TETRAISOPROPYL METHYLENEDIPHOSPHONATE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C13H30O6P2
Molecular Weight	344.3212
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of TETRAISOPROPYL METHYLENEDIPHOSPHONATE

Structure Search

SMILES

CC(C)OP(=O)(CP(=O)(OC(C)C)OC(C)C)OC(C)C

InChI

InChIKey=ODTQUKVFOLFLIQ-UHFFFAOYSA-N

InChI=1S/C13H30O6P2/c1-10(2)16-20(14,17-11(3)4)9-21(15,18-12(5)6)19-13(7)8/h10-13H,9H2,1-8H3

HIDE SMILES / InChI

Molecular Formula	C13H30O6P2
Molecular Weight	344.3212
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/15115414 | https://www.ncbi.nlm.nih.gov/pubmed/10400344 | https://www.ncbi.nlm.nih.gov/pubmed/15615539

Tetraisopropyl methylenediphosphonate used in the synthesis of unsaturated phosphonocholines with enantioselective effects on neuronal tumor cell proliferation and viability. Also is used in the preparation of E2-bisphosphonate conjugates as potential anti-osteoporosis agents and in the preparation of AZT 5’-Triphosphate compounds, which display inhibitory effects on HIV-1 reverse transcriptase.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2578

PubMed

Title	Date	PubMed
Synthesis and use of novel ether phospholipid enantiomers to probe the molecular basis of the antitumor Effects of alkyllysophospholipids: correlation of differential activation of c-Jun NH(2)-terminal protein kinase with antiproliferative effects in neuronal tumor cells.	2004 May 6	15115414

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Sat Dec 16 08:50:39 GMT 2023` Edited by `admin` on `Sat Dec 16 08:50:39 GMT 2023`
Record UNII	K46Y5V9U61
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TETRAISOPROPYL METHYLENEDIPHOSPHONATE

Systematic Name

English

METHYLENEDIPHOSPHONIC ACID TETRAISOPROPYL ESTER

Systematic Name

English

PHOSPHONIC ACID, METHYLENEDI-, TETRAISOPROPYL ESTER

Systematic Name

English

((DIISOPROPOXYPHOSPHINYL)METHYL)DIISOPROPOXYPHOSPHINE OXIDE

Systematic Name

English

TETRAISOPROPYL METHYLENEBISPHOSPHONATE

Systematic Name

English

NSC-226577

Code

English

PHOSPHONIC ACID, P,P'-METHYLENEBIS-, P,P,P',P'-TETRAKIS(1-METHYLETHYL) ESTER

Systematic Name

English

PHOSPHONIC ACID, METHYLENEBIS-, TETRAKIS(1-METHYLETHYL) ESTER

Systematic Name

English

TETRAKIS(O-ISOPROPYL) METHYLENEDIPHOSPHONATE

Systematic Name

English

Code System Code Type Description

ECHA (EC/EINECS)

216-765-0