Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | Ag |
| Molecular Weight | 107.8682 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Ag]
InChI
InChIKey=BQCADISMDOOEFD-UHFFFAOYSA-N
InChI=1S/Ag
| Molecular Formula | Ag |
| Molecular Weight | 107.8682 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Silver is a soft metal that is used medically in surgical instruments, dental prostheses, and alloys. According to FDA final rule, all over-the-counter drug products containing colloidal silver ingredients or silver salts for internal or external use are not generally recognized as safe and effective and are misbranded.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Effects of 45-nm silver nanoparticles on coronary endothelial cells and isolated rat aortic rings. | 2009 Dec 15 |
|
| Expression changes of dopaminergic system-related genes in PC12 cells induced by manganese, silver, or copper nanoparticles. | 2009 Nov |
|
| Silver nanoparticles induce cytotoxicity by a Trojan-horse type mechanism. | 2010 Apr |
|
| Silver nanoparticles disrupt GDNF/Fyn kinase signaling in spermatogonial stem cells. | 2010 Aug |
|
| Silver nanoparticles induced heat shock protein 70, oxidative stress and apoptosis in Drosophila melanogaster. | 2010 Feb 1 |
|
| Effects of aqueous exposure to silver nanoparticles of different sizes in rainbow trout. | 2010 Jun |
|
| Evaluation of silver nanoparticle toxicity in skin in vivo and keratinocytes in vitro. | 2010 Mar |
|
| Silver nanoparticle induced blood-brain barrier inflammation and increased permeability in primary rat brain microvessel endothelial cells. | 2010 Nov |
|
| NRF2 Oxidative Stress Induced by Heavy Metals is Cell Type Dependent. | 2011 |
|
| Silver nanoparticles induce apoptosis and G2/M arrest via PKCζ-dependent signaling in A549 lung cells. | 2011 Dec |
|
| Identification, characterization and expression profiles of Chironomus riparius glutathione S-transferase (GST) genes in response to cadmium and silver nanoparticles exposure. | 2011 Feb |
|
| Silver nanoparticles induce oxidative cell damage in human liver cells through inhibition of reduced glutathione and induction of mitochondria-involved apoptosis. | 2011 Feb 25 |
|
| Experimental switching of copper status in laboratory rodents. | 2011 Jan |
|
| The lumenal loop Met672-Pro707 of copper-transporting ATPase ATP7A binds metals and facilitates copper release from the intramembrane sites. | 2011 Jul 29 |
|
| Silver nanoparticles down-regulate Nrf2-mediated 8-oxoguanine DNA glycosylase 1 through inactivation of extracellular regulated kinase and protein kinase B in human Chang liver cells. | 2011 Nov 30 |
|
| Characterization of MtnE, the fifth metallothionein member in Drosophila. | 2011 Oct |
|
| Physicochemical characterization and in vitro hemolysis evaluation of silver nanoparticles. | 2011 Sep |
|
| Cu/Zn- and Mn-superoxide dismutase (SOD) from the copepod Tigriopus japonicus: molecular cloning and expression in response to environmental pollutants. | 2011 Sep |
|
| Vascular tube formation and angiogenesis induced by polyvinylpyrrolidone-coated silver nanoparticles. | 2011 Sep 10 |
|
| Silica nanoparticles and silver-doped silica nanoparticles induce endoplasmatic reticulum stress response and alter cytochrome P4501A activity. | 2012 Apr |
|
| Effects of silver nanoparticles on primary mixed neural cell cultures: uptake, oxidative stress and acute calcium responses. | 2012 Apr |
|
| Exposure to silver nanoparticles inhibits selenoprotein synthesis and the activity of thioredoxin reductase. | 2012 Jan |
|
| Role of the Nrf2-heme oxygenase-1 pathway in silver nanoparticle-mediated cytotoxicity. | 2012 Jan 1 |
|
| Cytotoxic and genotoxic effects of silver nanoparticles in testicular cells. | 2012 Jan 27 |
|
| Silver nanoparticle-induced mutations and oxidative stress in mouse lymphoma cells. | 2012 Jul |
|
| Silver nanoparticles-mediated G2/M cycle arrest of renal epithelial cells is associated with NRF2-GSH signaling. | 2012 Jun 20 |
|
