Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C16H31BrO2 |
| Molecular Weight | 335.32 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCCCCCCCCCCCCCC(Br)C(O)=O
InChI
InChIKey=DPRAYRYQQAXQPE-UHFFFAOYSA-N
InChI=1S/C16H31BrO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15(17)16(18)19/h15H,2-14H2,1H3,(H,18,19)
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| In Vitro and In Vivo Characterizations of Chiglitazar, a Newly Identified PPAR Pan-Agonist. | 2012 |
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| Chemical genomics profiling of environmental chemical modulation of human nuclear receptors. | 2011-08 |
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| Acyl-protein thioesterase 2 catalyzes the deacylation of peripheral membrane-associated GAP-43. | 2010-11-30 |
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| Palmitate and insulin synergistically induce IL-6 expression in human monocytes. | 2010-11-05 |
|
| Palmitoylation of the S0-S1 linker regulates cell surface expression of voltage- and calcium-activated potassium (BK) channels. | 2010-10-22 |
|
| Palmitoylation of human FasL modulates its cell death-inducing function. | 2010-10-21 |
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| Palmitoylation and function of glial glutamate transporter-1 is reduced in the YAC128 mouse model of Huntington disease. | 2010-10 |
|
| Palmitic acid analogs exhibit nanomolar binding affinity for the HIV-1 CD4 receptor and nanomolar inhibition of gp120-to-CD4 fusion. | 2010-08-13 |
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| Localized fetomaternal hyperglycemia: spatial and kinetic definition by positron emission tomography. | 2010-08-06 |
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| Multiple palmitoyltransferases are required for palmitoylation-dependent regulation of large conductance calcium- and voltage-activated potassium channels. | 2010-07-30 |
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| Eicosapentaenoic acid inhibits endothelial cell migration in vitro. | 2010-07-09 |
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| Interplay of palmitoylation and phosphorylation in the trafficking and localization of phosphodiesterase 10A: implications for the treatment of schizophrenia. | 2010-07-07 |
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| Mice with alopecia, osteoporosis, and systemic amyloidosis due to mutation in Zdhhc13, a gene coding for palmitoyl acyltransferase. | 2010-06-10 |
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| Rapid and selective detection of fatty acylated proteins using omega-alkynyl-fatty acids and click chemistry. | 2010-06 |
|
| Golgi-specific DHHC zinc finger protein GODZ mediates membrane Ca2+ transport. | 2010-02-12 |
|
| Palmitoylation supports the association of tetraspanin CD63 with CD9 and integrin alphaIIbbeta3 in activated platelets. | 2010-02 |
|
| Role of GD3-CLIPR-59 association in lymphoblastoid T cell apoptosis triggered by CD95/Fas. | 2010-01-05 |
|
| Membrane-initiated estradiol signaling increases tyrosine hydroxylase promoter activity with ER alpha in PC12 cells. | 2010-01 |
|
| The C-terminal sequence of RhoB directs protein degradation through an endo-lysosomal pathway. | 2009-12-02 |
|
| Reversible, temperature-dependent supramolecular assembly of aquaporin-4 orthogonal arrays in live cell membranes. | 2009-12-02 |
|
| Molecular mechanism of recombinant liver fatty acid binding protein's antioxidant activity. | 2009-12 |
|
| Role of PSD95 in membrane association and catalytic activity of nNOSalpha in nitrergic varicosities in mice gut. | 2009-10 |
|
| Neuroligin1: a cell adhesion molecule that recruits PSD-95 and NMDA receptors by distinct mechanisms during synaptogenesis. | 2009-05-18 |
|
| Fatty acid acylation regulates trafficking of the unusual Plasmodium falciparum calpain to the nucleolus. | 2009-04 |
|
| The effects of 2-bromopalmitate on the fatty acid composition in differentiating adipocytes of red sea bream (Pagrus major). | 2009-04 |
|
| 2-Bromopalmitate and 2-(2-hydroxy-5-nitro-benzylidene)-benzo[b]thiophen-3-one inhibit DHHC-mediated palmitoylation in vitro. | 2009-02 |
|
| PPAR/RXR Regulation of Fatty Acid Metabolism and Fatty Acid omega-Hydroxylase (CYP4) Isozymes: Implications for Prevention of Lipotoxicity in Fatty Liver Disease. | 2009 |
|
| Protein palmitoylation regulates osteoblast differentiation through BMP-induced osterix expression. | 2009 |
|
| Huntingtin-interacting proteins, HIP14 and HIP14L, mediate dual functions, palmitoyl acyltransferase and Mg2+ transport. | 2008-11-28 |
|
| Molecular characterization of peroxisome proliferator-activated receptors (PPARs) and their gene expression in the differentiating adipocytes of red sea bream Pagrus major. | 2008-11 |
|
| Endogenous peroxisome proliferator-activated receptor-gamma augments fatty acid uptake in oxidative muscle. | 2008-11 |
|
| Mesodermal fate decisions of a stem cell: the Wnt switch. | 2008-09 |
|
| Long chain fatty acid uptake in vivo: comparison of [125I]-BMIPP and [3H]-bromopalmitate. | 2008-08 |
|
| Polyunsaturated fatty acids block platelet-activating factor-induced phosphatidylinositol 3 kinase/Akt-mediated apoptosis in intestinal epithelial cells. | 2008-05 |
|
| Excitotoxic loss of post-synaptic sites is distinct temporally and mechanistically from neuronal death. | 2008-01 |
|
| Palmitoylation of POTE family proteins for plasma membrane targeting. | 2007-11-23 |
|
| R7-binding protein targets the G protein beta 5/R7-regulator of G protein signaling complex to lipid rafts in neuronal cells and brain. | 2007-09-19 |
|
| The role of an intracellular cysteine stretch in the sorting of the type II Na/phosphate cotransporter. | 2007-09 |
|
| Structural and functional analysis of the apoptosis-associated tyrosine kinase (AATYK) family. | 2007-08-24 |
|
| Shuttling of G protein subunits between the plasma membrane and intracellular membranes. | 2007-08-17 |
|
| Mechanisms involved in the cytotoxic and cytoprotective actions of saturated versus monounsaturated long-chain fatty acids in pancreatic beta-cells. | 2007-08 |
|
| Role of LRAT on the retinoid isomerase activity and membrane association of Rpe65. | 2007-07-20 |
|
| Regulation of FAT/CD36 mRNA gene expression by long chain fatty acids in the differentiated 3T3-L1 cells. | 2007-07 |
|
| S-acylation regulates Kv1.5 channel surface expression. | 2007-07 |
|
| Activation of protein phosphatase 2A by palmitate inhibits AMP-activated protein kinase. | 2007-03-30 |
|
| Multiple peroxisome proliferator-activated receptor beta subtypes from Atlantic salmon (Salmo salar). | 2007-03 |
|
| Malonyl coenzyme A affects insulin-stimulated glucose transport in myotubes. | 2007-02 |
|
| Metabolic Functions of Peroxisome Proliferator-Activated Receptor beta/delta in Skeletal Muscle. | 2007 |
|
| Homeostatic plasticity during alcohol exposure promotes enlargement of dendritic spines. | 2006-12 |
|
| Regulation of rat liver apolipoprotein A-I, apolipoprotein A-II and acyl-coenzyme A oxidase gene expression by fibrates and dietary fatty acids. | 1995-08-15 |
Patents
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| Code System | Code | Type | Description | ||
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18263-25-7
Created by
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7EI4G5X28Z
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133152
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82145
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DTXSID0037734
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58378
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242-137-0
Created by
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