Deslorelin is an GnRH agonist used in veterinary. It effects contraception by temporarily suppressing the reproductive endocrine system and preventing production of pituitary (FSH and LH) and gonadal hormones (estradiol and progesterone in females and testosterone in males). The observed effects are similar to those following ovariectomy or castration, but are reversed after the hormone content of the implant is depleted or the implant is removed. As an agonist, deslorelin first stimulates the reproductive system, which can result in estrus and ovulation in females or temporary enhancement of testosterone and semen production in males. Then, down-regulation follows the initial period of stimulation. Although deslorelin can also be an effective contraceptive in males of some species, manufacturer recommends its use primarily in females, since monitoring efficacy in females by suppression of estrous behavior or of gonadal steroids in feces is more straightforward than ensuring continued absence of sperm in males, since most institutions cannot perform regular semen collections. It can, however, be used to ameliorate aggression in males of some species, but higher dosages are usually needed. While the major application of deslorelin was initially male contraception, due to its two differing actions, either the stimulation of oestrus or the sterilization of fertility, its use has been increasing in the bitch as well. SUPRELORIN® F (deslorelin acetate) Implant is a once-yearly, subcutaneous implant that assists in the management of adrenal disease in ferrets.

Barium is a soft, silvery metal that rapidly tarnishes in air and reacts with water. Barium is not an extensively used element. Most is used in drilling fluids for oil and gas wells. It is also used in paint and in glassmaking. All barium compounds are toxic; however, barium sulfate is insoluble and so can be safely swallowed. A suspension of barium sulfate is sometimes given to patients suffering from digestive disorders. This is a ‘barium meal’ or ‘barium enema’. Barium is a heavy element and scatters X-rays, so as it passes through the body the stomach and intestines can be distinguished on an X-ray. Barium carbonate has been used in the past as a rat poison. Barium nitrate gives fireworks a green colour. Barium has no known biological role, although barium sulfate has been found in one particular type of algae. Barium is toxic, as are its water- or acid-soluble compounds. This drug is used as a contrast agent in diagnostic x-ray procedures. Therapeutic advantages of barium sulfate in diagnostic procedures include both its low water solubility and high level of clearance from the body. Barium sulfate is ingested by mouth or administered rectally and combined with granules of effervescent bicarbonate to enhance distension of the GI tract, allowing for enhanced gastrointestinal tract visualization. Barium (E-Z-CAT DRY) is a radiographic contrast agent indicated for use in computed tomography (CT) of the abdomen to delineate the gastrointestinal (GI) tract in adult and pediatric patients. Under physiological conditions, barium sulfate passes through the GI tract in an unchanged form and is absorbed only in pharmacologically insignificant amounts. Common adverse reactions include nausea, vomiting, diarrhea and abdominal cramping.

Silver is a soft metal that is used medically in surgical instruments, dental prostheses, and alloys. According to FDA final rule, all over-the-counter drug products containing colloidal silver ingredients or silver salts for internal or external use are not generally recognized as safe and effective and are misbranded.

Amyl acetate, a banana essence, was used in preparation of penicillin in acid reaction. It’s also an inactive ingredient in Liquid Bandages, which are used to protect cuts and scrapes and to help prevent and protect blisters.