| Toxicogenomic responses of nanotoxicity in Daphnia magna exposed to silver nitrate and coated silver nanoparticles. | 2012 Jun 5 |
|
| [Structure-functional organization of eukaryotic high-affinity copper importer CTR1 determines its ability to transport copper, silver and cisplatin]. | 2012 Mar-Apr |
|
| Distinct immunomodulatory effects of a panel of nanomaterials in human dermal fibroblasts. | 2012 May 5 |
|
| Toxicity of silver nanoparticles to rainbow trout: a toxicogenomic approach. | 2012 Oct |
|
| Cellular uptake, intracellular trafficking and cytotoxicity of silver nanoparticles. | 2012 Sep 3 |
|
| Effects of silver nanoparticles on the liver and hepatocytes in vitro. | 2013 Feb |
|
| Silver nanoparticle-induced cytotoxicity in rat brain endothelial cell culture. | 2013 Feb |
|
| Contributions of rat Ctr1 to the uptake and toxicity of copper and platinum anticancer drugs in dorsal root ganglion neurons. | 2013 Jan 15 |
|
| Non-hepatic tumors change the activity of genes encoding copper trafficking proteins in the liver. | 2013 Jul |
|
| Hypoxia inducible factor-1 (HIF-1)-flavin containing monooxygenase-2 (FMO-2) signaling acts in silver nanoparticles and silver ion toxicity in the nematode, Caenorhabditis elegans. | 2013 Jul 15 |
|
| Silver nanoparticles induce endoplasmatic reticulum stress response in zebrafish. | 2013 Oct 15 |
|
| Investigating oxidative stress and inflammatory responses elicited by silver nanoparticles using high-throughput reporter genes in HepG2 cells: effect of size, surface coating, and intracellular uptake. | 2013 Sep |
|
| The cellular and genomic response of rat dopaminergic neurons (N27) to coated nanosilver. | 2014 Dec |
|
| Silver nanoparticles induce anti-proliferative effects on airway smooth muscle cells. Role of nitric oxide and muscarinic receptor signaling pathway. | 2014 Jan 13 |
|
| Mechanistic study on the biological effects of silver and gold nanoparticles in Caco-2 cells--induction of the Nrf2/HO-1 pathway by high concentrations of silver nanoparticles. | 2014 Jan 3 |
|
| Genotoxicity of silver and titanium dioxide nanoparticles in bone marrow cells of rats in vivo. | 2014 Jan 6 |
|
| Sub-acute intravenous administration of silver nanoparticles in male mice alters Leydig cell function and testosterone levels. | 2014 Jun |
|
| Influence of physicochemical properties of silver nanoparticles on mast cell activation and degranulation. | 2015 Feb |
|
| Evaluation of cytotoxic, oxidative stress, proinflammatory and genotoxic effect of silver nanoparticles in human lung epithelial cells. | 2015 Feb |
|
| Nanotoxicity of silver nanoparticles to red blood cells: size dependent adsorption, uptake, and hemolytic activity. | 2015 Mar 16 |
|
| Silver and titanium dioxide nanoparticles alter oxidative/inflammatory response and renin-angiotensin system in brain. | 2015 Nov |
|
| Cyto- and genotoxic effects of metallic nanoparticles in untransformed human fibroblast. | 2015 Oct |
|
| Silver nanoparticle exposure induces rat motor dysfunction through decrease in expression of calcium channel protein in cerebellum. | 2015 Sep 2 |
|
| Integrative analysis of genes and miRNA alterations in human embryonic stem cells-derived neural cells after exposure to silver nanoparticles. | 2016 May 15 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 16:16:46 UTC 2023
by
admin
on
Fri Dec 15 16:16:46 UTC 2023
|
| Record UNII |
3M4G523W1G
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Official Name | English | ||
|
Common Name | English | ||
|
Official Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Code | English | ||
|
Official Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Code | English | ||
|
Common Name | English | ||
|
Code | English | ||
|
Common Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
|
DSLD |
599 (Number of products:3)
Created by
admin on Fri Dec 15 16:16:47 UTC 2023 , Edited by admin on Fri Dec 15 16:16:47 UTC 2023
|
||
|
CFR |
21 CFR 310.548
Created by
admin on Fri Dec 15 16:16:47 UTC 2023 , Edited by admin on Fri Dec 15 16:16:47 UTC 2023
|
||
|
DSLD |
2291 (Number of products:128)
