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Details

Stereochemistry ACHIRAL
Molecular Formula C38H80N.Br
Molecular Weight 630.953
Optical Activity NONE
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DISTEARYL DIMETHYL AMMONIUM BROMIDE

SMILES

[Br-].CCCCCCCCCCCCCCCCCC[N+](C)(C)CCCCCCCCCCCCCCCCCC

InChI

InChIKey=PSLWZOIUBRXAQW-UHFFFAOYSA-M
InChI=1S/C38H80N.BrH/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-37-39(3,4)38-36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-2;/h5-38H2,1-4H3;1H/q+1;/p-1

HIDE SMILES / InChI
Molecular Formula BrH
Molecular Weight 80.912
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C38H80N
Molecular Weight 551.0485
Charge 1
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity NONE

Description

Distearyl dimethyl ammonium bromide (or dimethyldioctadecylammonium bromide (or DDA), a quaternary ammonium salt, that stimulates immune responses and binds to antigens. DDA enhances the immunogenicity of the soluble antigen. It was shown, that complexes of DDA and antigen were effective in eliciting a delayed hypersensitivity reaction, which was desirable for an antitumor effect. Besides, as a part of liposomal adjuvants, DDA can modulate T-helper 1-immune responses.

Approval Year

1987
121
PubMed

PubMed

TitleDatePubMed
Liposomes based on dimethyldioctadecylammonium promote a depot effect and enhance immunogenicity of soluble antigen.
2010-03-03
Interaction of antigens with dimethyldioctadecylammonium bromide, a chemically defined biological response modifier.
1982-12
The enhancement of humoral and cellular immune responses by dimethyldioctadecylammonium bromide.
1980-02
Substance Class Chemical
Created
by admin
on Mon Mar 31 23:35:14 GMT 2025
Edited
by admin
on Mon Mar 31 23:35:14 GMT 2025
Record UNII
Z5T47R065A
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DISTEARYLDIMONIUM BROMIDE
Preferred Name English
DISTEARYL DIMETHYL AMMONIUM BROMIDE
Systematic Name English
DSDMAB
Common Name English
DISTEARYLDIMETHYLAMMONIUM BROMIDE
Systematic Name English
DI-N-OCTADECYLDIMETHYLAMMONIUM BROMIDE
Systematic Name English
BIS(OCTADECYL)DIMETHYLAMMONIUM BROMIDE
Systematic Name English
DIOCTADECYLDIMETHYLAMMONIUM BROMIDE
Systematic Name English
1-OCTADECANAMINIUM, N,N-DIMETHYL-N-OCTADECYL-, BROMIDE (1:1)
Systematic Name English
N,N-DISTEARYL-N,N-DIMETHYLAMMONIUM BROMIDE
Systematic Name English
Code System Code Type Description
WIKIPEDIA
Dimethyldioctadecylammonium bromide
Created by admin on Mon Mar 31 23:35:14 GMT 2025 , Edited by admin on Mon Mar 31 23:35:14 GMT 2025
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SMS_ID
100000161014
Created by admin on Mon Mar 31 23:35:14 GMT 2025 , Edited by admin on Mon Mar 31 23:35:14 GMT 2025
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CAS
3700-67-2
Created by admin on Mon Mar 31 23:35:14 GMT 2025 , Edited by admin on Mon Mar 31 23:35:14 GMT 2025
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PUBCHEM
77293
Created by admin on Mon Mar 31 23:35:14 GMT 2025 , Edited by admin on Mon Mar 31 23:35:14 GMT 2025
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ECHA (EC/EINECS)
223-037-6
Created by admin on Mon Mar 31 23:35:14 GMT 2025 , Edited by admin on Mon Mar 31 23:35:14 GMT 2025
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FDA UNII
Z5T47R065A
Created by admin on Mon Mar 31 23:35:14 GMT 2025 , Edited by admin on Mon Mar 31 23:35:14 GMT 2025
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EPA CompTox
DTXSID60884005
Created by admin on Mon Mar 31 23:35:14 GMT 2025 , Edited by admin on Mon Mar 31 23:35:14 GMT 2025
PRIMARY
NIH
NCATS
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