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Details

Stereochemistry ACHIRAL
Molecular Formula CH4O3S
Molecular Weight 96.106
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of Methanesulfonic acid

SMILES

CS(O)(=O)=O

InChI

InChIKey=AFVFQIVMOAPDHO-UHFFFAOYSA-N
InChI=1S/CH4O3S/c1-5(2,3)4/h1H3,(H,2,3,4)

HIDE SMILES / InChI

Molecular Formula CH4O3S
Molecular Weight 96.106
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Methanesulfonic acid is an alkane sulfonic acid in which the alkyl group directly linked to the sulfo- functionality is methyl. Salts and esters of methanesulfonic acid are known as mesylates (or methanesulfonates, as in ethyl methanesulfonate). Methanesulfonic acid is used as an acid catalyst in organic reactions because it is a non-volatile, strong acid that is soluble in organic solvents. Methanesulfonic acid is convenient for industrial applications because it is liquid at ambient temperature. Methanesulfonic acid is also a primary ingredient in rust and scale removers. It is used to clean off surface rust from ceramic, tiles and porcelain which are usually susceptible to acid attack.

Approval Year

PubMed

PubMed

TitleDatePubMed
A role for Seven in Absentia Homolog (Siah1a) in metabotropic glutamate receptor signaling.
2001
Modulation of L-type Ca2+ current but not activation of Ca2+ release by the gamma1 subunit of the dihydropyridine receptor of skeletal muscle.
2001
Extracting biological information from DNA arrays: an unexpected link between arginine and methionine metabolism in Bacillus subtilis.
2001
Changes in neuropeptide expression in the trigeminal ganglion following inferior alveolar nerve section in the ferret.
2001
Opposite effects of dexamethasone and ACTH on the adrenal cortex response to ethane dimethanesulphonate (EDS).
2001 Apr
Insulin and glucose administration stimulates Fos expression in neurones of the paraventricular nucleus that project to autonomic preganglionic structures.
2001 Apr
Effects of increased intraocular pressure on rat retinal ganglion cells.
2001 Apr
Projections from the amygdalo-piriform transition area to the amygdaloid complex: a PHA-l study in rat.
2001 Apr 16
The distribution and characterization of NADPH-d/NOS-IR neurons in the rat cuneate nucleus.
2001 Aug 10
Epididymal epithelial cell involution following a single intraperitoneal administration of ethane dimethanesulfonate in the goat (Capra hircus).
2001 Aug 15
Vasomax for the treatment of male erectile dysfunction.
2001 Feb
Noradrenergic projections from the A1 field to the preoptic area in the brain of the ewe and Fos responses to oestrogen in the A1 cells.
2001 Feb
Mimicry of peptide backbone geometry and heteroatomic side-chain functionality: synthesis of enantiopure indolizidin-2-one amino acids possessing alcohol, acid, and azide functional groups.
2001 Feb 23
Bioavailability and pharmacokinetic profile of dihydroergotoxine from a tablet and from an oral solution formulation.
2001 Jan
Phrenic motoneurons receive monosynaptic inputs from the Kölliker-Fuse nucleus: a light- and electron-microscopic study in the rat.
2001 Jan 12
The posterior hypothalamic area: chemoarchitecture and afferent connections.
2001 Jan 19
Testosterone modulates the dendritic architecture of arcuate neuroendocrine neurons in adult male rats.
2001 Jan 26
Early testicular response to intraperitoneal administration of ethane dimethanesulphonate (EDS) in the goat (Capra hircus).
2001 Jan-Apr
Tirilazad mesylate improve water immersion stress induced decrease in erythrocyte deformability in the rats.
2001 Jan-Feb
Origin of the noradrenergic innervation of the superior olivary complex in the rat.
2001 Jun
Local differences in vagal afferent innervation of the rat esophagus are reflected by neurochemical differences at the level of the sensory ganglia and by different brainstem projections.
2001 Jun 18
Neuroprotective effects of pramipexole in young and aged MPTP-treated mice.
2001 Jun 29
A beta-fiber intensity stimulation of chronically constricted median nerve induces c-fos expression in thalamic projection neurons of the cuneate nucleus in rats with behavioral signs of neuropathic pain.
2001 Mar 23
Intracerebroventricular carbachol induces FOS immunoreactivity in lamina terminalis neurons projecting to the supraoptic nucleus.
2001 Mar 23
Identification of unknown degradation products in a new cholesterol-reducing drug by ion-chromatography coupled to mass spectrometry.
2001 Mar 30
Phenotypic inflammation switch in rats shown by calcitonin gene-related peptide immunoreactive dorsal root ganglion neurons innervating the lumbar facet joints.
2001 May 1
Primary sensory neurons with dichotomizing axons projecting to the facet joint and the sciatic nerve in rats.
2001 May 15
Susceptibility to kindling and neuronal connections of the anterior claustrum.
2001 May 15
Neurokinin-1 receptor-immunoreactive neurons of the ventral respiratory group in the rat.
