant, chelating and humectant properties.
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)

Stearoxytrimethylsilane is classified as emollient and skin conditioning agent. It is used in a number of cosmetics formulations. It is derived from stearic acid, a fatty acid obtained from animal fat or plants. When derived from animals, it comes from cows, pigs, sheep, and according to Peta, from dogs and cats euthanized in shelters. Stearic acid is used in cosmetics and lubricants. DOWSIL™ 580 Wax (Stearoxytrimethylsilane (and) Stearyl Alcohol) is a soft, solid mixture of stearyl alcohol and stearoxy trimethylsilane. The cosmetic properties of the wax are a result of the silicone moiety. The inclusion of the stearoxy group involves compatibility with organic ingredients. Hair care and skin care products benefit from the property of this wax to facilitate the formation of a very thin film which is neither oily, tacky or too dry.
1,2-Dipalmitoyl-sn-glycero-3-phosphorylglycerol sodium salt (DPPG) is phosphorylglycerol acylated with palmitic acid, that can be used for the preparation of liposomes with negatively charged hydrophilic head groups.
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ABSOLUTE)

1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE is a glycerophosphocholine lipid molecule also known as dioleoyl lecithin. It is considered to be practically insoluble in water and acidic. Formerly, it was used in liposome studies and biological systems research.
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)

Versetamide is a chelating agent. It is a pharmaceutic aid.

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

N,N-Dimethylacetamide (DMA) is a multipurpose reagent which delivers its own H, C, N and O atoms for the synthesis of a variety of compounds under a number of different experimental conditions. N,N-Dimethylacetamide is a water-miscible solvent, FDA approved as excipient and therefore widely used as drug-delivery vehicle. It has been shown that DMA is epigenetically active since it binds bromodomains and inhibits osteoclastogenesis and inflammation. DMA has a potential as an anti-osteoporotic agent via the inhibition of osteoclast mediated bone resorption and enhanced bone regeneration. N,N-Dimethylacetamide is used as a polar solvent in organic synthesis as well as in reactions involving strong bases such as sodium hydroxide. N,N-Dimethylacetamide finds application as a reaction medium in the production of pharmaceuticals, agrochemicals, dyes and plasticizers. It is widely used in polymer industry due to its high solving power for high molecular-weight polymers and synthetic resins. It plays an important role as a catalyst in various reactions viz. cyclization, halogenation, cynidation, alkylation and dehydrogenation and increases the yield of main products. It is also used as an extracting agent for oil and gases, in paint removers, in the production of photo-resist stripping compounds and as booster solvent in coatings.

Showing 1791 - 1800 of 4227 results