Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | Ag |
| Molecular Weight | 107.8682 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Ag]
InChI
InChIKey=BQCADISMDOOEFD-UHFFFAOYSA-N
InChI=1S/Ag
| Molecular Formula | Ag |
| Molecular Weight | 107.8682 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Silver is a soft metal that is used medically in surgical instruments, dental prostheses, and alloys. According to FDA final rule, all over-the-counter drug products containing colloidal silver ingredients or silver salts for internal or external use are not generally recognized as safe and effective and are misbranded.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Integrative analysis of genes and miRNA alterations in human embryonic stem cells-derived neural cells after exposure to silver nanoparticles. | 2016-05-15 |
|
| Silver and titanium dioxide nanoparticles alter oxidative/inflammatory response and renin-angiotensin system in brain. | 2015-11 |
|
| Cyto- and genotoxic effects of metallic nanoparticles in untransformed human fibroblast. | 2015-10 |
|
| Silver nanoparticle exposure induces rat motor dysfunction through decrease in expression of calcium channel protein in cerebellum. | 2015-09-02 |
|
| Nanotoxicity of silver nanoparticles to red blood cells: size dependent adsorption, uptake, and hemolytic activity. | 2015-03-16 |
|
| Difference in the toxicity mechanism between ion and nanoparticle forms of silver in the mouse lung and in macrophages. | 2015-02-03 |
|
| Influence of physicochemical properties of silver nanoparticles on mast cell activation and degranulation. | 2015-02 |
|
| Evaluation of cytotoxic, oxidative stress, proinflammatory and genotoxic effect of silver nanoparticles in human lung epithelial cells. | 2015-02 |
|
| Synaptic degeneration in rat brain after prolonged oral exposure to silver nanoparticles. | 2015-01 |
|
| The cellular and genomic response of rat dopaminergic neurons (N27) to coated nanosilver. | 2014-12 |
|
| Silver and fullerene nanoparticles' effect on interleukin-2-dependent proliferation of CD4 (+) T cells. | 2014-12 |
|
| Heavy metals induce oxidative stress and trigger oxidative stress-mediated heat shock protein (hsp) modulation in the intertidal copepod Tigriopus japonicus. | 2014-11 |
|
| Integrated mRNA and micro RNA profiling reveals epigenetic mechanism of differential sensitivity of Jurkat T cells to AgNPs and Ag ions. | 2014-08-17 |
|
| Silver nanoparticles induce p53-mediated apoptosis in human bronchial epithelial (BEAS-2B) cells. | 2014-06 |
|
| Silver nanoparticles induced changes in the expression of NF-κB related genes are cell type specific and related to the basal activity of NF-κB. | 2014-06 |
|
| Sub-acute intravenous administration of silver nanoparticles in male mice alters Leydig cell function and testosterone levels. | 2014-06 |
|
| Copper is required for oncogenic BRAF signalling and tumorigenesis. | 2014-05-22 |
|
| Silver nanoparticles induce anti-proliferative effects on airway smooth muscle cells. Role of nitric oxide and muscarinic receptor signaling pathway. | 2014-01-13 |
|
| Genotoxicity of silver and titanium dioxide nanoparticles in bone marrow cells of rats in vivo. | 2014-01-06 |
|
| Mechanistic study on the biological effects of silver and gold nanoparticles in Caco-2 cells--induction of the Nrf2/HO-1 pathway by high concentrations of silver nanoparticles. | 2014-01-03 |
|
| Silver nanoparticles induce endoplasmatic reticulum stress response in zebrafish. | 2013-10-15 |
|
| Investigating oxidative stress and inflammatory responses elicited by silver nanoparticles using high-throughput reporter genes in HepG2 cells: effect of size, surface coating, and intracellular uptake. | 2013-09 |
|
| Hypoxia inducible factor-1 (HIF-1)-flavin containing monooxygenase-2 (FMO-2) signaling acts in silver nanoparticles and silver ion toxicity in the nematode, Caenorhabditis elegans. | 2013-07-15 |
|
| Non-hepatic tumors change the activity of genes encoding copper trafficking proteins in the liver. | 2013-07 |
|
| Effects of silver nanoparticles on the liver and hepatocytes in vitro. | 2013-02 |
|
| Silver nanoparticle-induced cytotoxicity in rat brain endothelial cell culture. | 2013-02 |
|
| Contributions of rat Ctr1 to the uptake and toxicity of copper and platinum anticancer drugs in dorsal root ganglion neurons. | 2013-01-15 |
|
| Toxicity of silver nanoparticles to rainbow trout: a toxicogenomic approach. | 2012-10 |
|
| Cellular uptake, intracellular trafficking and cytotoxicity of silver nanoparticles. | 2012-09-03 |
|
| Silver nanoparticle-induced mutations and oxidative stress in mouse lymphoma cells. | 2012-07 |
|
| Silver nanoparticles-mediated G2/M cycle arrest of renal epithelial cells is associated with NRF2-GSH signaling. | 2012-06-20 |
|
| [Structure-functional organization of eukaryotic high-affinity copper importer CTR1 determines its ability to transport copper, silver and cisplatin]. | 2012-06-08 |
