Cholanic acid is the archetypal C24 bile acid skeleton from which all other C24 bile acids can be derived. Of the two common isomers: 5alpha and 5Beta, the last isomer is the most biologically relevant. 5-Beta Cholanic Acid has been studied as a modulator of the gamma-secretase complex as it pertains to Alzheimer's disease; it has also been identified as an inhibitor of the Ephrin type-A receptor 2 that is involved in cancer cell signaling and angiogenesis.

Tetraisopropyl methylenediphosphonate used in the synthesis of unsaturated phosphonocholines with enantioselective effects on neuronal tumor cell proliferation and viability. Also is used in the preparation of E2-bisphosphonate conjugates as potential anti-osteoporosis agents and in the preparation of AZT 5’-Triphosphate compounds, which display inhibitory effects on HIV-1 reverse transcriptase.