METHANESULFONIC ACID

Details

Stereochemistry	ACHIRAL
Molecular Formula	CH4O3S
Molecular Weight	96.106
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CS(O)(=O)=O

InChI

InChIKey=AFVFQIVMOAPDHO-UHFFFAOYSA-N

InChI=1S/CH4O3S/c1-5(2,3)4/h1H3,(H,2,3,4)

HIDE SMILES / InChI

Molecular Formula	CH4O3S
Molecular Weight	96.106
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/30662741 | https://www.ncbi.nlm.nih.gov/pubmed/28675589 | https://www.ncbi.nlm.nih.gov/pubmed/28117992 | https://www.ncbi.nlm.nih.gov/pubmed/30898928

Methanesulfonic acid is an alkane sulfonic acid in which the alkyl group directly linked to the sulfo- functionality is methyl. Salts and esters of methanesulfonic acid are known as mesylates (or methanesulfonates, as in ethyl methanesulfonate). Methanesulfonic acid is used as an acid catalyst in organic reactions because it is a non-volatile, strong acid that is soluble in organic solvents. Methanesulfonic acid is convenient for industrial applications because it is liquid at ambient temperature. Methanesulfonic acid is also a primary ingredient in rust and scale removers. It is used to clean off surface rust from ceramic, tiles and porcelain which are usually susceptible to acid attack.

