U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 10601 - 10610 of 10822 results


Class (Stereo):
CHEMICAL (ACHIRAL)

Distearyl dimethyl ammonium bromide (or dimethyldioctadecylammonium bromide (or DDA), a quaternary ammonium salt, that stimulates immune responses and binds to antigens. DDA enhances the immunogenicity of the soluble antigen. It was shown, that complexes of DDA and antigen were effective in eliciting a delayed hypersensitivity reaction, which was desirable for an antitumor effect. Besides, as a part of liposomal adjuvants, DDA can modulate T-helper 1-immune responses.
Status:
Possibly Marketed Outside US
Source:
Canada:MALACHITE GREEN
Source URL:
First approved in 1985

Class (Stereo):
CHEMICAL (ACHIRAL)


Malachite green, an N-methylated diaminotriphenylmethane dye, is used primarily as a therapeutic agent in aquaculture. It controls fungal attacks, protozoan infections and some other diseases caused by helminths on a wide variety of fish and other aquatic organisms. In solution, the dye exists as a mixture of the cation (chromatic malachite green) and its carbinol base, with the ratio depending on the pH of the solution; the dye also can undergo chemical and metabolic reduction to a leuco derivative. Malachite green intercalates with DNA, with a preference for A:T-rich regions, and the leuco derivative bears a structural resemblance to carcinogenic aromatic amines that can form covalent DNA adducts. In mammalian cells, it shows marked cytotoxicity and the ability to induce cell transformation and lipid peroxidation. The toxicity of this dye increases with exposure time, temperature and concentration. It has been reported to cause carcinogenesis, mutagenesis, chromosomal fractures, teratogenecity and respiratory toxicity.
Status:
Possibly Marketed Outside US
Source:
Canada:DIDECYL DIMETHYL AMMONIUM CHLORIDE
Source URL:
First approved in 1978
Source:
Dairyland Brand Teat Dip by Stearns Packaging Corporation
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

DIDECYLDIMONIUM (as a salt, didecyldimethylammonium chloride (DDAC)) is used in many types of biocidal products including tableware, carpets, humidifiers, and swimming pools. It shows a broad spectrum of activity against both gram-positive and gram-negative bacteria and is also effective on fungi and viruses, including those that are enveloped.
Status:
Possibly Marketed Outside US
Source:
Canada:DIDECYL DIMETHYL AMMONIUM CHLORIDE
Source URL:
First approved in 1978
Source:
Dairyland Brand Teat Dip by Stearns Packaging Corporation
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

DIDECYLDIMONIUM (as a salt, didecyldimethylammonium chloride (DDAC)) is used in many types of biocidal products including tableware, carpets, humidifiers, and swimming pools. It shows a broad spectrum of activity against both gram-positive and gram-negative bacteria and is also effective on fungi and viruses, including those that are enveloped.
Status:
Possibly Marketed Outside US
Source:
Canada:DIDECYL DIMETHYL AMMONIUM CHLORIDE
Source URL:
First approved in 1978
Source:
Dairyland Brand Teat Dip by Stearns Packaging Corporation
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

DIDECYLDIMONIUM (as a salt, didecyldimethylammonium chloride (DDAC)) is used in many types of biocidal products including tableware, carpets, humidifiers, and swimming pools. It shows a broad spectrum of activity against both gram-positive and gram-negative bacteria and is also effective on fungi and viruses, including those that are enveloped.
Status:
Possibly Marketed Outside US
Source:
Canada:DIDECYL DIMETHYL AMMONIUM CHLORIDE
Source URL:
First approved in 1978
Source:
Dairyland Brand Teat Dip by Stearns Packaging Corporation
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

DIDECYLDIMONIUM (as a salt, didecyldimethylammonium chloride (DDAC)) is used in many types of biocidal products including tableware, carpets, humidifiers, and swimming pools. It shows a broad spectrum of activity against both gram-positive and gram-negative bacteria and is also effective on fungi and viruses, including those that are enveloped.
Status:
Possibly Marketed Outside US
Source:
Canada:DIDECYL DIMETHYL AMMONIUM CHLORIDE
Source URL:
First approved in 1978
Source:
Dairyland Brand Teat Dip by Stearns Packaging Corporation
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

DIDECYLDIMONIUM (as a salt, didecyldimethylammonium chloride (DDAC)) is used in many types of biocidal products including tableware, carpets, humidifiers, and swimming pools. It shows a broad spectrum of activity against both gram-positive and gram-negative bacteria and is also effective on fungi and viruses, including those that are enveloped.
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)


Benzododecinium, a quaternary ammonium compound, is an antiseptic agent and disinfectant. Benzododecinium is used as preservative in different pharmaceutical formulations. Thus, the dispenser of Timoptol-LA, used for the treatment of patients with ocular hypertension, contains benzododecinium bromide as a preservative. It is used as preservative and the corneal permeability enhancer in formulation. Benzododecinium is effective against gram-positive microbes.
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)


Benzododecinium, a quaternary ammonium compound, is an antiseptic agent and disinfectant. Benzododecinium is used as preservative in different pharmaceutical formulations. Thus, the dispenser of Timoptol-LA, used for the treatment of patients with ocular hypertension, contains benzododecinium bromide as a preservative. It is used as preservative and the corneal permeability enhancer in formulation. Benzododecinium is effective against gram-positive microbes.

Showing 10601 - 10610 of 10822 results