2001 May 28
The DRAG test: an assay for detection of genotoxic damage.
2001 May-Jun
Subsets of gonadotropin-releasing hormone (GnRH) neurons are activated during a steroid-induced luteinizing hormone surge and mating in mice: a combined retrograde tracing double immunohistochemical study.
2001 Nov 9
Tyrosine kinase inhibitor imatinib (STI571) as an anticancer agent for solid tumours.
2001 Oct
Replacement of surgical castration by GnRH-inhibition or Leydig cell ablation in the male rat Hershberger antiandrogen assay.
2001 Oct
A sequential protocol combining dual neuroanatomical tract-tracing with the visualization of local circuit neurons within the striatum.
2001 Oct 15
Lipase-mediated resolution of 4-TMS-3-butyn-2-ol and use of the mesylate derivatives as a precursor to a highly stereoselective chiral allenylindium reagent.
2001 Oct 18
Characterization of the central nervous system innervation of the rat spleen using viral transneuronal tracing.
2001 Oct 8
Application of an automated synthesis suite to parallel solution-phase peptide synthesis.
2001 Sep
Mu-opioid receptors in the ventral tegmental area are targeted to presynaptically and directly modulate mesocortical projection neurons.
2001 Sep 1
The deep mesencephalic nucleus as an output center of basal ganglia: morphological and electrophysiological similarities with the substantia nigra.
2001 Sep 10
Transneuronal tracing from sympathectomized lumbar epaxial muscle in female rats.
2001 Sep 15
Expression of amphiphysin I in Sertoli cells and its implication in spermatogenesis.
2001 Sep 28
Number, origins, and chemical types of rat pallidostriatal projection neurons.
2001 Sep 3
Patents
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:03:05 GMT 2023
Edited
by admin
on Fri Dec 15 15:03:05 GMT 2023
Record UNII
12EH9M7279
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Methanesulfonic acid
HSDB   II   MI  
Systematic Name English
MESYLATE
Common Name English
NSC-3718
Code English
J1.465F
Code English
METHYLSULFONIC ACID
Systematic Name English
METHANESULPHONIC ACID
Systematic Name English
MESYLIC ACID
Systematic Name English
SULFOMETHANE
Systematic Name English
METHANESULFONIC ACID [MI]
Common Name English
METHANESULFONIC ACID [HSDB]
Common Name English
METHANESULFONIC ACID [II]
Common Name English
Code System Code Type Description
MESH
C045880
Created by admin on Fri Dec 15 15:03:05 GMT 2023 , Edited by admin on Fri Dec 15 15:03:05 GMT 2023
PRIMARY
CAS
75-75-2
Created by admin on Fri Dec 15 15:03:05 GMT 2023 , Edited by admin on Fri Dec 15 15:03:05 GMT 2023
PRIMARY
RXCUI
1426388
Created by admin on Fri Dec 15 15:03:05 GMT 2023 , Edited by admin on Fri Dec 15 15:03:05 GMT 2023
ALTERNATIVE
FDA UNII
12EH9M7279
Created by admin on Fri Dec 15 15:03:05 GMT 2023 , Edited by admin on Fri Dec 15 15:03:05 GMT 2023
PRIMARY
WIKIPEDIA
METHANESULFONIC ACID
Created by admin on Fri Dec 15 15:03:05 GMT 2023 , Edited by admin on Fri Dec 15 15:03:05 GMT 2023
PRIMARY
NSC
3718
Created by admin on Fri Dec 15 15:03:05 GMT 2023 , Edited by admin on Fri Dec 15 15:03:05 GMT 2023
PRIMARY
EVMPD
SUB23071
Created by admin on Fri Dec 15 15:03:05 GMT 2023 , Edited by admin on Fri Dec 15 15:03:05 GMT 2023
PRIMARY
DAILYMED
12EH9M7279
Created by admin on Fri Dec 15 15:03:05 GMT 2023 , Edited by admin on Fri Dec 15 15:03:05 GMT 2023
PRIMARY
PUBCHEM
6395
Created by admin on Fri Dec 15 15:03:05 GMT 2023 , Edited by admin on Fri Dec 15 15:03:05 GMT 2023
PRIMARY
EPA CompTox
DTXSID4026422
Created by admin on Fri Dec 15 15:03:05 GMT 2023 , Edited by admin on Fri Dec 15 15:03:05 GMT 2023
PRIMARY
RXCUI
1426387
Created by admin on Fri Dec 15 15:03:05 GMT 2023 , Edited by admin on Fri Dec 15 15:03:05 GMT 2023
PRIMARY RxNorm
CHEBI
25224
Created by admin on Fri Dec 15 15:03:05 GMT 2023 , Edited by admin on Fri Dec 15 15:03:05 GMT 2023
PRIMARY
ECHA (EC/EINECS)
200-898-6
Created by admin on Fri Dec 15 15:03:05 GMT 2023 , Edited by admin on Fri Dec 15 15:03:05 GMT 2023
PRIMARY
SMS_ID
100000088617
Created by admin on Fri Dec 15 15:03:05 GMT 2023 , Edited by admin on Fri Dec 15 15:03:05 GMT 2023
PRIMARY
CHEBI
27376
Created by admin on Fri Dec 15 15:03:05 GMT 2023 , Edited by admin on Fri Dec 15 15:03:05 GMT 2023
PRIMARY
MERCK INDEX
m7296
Created by admin on Fri Dec 15 15:03:05 GMT 2023 , Edited by admin on Fri Dec 15 15:03:05 GMT 2023
PRIMARY Merck Index
NCI_THESAURUS
C45678
Created by admin on Fri Dec 15 15:03:05 GMT 2023 , Edited by admin on Fri Dec 15 15:03:05 GMT 2023
CONCEPT Industrial Aid
NCI_THESAURUS
C75648
Created by admin on Fri Dec 15 15:03:05 GMT 2023 , Edited by admin on Fri Dec 15 15:03:05 GMT 2023
PRIMARY
HSDB
5004
Created by admin on Fri Dec 15 15:03:05 GMT 2023 , Edited by admin on Fri Dec 15 15:03:05 GMT 2023
PRIMARY
Related Record Type Details
SALT/SOLVATE -> PARENT
Related Record Type Details
PARENT -> IMPURITY
Related Record Type Details
ACTIVE MOIETY