Approval Year

PubMed

Title	Date	PubMed
Effect of peripheral nerve injury on dorsal root ganglion neurons in the C57 BL/6J mouse: marked changes both in cell numbers and neuropeptide expression.	2001	11483316
Extracting biological information from DNA arrays: an unexpected link between arginine and methionine metabolism in Bacillus subtilis.	2001	11423008
Changes in neuropeptide expression in the trigeminal ganglion following inferior alveolar nerve section in the ferret.	2001	11226702
Catecholamines play a role in the production of interleukin-6 and interleukin-1alpha in unburned skin after burn injury in mice.	2001 Apr	11373471
Opposite effects of dexamethasone and ACTH on the adrenal cortex response to ethane dimethanesulphonate (EDS).	2001 Apr	11370731
Early Neurodegeneration after Hypoxia-Ischemia in Neonatal Rat Is Necrosis while Delayed Neuronal Death Is Apoptosis.	2001 Apr	11300718
Effects of increased intraocular pressure on rat retinal ganglion cells.	2001 Apr	11255034
Projections from the amygdalo-piriform transition area to the amygdaloid complex: a PHA-l study in rat.	2001 Apr 16	11268008
Structural characterization of phosphorylated chitosan and their applications as effective additives of calcium phosphate cements.	2001 Aug	11456064
The distribution and characterization of NADPH-d/NOS-IR neurons in the rat cuneate nucleus.	2001 Aug 10	11489252
Epididymal epithelial cell involution following a single intraperitoneal administration of ethane dimethanesulfonate in the goat (Capra hircus).	2001 Aug 15	11509023
Noradrenergic projections from the A1 field to the preoptic area in the brain of the ewe and Fos responses to oestrogen in the A1 cells.	2001 Feb	11168838
Apoptosis related gene products in differentiated and tumorigenic rat Leydig cells and following regression induced by the cytotoxin ethane dimethanesulphonate.	2001 Feb	11168651
Selective inhibition of human mast cell tryptase by gabexate mesylate, an antiproteinase drug.	2001 Feb 1	11172730
Differential regulation of trkA and p75 in noradrenergic pelvic autonomic ganglion cells after deafferentation of their cholinergic neighbours.	2001 Jan	11168525
Evaluation of muscle re-innervation employing pre- and post-axotomy injections of fluorescent retrograde tracers.	2001 Jan 1	11226720
Vaccination for neuroprotection in the mouse optic nerve: implications for optic neuropathies.	2001 Jan 1	11150329
Expression of brain-derived neurotrophic factor in cortical neurons is regulated by striatal target area.	2001 Jan 1	11150327
Phrenic motoneurons receive monosynaptic inputs from the Kölliker-Fuse nucleus: a light- and electron-microscopic study in the rat.	2001 Jan 12	11150494
Sensory innervation of the cervical facet joints in rats.	2001 Jan 15	11154533
Early testicular response to intraperitoneal administration of ethane dimethanesulphonate (EDS) in the goat (Capra hircus).	2001 Jan-Apr	11686392
Ethanedisulfonate is degraded via sulfoacetaldehyde in Ralstonia sp. strain EDS1.	2001 Jul	11479707
Sulfonate-sulfur metabolism and its regulation in Escherichia coli.	2001 Jul	11479697
Ventral mesopontine projections of the caudomedial shell of the nucleus accumbens and extended amygdala in the rat: double dissociation by organization and development.	2001 Jul 16	11413550
Stereoselective synthesis of chiral 2,3-cis-2-ethynylaziridines by base-mediated intramolecular amination of bromoallenes.	2001 Jul 26	11463293
Modulation of gene expression by androgen and oestrogens in the testis and prostate of the adult rat following androgen withdrawal.	2001 Jun 10	11403897
Local differences in vagal afferent innervation of the rat esophagus are reflected by neurochemical differences at the level of the sensory ganglia and by different brainstem projections.	2001 Jun 18	11370010
Slow-binding inhibition of human prostaglandin endoperoxide synthase-2 with darbufelone, an isoform-selective antiinflammatory di-tert-butyl phenol.	2001 Jun 26	11412128
A beta-fiber intensity stimulation of chronically constricted median nerve induces c-fos expression in thalamic projection neurons of the cuneate nucleus in rats with behavioral signs of neuropathic pain.	2001 Mar 23	11259778
Intracerebroventricular carbachol induces FOS immunoreactivity in lamina terminalis neurons projecting to the supraoptic nucleus.	2001 Mar 23	11259766
Excitotoxic lesions of the rostral thalamic reticular nucleus do not affect the performance of spatial learning and memory tasks in the rat.	2001 May	11182166
Phenotypic inflammation switch in rats shown by calcitonin gene-related peptide immunoreactive dorsal root ganglion neurons innervating the lumbar facet joints.	2001 May 1	11337618
Susceptibility to kindling and neuronal connections of the anterior claustrum.	2001 May 15	11331397
Neurokinin-1 receptor-immunoreactive neurons of the ventral respiratory group in the rat.	2001 May 28	11331521
The DRAG test: an assay for detection of genotoxic damage.	2001 May-Jun	11387020
Role of Cl- current in endothelin-1-induced contraction in rabbit basilar artery.	2001 Nov	11668078
Sex-induced fos in the medial preoptic area: projections to the midbrain.	2001 Oct 8	11568637
Solution-phase automated synthesis of tripeptide derivatives.	2001 Sep	11558600
A novel method for simultaneous anterograde and retrograde labeling of spinal cord motor tracts in the same animal.	2001 Sep	11511680
Distribution of gonadal steroid receptor-containing neurons in the preoptic-periaqueductal gray-brainstem pathway: a potential circuit for the initiation of male sexual behavior.	2001 Sep 17	11536188
Identification of NPY-induced c-Fos expression in hypothalamic neurones projecting to the dorsal vagal complex and the lower thoracic spinal cord.	2001 Sep 24	11550173

Patents

Substance Class	Chemical Created by `admin` on `Wed Jul 05 22:35:12 UTC 2023` Edited by `admin` on `Wed Jul 05 22:35:12 UTC 2023`
Record UNII	12EH9M7279
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

METHANESULFONIC ACID

Systematic Name

English

MESYLATE

Common Name

English

NSC-3718

Code

English

J1.465F

Code

English

METHYLSULFONIC ACID

Systematic Name

English

METHANESULPHONIC ACID

Systematic Name

English

MESYLIC ACID

Systematic Name

English

SULFOMETHANE

Systematic Name

English

METHANESULFONIC ACID [MI]

Common Name

English

METHANESULFONIC ACID [HSDB]

Common Name

English

METHANESULFONIC ACID [II]

Common Name

English

Code System Code Type Description

MESH

C045880