|
| Toxicogenomic responses of nanotoxicity in Daphnia magna exposed to silver nitrate and coated silver nanoparticles. | 2012-06-05 |
|
| Distinct immunomodulatory effects of a panel of nanomaterials in human dermal fibroblasts. | 2012-05-05 |
|
| Silica nanoparticles and silver-doped silica nanoparticles induce endoplasmatic reticulum stress response and alter cytochrome P4501A activity. | 2012-04 |
|
| Effects of silver nanoparticles on primary mixed neural cell cultures: uptake, oxidative stress and acute calcium responses. | 2012-04 |
|
| Cytotoxic and genotoxic effects of silver nanoparticles in testicular cells. | 2012-01-27 |
|
| Role of the Nrf2-heme oxygenase-1 pathway in silver nanoparticle-mediated cytotoxicity. | 2012-01-01 |
|
| Exposure to silver nanoparticles inhibits selenoprotein synthesis and the activity of thioredoxin reductase. | 2012-01 |
|
| Silver nanoparticles induce apoptosis and G2/M arrest via PKCζ-dependent signaling in A549 lung cells. | 2011-12 |
|
| Silver nanoparticles down-regulate Nrf2-mediated 8-oxoguanine DNA glycosylase 1 through inactivation of extracellular regulated kinase and protein kinase B in human Chang liver cells. | 2011-11-30 |
|
| Characterization of MtnE, the fifth metallothionein member in Drosophila. | 2011-10 |
|
| Vascular tube formation and angiogenesis induced by polyvinylpyrrolidone-coated silver nanoparticles. | 2011-09-10 |
|
| Physicochemical characterization and in vitro hemolysis evaluation of silver nanoparticles. | 2011-09 |
|
| Cu/Zn- and Mn-superoxide dismutase (SOD) from the copepod Tigriopus japonicus: molecular cloning and expression in response to environmental pollutants. | 2011-09 |
|
| The lumenal loop Met672-Pro707 of copper-transporting ATPase ATP7A binds metals and facilitates copper release from the intramembrane sites. | 2011-07-29 |
|
| Silver nanoparticles induce oxidative cell damage in human liver cells through inhibition of reduced glutathione and induction of mitochondria-involved apoptosis. | 2011-02-25 |
|
| Identification, characterization and expression profiles of Chironomus riparius glutathione S-transferase (GST) genes in response to cadmium and silver nanoparticles exposure. | 2011-02 |
|
| Experimental switching of copper status in laboratory rodents. | 2011-01 |
|
| NRF2 Oxidative Stress Induced by Heavy Metals is Cell Type Dependent. | 2011 |
| Substance Class |
Chemical
Created
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| Record UNII |
3M4G523W1G
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| Record Status |
Validated (UNII)
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DSLD |
599 (Number of products:3)
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CFR |
21 CFR 310.548
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DSLD |
2291 (Number of products:128)
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DSLD |
675 (Number of products:6)
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EPA PESTICIDE CODE |
72599
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EPA PESTICIDE CODE |
72501
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NCI_THESAURUS |
C637
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WHO-VATC |
QD08AL30
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Food Contact Sustance Notif, (FCN No.) |
FCN NO. 430
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WHO-VATC |
QS01AX02
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WHO-ATC |
D08AL30
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JECFA EVALUATION |
INS-174
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9785
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9141
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87370-84-1
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23954
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30512
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CHEMBL1230866
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DB12965
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m9913
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3M4G523W1G
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SUB15243MIG
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D012834
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7440-22-4
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DTXSID4024305
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SUB15246MIG
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50826
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3M4G523W1G
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5034
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Silver
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100000078458
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C84590
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231-131-3
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ACTIVE MOIETY |
