Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C38H80N.Br |
| Molecular Weight | 630.953 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Br-].CCCCCCCCCCCCCCCCCC[N+](C)(C)CCCCCCCCCCCCCCCCCC
InChI
InChIKey=PSLWZOIUBRXAQW-UHFFFAOYSA-M
InChI=1S/C38H80N.BrH/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-37-39(3,4)38-36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-2;/h5-38H2,1-4H3;1H/q+1;/p-1
Distearyl dimethyl ammonium bromide (or dimethyldioctadecylammonium bromide (or DDA), a quaternary ammonium salt, that stimulates immune responses and binds to antigens. DDA enhances the immunogenicity of the soluble antigen. It was shown, that complexes of DDA and antigen were effective in eliciting a delayed hypersensitivity reaction, which was desirable for an antitumor effect. Besides, as a part of liposomal adjuvants, DDA can modulate T-helper 1-immune responses.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Liposomes based on dimethyldioctadecylammonium promote a depot effect and enhance immunogenicity of soluble antigen. | 2010-03-03 |
|
| Interaction of antigens with dimethyldioctadecylammonium bromide, a chemically defined biological response modifier. | 1982-12 |
|
| The enhancement of humoral and cellular immune responses by dimethyldioctadecylammonium bromide. | 1980-02 |
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Dimethyldioctadecylammonium bromide
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100000161014
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3700-67-2
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77293
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223-037-6
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Z5T47R065A
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DTXSID60884005
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SUBSTANCE RECORD