Created by
admin on Fri Dec 15 16:16:47 UTC 2023 , Edited by admin on Fri Dec 15 16:16:47 UTC 2023
|
||
|
DSLD |
675 (Number of products:6)
Created by
admin on Fri Dec 15 16:16:47 UTC 2023 , Edited by admin on Fri Dec 15 16:16:47 UTC 2023
|
||
|
EPA PESTICIDE CODE |
72599
Created by
admin on Fri Dec 15 16:16:47 UTC 2023 , Edited by admin on Fri Dec 15 16:16:47 UTC 2023
|
||
|
EPA PESTICIDE CODE |
72501
Created by
admin on Fri Dec 15 16:16:47 UTC 2023 , Edited by admin on Fri Dec 15 16:16:47 UTC 2023
|
||
|
NCI_THESAURUS |
C637
Created by
admin on Fri Dec 15 16:16:47 UTC 2023 , Edited by admin on Fri Dec 15 16:16:47 UTC 2023
|
||
|
WHO-VATC |
QD08AL30
Created by
admin on Fri Dec 15 16:16:47 UTC 2023 , Edited by admin on Fri Dec 15 16:16:47 UTC 2023
|
||
|
Food Contact Sustance Notif, (FCN No.) |
FCN NO. 430
Created by
admin on Fri Dec 15 16:16:47 UTC 2023 , Edited by admin on Fri Dec 15 16:16:47 UTC 2023
|
||
|
WHO-VATC |
QS01AX02
Created by
admin on Fri Dec 15 16:16:47 UTC 2023 , Edited by admin on Fri Dec 15 16:16:47 UTC 2023
|
||
|
WHO-ATC |
D08AL30
Created by
admin on Fri Dec 15 16:16:47 UTC 2023 , Edited by admin on Fri Dec 15 16:16:47 UTC 2023
|
||
|
JECFA EVALUATION |
INS-174
Created by
admin on Fri Dec 15 16:16:47 UTC 2023 , Edited by admin on Fri Dec 15 16:16:47 UTC 2023
|
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
9785
Created by
admin on Fri Dec 15 16:16:47 UTC 2023 , Edited by admin on Fri Dec 15 16:16:47 UTC 2023
|
PRIMARY | RxNorm | ||
|
9141
Created by
admin on Fri Dec 15 16:16:47 UTC 2023 , Edited by admin on Fri Dec 15 16:16:47 UTC 2023
|
PRIMARY | |||
|
87370-84-1
Created by
admin on Fri Dec 15 16:16:47 UTC 2023 , Edited by admin on Fri Dec 15 16:16:47 UTC 2023
|
SUPERSEDED | |||
|
23954
Created by
admin on Fri Dec 15 16:16:47 UTC 2023 , Edited by admin on Fri Dec 15 16:16:47 UTC 2023
|
PRIMARY | |||
|
30512
Created by
admin on Fri Dec 15 16:16:47 UTC 2023 , Edited by admin on Fri Dec 15 16:16:47 UTC 2023
|
PRIMARY | |||
|
CHEMBL1230866
Created by
admin on Fri Dec 15 16:16:47 UTC 2023 , Edited by admin on Fri Dec 15 16:16:47 UTC 2023
|
PRIMARY | |||
|
DB12965
Created by
admin on Fri Dec 15 16:16:47 UTC 2023 , Edited by admin on Fri Dec 15 16:16:47 UTC 2023
|
PRIMARY | |||
|
m9913
Created by
admin on Fri Dec 15 16:16:47 UTC 2023 , Edited by admin on Fri Dec 15 16:16:47 UTC 2023
|
PRIMARY | Merck Index | ||
|
3M4G523W1G
Created by
admin on Fri Dec 15 16:16:47 UTC 2023 , Edited by admin on Fri Dec 15 16:16:47 UTC 2023
|
PRIMARY | |||
|
SUB15243MIG
Created by
admin on Fri Dec 15 16:16:47 UTC 2023 , Edited by admin on Fri Dec 15 16:16:47 UTC 2023
|
PRIMARY | |||
|
D012834
Created by
admin on Fri Dec 15 16:16:47 UTC 2023 , Edited by admin on Fri Dec 15 16:16:47 UTC 2023
|
PRIMARY | |||
|
7440-22-4
Created by
admin on Fri Dec 15 16:16:47 UTC 2023 , Edited by admin on Fri Dec 15 16:16:47 UTC 2023
|
PRIMARY | |||
|
DTXSID4024305
Created by
admin on Fri Dec 15 16:16:47 UTC 2023 , Edited by admin on Fri Dec 15 16:16:47 UTC 2023
|
PRIMARY | |||
|
SUB15246MIG
Created by
admin on Fri Dec 15 16:16:47 UTC 2023 , Edited by admin on Fri Dec 15 16:16:47 UTC 2023
|
PRIMARY | |||
|
50826
Created by
admin on Fri Dec 15 16:16:47 UTC 2023 , Edited by admin on Fri Dec 15 16:16:47 UTC 2023
|
PRIMARY | |||
|
3M4G523W1G
Created by
admin on Fri Dec 15 16:16:47 UTC 2023 , Edited by admin on Fri Dec 15 16:16:47 UTC 2023
|
PRIMARY | |||
|
5034
Created by
admin on Fri Dec 15 16:16:47 UTC 2023 , Edited by admin on Fri Dec 15 16:16:47 UTC 2023
|
PRIMARY | |||
|
Silver
Created by
admin on Fri Dec 15 16:16:47 UTC 2023 , Edited by admin on Fri Dec 15 16:16:47 UTC 2023
|
PRIMARY | |||
|
100000078458
Created by
admin on Fri Dec 15 16:16:47 UTC 2023 , Edited by admin on Fri Dec 15 16:16:47 UTC 2023
|
PRIMARY | |||
|
C84590
Created by
admin on Fri Dec 15 16:16:47 UTC 2023 , Edited by admin on Fri Dec 15 16:16:47 UTC 2023
|
PRIMARY | |||
|
231-131-3
Created by
admin on Fri Dec 15 16:16:47 UTC 2023 , Edited by admin on Fri Dec 15 16:16:47 UTC 2023
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
ACTIVE MOIETY |
