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Search results for angiotensin root_codes_url in Code URL (approximate match)
Manganomanganic oxide is an oxide of Mn (II,III) with is formula of Mn3O4. It was proposed as a food supplement for prevention of manganese deficiency in animals and fish. The manganomanganic oxide Elkem Agrimax contained a lead mixture, and because of it was not approved for animal use by Scientific Committee for Animal Nutrition
There is no information about biological or medical application of ferrous oxalate. But is known, this substance is an insoluble in water.
There is no information related to the pharmacological activity of COBALTOUS OXALATE (cobalt oxalate), but is existed a mention about biological activity, where were investigated the role of anions, such as sulfate, nitrate, oxalate and acetate on pharmacological properties of metal (including Co), these complexes have been screened against bacterial species, Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa and results have been reported. In addition is known that cobalt oxalate primarily used as catalysts.
Ni acetate is a water soluble salt of Ni, which leads to skin irritation, in particular to allergic contact dermatitis. May cause cancer according to animal studies. Symptoms of overexposure to nickel can cause sensitization, dermatitis, allergic asthma and pneumonitis.
Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Isosafrole, a stiripentol analog, is a potent LDH inhibitor. Stiripentol is a new-generation antiepileptic drug, and its chemical structure is unrelated to other antiepileptic drugs. Seizures and epileptiform activity are reduced by inhibition of the metabolic pathway via lactate dehydrogenase (LDH), which is a component of the astrocyte-neuron lactate shuttle.
Isosafrole is a substructure of stiripentol that lacks the hydroxyl group and tertiary-butyl group of stiripentol. Isosafrole strongly inhibited the pyruvate-to-lactate conversion by both LDH1 and LDH5, suggesting that it inhibits lactate production itself. Isosafrole suppresses seizures in vivo. Going by the lactate reduction by ketogenic diets, LDH inhibitors for the pyruvate-to-lactate conversion, such as isosafrole, would be more effective for antiepileptic actions. Isosafrole is a known inducer of some of the liver enzymes of the cytochrome P-450 group in rodents, especially CYP1A2.