Cyclothiazide was presumably developed by Eli Lilly for the treatment of hypertension. It is believed that the drug, which belongs to the class of thiazide diuretics, exerts its action by inhibitin sodium reabsorption in the renal tubules. In 1993 it was discovered that cyclothiazide stimulates AMPA receptors thus inducing seizure behavior.

Merethoxylline is a mercurial diuretic. As an equimolar mixture of merethoxylline procaine and theophylline in the molecular proportion 1:1.4 (DICURIN PROCAINE, Lilly) has been used in the treatment of oedema and ascites. The procaine component helps in reducing the discomfort of local irritation caused by mercurial compound when injected into tissues.

Merethoxylline is a mercurial diuretic. As an equimolar mixture of merethoxylline procaine and theophylline in the molecular proportion 1:1.4 (DICURIN PROCAINE, Lilly) has been used in the treatment of oedema and ascites. The procaine component helps in reducing the discomfort of local irritation caused by mercurial compound when injected into tissues.