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Search results for vitamin root_notes_note in Note (approximate match)
Status:
Possibly Marketed Outside US
Source:
NCT02689999: Phase 4 Interventional Completed Gastroesophageal Reflux Disease (GERD)
(2016)
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Possibly Marketed Outside US
Source:
Thevetin A by SigmaAldrich
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Thevetin A is a steroidal (cardiac) glycoside that has been isolated from the seed kernels. Cardiotonic. It is a Na+-, K+-dependent adenosinetriphosphatase (Na+,K+-ATPase) inhibitor.
Status:
Possibly Marketed Outside US
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
Ristocetin A is an antibiotic, derived from Nocardia lurida and exerts bactericidal effect against a range of Gram-positive cocci, Gramnegative diplococci, and Myco. tuberculosis. Ristocetin A and B were applied to treat staphylococcal infections but no longer used clinically because it caused thrombocytopenia and platelet agglutination. The Von Willebrand Ristocetin Cofactor [vWF:RCo] assay measures the ability of a patient’s plasma to agglutinate platelets in the presence of the antibiotic Ristocetin. The rate of Ristocetin induced agglutination is related to the concentration and functional activity of the plasma von Willebrand factor. Ristocetin is thought to bind to VWF at Glu1239-Pro-Gly Gly1242.
Status:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Aloin is a physiologically active anthraquinone present in aloe. It is a mixture of two diastereomers, termed aloin A (also called barbaloin) and aloin B (or isobarbaloin) which have similar chemical properties. Aloin B is used for research purposes and is not intended for diagnostic or therapeutic use.
Status:
Possibly Marketed Outside US
Source:
Unknown by Egyesult Gyogyszer es Tapszergyar
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Astragaloside A (Astragaloside IV) is the primary pure saponin isolated from Astragalus membranaceus, which has been widely used for the treatment of cardiovascular diseases. Astragaloside IV improves post-ischemic heart function and ameliorated reperfusion arrhythmias accompanied by a significant increase in myocardial antioxidative enzyme superoxide dismutase activity in rat hearts in vitro. While, Astragaloside IV's protective effect on heart function can be partially abrogated by the nitric oxide synthase inhibitor, Nomega-nitro-L-arginine methyl ester. Astrageloside IV has multiple pharmacologic effects, including anti-inflammatory, antifibrotic, antioxidative stress, anti-asthma, antidiabetes, immunoregulation, and cardioprotective effect via numerous signaling pathways. According to the existing studies and clinical practices, Astragaloside A possesses potential for broad application in many diseases.
Status:
Possibly Marketed Outside US
Class (Stereo):
CHEMICAL (ABSOLUTE)
Quinine iodosulfate (herapathite) is a mixed salt of quinine and iodine. Its crystals are dichroic - they function as excellent linear light polarizers absorbing virtually all the light polarized along the shorter axis of the best-developed face. A sheet of quinine iodosulfate sandwiched between two glass plates is called polaroid. Polaroids find applications in areas such as automobile headlights and windscreens, hotel and aircraft windows and sunglasses.
Status:
Possibly Marketed Outside US
Source:
colloidal oatmeal by Central Experimental Farm
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Avenanthramides are a group of phenolic alkaloids found mainly in oats, but also in butterfly eggs (Pieris brassicae and Pieris rapae), and fungal infected carnation (Dianthus caryophyllus). Avenanthramides demonstrate anti-inflammatory, antioxidant, anti-itch, anti-irritant, and antiatherogenic activities. Avenanthramide is considered the active component in a number of skin care products based on colloidal oatmeal; a traditional treatment which was approved by the FDA in 2003. Dietary supplementation with foods enriched in Avenantramides has been studied for the potential to reduce systemic inflammation. Avenanthramides have also been studied in cell models for osteoporosis and cancer.
Status:
Possibly Marketed Outside US
Source:
NCT03130634: Phase 4 Interventional Completed Metastatic Colorectal Cancer
(2016)
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Silymarin, a plant-derived flavonoid from the plant Silybum marianum, is considered the most potential drug to treat almost all kind of liver diseases, particularly alcoholic liver disease, acute and chronic viral hepatitis and toxins-mediated liver dysfunctions. The main component of the silymarin complex is silybin, synonymous with silibinin, sometimes incorrectly called silybinin, which is a mixture of two diastereomers A and B in approximately 1:1 proportion. The drug possess hepatoprotective and antioxidant activity. The hepatoprotective effect is due to stimulation of synthesis of structural and functional proteins and phospholipids, as well as acceleration of the regeneration of hepatocytes. Antioxidant effect is determined by interaction of bioflavones with free radicals in the liver and its detoxication. In such manner the process of peroxidation of the lipids is interrupted and further liver destruction is prevented. Side effect is a mild laxative effect has occasionally been observed.
Status:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
Sennoside B is a member of the class of sennosides that used as the laxative. Sennosides are used all over the world as a treatment for constipation. Sennosides are hydroxyanthracene glycosides derived from Senna leaves. The phytoconstituents principally responsible for its characteristic action are two anthraquinone glycosides namely; Sennoside A and Sennoside B. Sennoside A and B together are responsible for up to 40 – 60% activity of crude senna. They have identical molecular weights and formulae and are in fact diastereomers with the same substituent (H) located in opposite directions. Sennoside B has reported that it has inhibitory effects on PDGF receptor signaling and cell proliferation induced by PDGF-BB in human osteosarcoma cells.
Status:
Possibly Marketed Outside US
Source:
NCT02931136: Phase 4 Interventional Not yet recruiting Mild Cognitive Impairment
(2019)
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Huperzine A is a plant alkaloid derived from Club moss plant, Huperzine serrata, which is a member or the Lycopodium species. Huperzine-A is in phase III clinical trial in the USA (Alzheimer disease) and is available as a dietary supplement. It selectively and reversibly inhibits acetylcholinesterase. Huperzine A is also a NMDA receptor antagonist, which protects the brain against glutamate induced damage, and it increases nerve growth factor levels. Huperzine A is used for Alzheimer's disease, memory and learning enhancement, and age-related memory impairment. It is also used for treating a muscle disease called myasthenia gravis, for increasing alertness and energy, and for protecting against agents that damage the nerves such as nerve gases. It can cause some side effects including nausea, diarrhea, vomiting, sweating, blurred vision, slurred speech, restlessness, loss of appetite, contraction and twitching of muscle fibers, cramping, increased saliva and urine, inability to control urination, high blood pressure, and slowed heart rate. Various medications used for glaucoma, Alzheimer's disease, and other conditions (Cholinergic drugs) interacts with Huperzine A.