U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 1761 - 1770 of 4227 results

Status:
Possibly Marketed Outside US
Source:
Integra by U.S. Pharmaceutical Corporation
(2009)
Source URL:
First approved in 2009
Source:
Integra by U.S. Pharmaceutical Corporation
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


Status:
Possibly Marketed Outside US
Source:
AcneFree Clear Skin Treatments Advanced Deep Cleansing Duo
Source URL:

Class (Stereo):
CHEMICAL (EPIMERIC)

Conditions:

Metomidate is a non-barbiturate imidazole which produces a sleepy condition of 20-60 minutes duration without substantial analgesia. Since the beginning of 1997 the use of the hypnotic drug metomidate (Hypnodil) in swine is nor longer allowed. This ban caused a substantial therapeutic deficit for anesthesia in swine. 11C-metomidate may be used with positron emission tomography which can differentiate adrenocortical from nonadrenocortical tumors and a suspected adrenocortical cancer may be characterized and staged before surgery. Metomidate hydrochloride is for the sedation and anesthesia of aquarium and non-food fish species. Aquacalm has been granted Indexed status by the FDA for this purpose.
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)

DMDM hydantoin is a preservative in cosmetics and personal care products. It works by slowing and preventing spoilage in products such as shampoos and hair conditioners, and in skin care products like moisturizers and makeup foundations. DMDM hydantoin is also an antimicrobial agent used in cosmetics and personal care products. As an antimicrobial, it can help prevent the growth of fungi, yeast and harmful bacteria that can make people sick or give them rashes, for example. DMDM hydantoin is a “formaldehyde donor,” which means that to work as a preservative and antimicrobial, it releases small levels of formaldehyde throughout the shelf-life of a personal care product or cosmetic product.
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)

Sodium isobutoxide is an alkoxide of isobutanol. It is used in organic chemistry for the synthesis of isobutyl ethers.
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)

Butyl stearate is an ester of stearic acid and butanol. It is used in the cosmetic industry as a plasticizer in nail varnishes, emollient and skin conditioning agent in personal care formulations, as a masking agent in fragrances. In the food industry, it is used as a flavoring agent and as a defoaming agent in processing beet sugar and yeast.
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)

D&C RED NO. 36 1-[(2-chloro-4-nitrophenyl)azo]-2-naphthalenol (CAS Reg. No. 2814-77-9) is a color additive. According to FDA the color additive D&C Red No. 36 may be safely used for coloring ingested drugs, other than mouthwashes and dentifrices, in amounts not to exceed 1.7 milligrams per daily dose of the drug for drugs that are taken continuously only for less than 1 year. For drugs taken continuously for longer than 1 year, the color additive shall not be used in amounts to exceed 1.0 milligram per daily dose of the drug. D&C Red No. 36 may be safely used for coloring externally applied drugs in amounts consistent with current good manufacturing practice. In cosmetics and personal care products, D&C Red No. 36 is a colorant used in the formulation of blushers, lipsticks, face powders, and other makeup products, as well as nail polish and enamels.
Status:
Possibly Marketed Outside US
Source:
NCT02796794: Phase 4 Interventional Unknown status Sepsis
(2015)
Source URL:
First approved in 2007
Source:
Fosteum by Primus Pharmaceuticals, Inc.
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)



GENISTEIN is an isoflavonoid derived from soy products. It inhibits protein-tyrosine kinase and topoisomerase-II (DNA topoisomerases, type II) activity and is used as an antineoplastic and antitumor agent. Experimentally, it has been shown to induce G2 phase arrest in human and murine cell lines. Additionally, genistein has antihelmintic activity. It has been determined to be the active ingredient in Felmingia vestita, which is a plant traditionally used against worms. It has also been demonstrated to be effective against intestinal parasites such as the common liver fluke, pork trematode and poultry cestode. Further, genistein is a phytoestrogen which has selective estrogen receptor modulator properties. It has been investigated in clinical trials as an alternative to classical hormone therapy to help prevent cardiovascular disease in postmenopausal women. Genistein can be found in food sources such as tofu, fava beans, soybeans, kudzu, and lupin. It is also present in certain cell cultures and medicinal plants.

Showing 1761 - 1770 of 4227 results