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Details

Stereochemistry MIXED
Molecular Formula C38H75O10P
Molecular Weight 722.9699
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 1,2-DIPALMITOYL-SN-GLYCERO-3-(PHOSPHO-RAC-(1-GLYCEROL))

SMILES

CCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(=O)OCC(O)CO)OC(=O)CCCCCCCCCCCCCCC

InChI

InChIKey=BIABMEZBCHDPBV-BEBVUIBBSA-N
InChI=1S/C38H75O10P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-37(41)45-33-36(34-47-49(43,44)46-32-35(40)31-39)48-38(42)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h35-36,39-40H,3-34H2,1-2H3,(H,43,44)/t35?,36-/m1/s1

HIDE SMILES / InChI

Molecular Formula C38H75O10P
Molecular Weight 722.9699
Charge 0
Count
Stereochemistry EPIMERIC
Additional Stereochemistry No
Defined Stereocenters 1 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Description
Curator's Comment: The description was created based on several sources, including https://www.ncbi.nlm.nih.gov/pubmed/11325729 | https://www.ncbi.nlm.nih.gov/pubmed/12460466

1,2-Dipalmitoyl-sn-glycero-3-phosphorylglycerol sodium salt (DPPG) is phosphorylglycerol acylated with palmitic acid, that can be used for the preparation of liposomes with negatively charged hydrophilic head groups.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Inactive ingredient
Unknown

Approved Use

Unknown
Inactive ingredient
Unknown

Approved Use

Unknown
Diagnostic
LUMASON

Approved Use

Lumason is an ultrasound contrast agent indicated for use in patients with suboptimal echocardiograms to opacify the left ventricular chamber and to improve the delineation of the left ventricular endocardial border.

Launch Date

2014
Diagnostic
LUMASON

Approved Use

Lumason is indicated for use with ultrasound of the liver in adult and pediatric patients to characterize focal liver lesions.

Launch Date

2014
Diagnostic
LUMASON

Approved Use

Lumason is indicated for use in ultrasonography of the urinary tract in pediatric patients for the evaluation of suspected or known vesicoureteral reflux.

Launch Date

2014
PubMed

PubMed

TitleDatePubMed
Enhanced Cationic Charge is a Key Factor in Promoting Staphylocidal Activity of α-Melanocyte Stimulating Hormone via Selective Lipid Affinity.
2016 Aug 16
Patents

Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
Samples containing 2.6 mmol of phospholipids (DMPCd54 plus either DMPA or DMPG at a 3:1 molar ratio) dissolved in chloroform/methanol (1:1 v/v) were mixed alone or with a-MSH, also in the same solvent, to give a final phospholipid to peptide molar ratio of 10:1. The mixtures were dried under vacuum for 3 h to remove all traces of the organic solvents. Then, multilamellar vesicles (MLV) were formed in 1.4 ml buffer heated at a temperature ;10°C above the temperature of the gel-to-liquid-crystalline phase transition (Tm) of the mixture and frozen at 280°C, this process being repeated five times. Differential scanning calorimetry was performed in a high-resolution Microcal MC-2 calorimeter (Microcal Inc., Northampton, MA). Differences in the heat capacity between the sample and the reference cell were obtained by raising the temperature at a constant rate of 45°C/h over a temperature range of 5–60°C. The excess heat capacity functions were obtained after baseline subtraction and correction for the instrument time response. Unless otherwise stated, the third scan was used for transition temperature and enthalpy calculation
Substance Class Chemical
Created
by admin
on Fri Dec 15 19:02:22 GMT 2023
Edited
by admin
on Fri Dec 15 19:02:22 GMT 2023
Record UNII
5045XZ24IY
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
1,2-DIPALMITOYL-SN-GLYCERO-3-(PHOSPHO-RAC-(1-GLYCEROL))
II  
Common Name English
DPPG, L-
Common Name English
DPPG, R-
Common Name English
1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHO-RAC-(1-GLYCEROL)
Common Name English
1,2-DIPALMITOYL-SN-GLYCERO-3-(PHOSPHO-RAC-(1-GLYCEROL)) [II]
Common Name English
DIPALMITOYLPHOSPHATIDYLGLYCEROL, L-
Common Name English
Code System Code Type Description
PUBCHEM
11846227
Created by admin on Fri Dec 15 19:02:23 GMT 2023 , Edited by admin on Fri Dec 15 19:02:23 GMT 2023
PRIMARY
CHEBI
85783
Created by admin on Fri Dec 15 19:02:23 GMT 2023 , Edited by admin on Fri Dec 15 19:02:23 GMT 2023
PRIMARY
FDA UNII
5045XZ24IY
Created by admin on Fri Dec 15 19:02:23 GMT 2023 , Edited by admin on Fri Dec 15 19:02:23 GMT 2023
PRIMARY
EPA CompTox
DTXSID30225325
Created by admin on Fri Dec 15 19:02:23 GMT 2023 , Edited by admin on Fri Dec 15 19:02:23 GMT 2023
PRIMARY
RXCUI
1424658
Created by admin on Fri Dec 15 19:02:23 GMT 2023 , Edited by admin on Fri Dec 15 19:02:23 GMT 2023
PRIMARY RxNorm
CAS
74313-95-4
Created by admin on Fri Dec 15 19:02:23 GMT 2023 , Edited by admin on Fri Dec 15 19:02:23 GMT 2023
PRIMARY