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Details

Stereochemistry RACEMIC
Molecular Formula C15H20HgNO6.HO
Molecular Weight 527.92
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of MERETHOXYLLINE

SMILES

[OH-].COCCOC(C[Hg+])CNC(=O)C1=C(OCC(O)=O)C=CC=C1

InChI

InChIKey=NQNRRALXOYEOGG-UHFFFAOYSA-M
InChI=1S/C15H20NO6.Hg.H2O/c1-11(21-8-7-20-2)9-16-15(19)12-5-3-4-6-13(12)22-10-14(17)18;;/h3-6,11H,1,7-10H2,2H3,(H,16,19)(H,17,18);;1H2/q;+1;/p-1

HIDE SMILES / InChI
Merethoxylline is a mercurial diuretic. As an equimolar mixture of merethoxylline procaine and theophylline in the molecular proportion 1:1.4 (DICURIN PROCAINE, Lilly) has been used in the treatment of oedema and ascites. The procaine component helps in reducing the discomfort of local irritation caused by mercurial compound when injected into tissues.

Approval Year

TargetsConditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
DICURIN PROCAINE

Approved Use

DICURIN PROCAINE has been used in the treatment of oedema and ascites.

Launch Date

3.78604814E11
Primary
DICURIN PROCAINE

Approved Use

DICURIN PROCAINE has been used in the treatment of oedema and ascites.

Launch Date

3.78604814E11
PubMed

PubMed

TitleDatePubMed
Study of the mercurial diuretic, dicurin procaine (merethoxylline procaine) by subcutaneous injection.
1953 Feb
NEW AND nonofficial remedies: merethoxylline.
1954 Aug 21
NEW AND nonofficial remedies: merethoxylline procaine.
1954 Aug 21
Patents

Patents

Sample Use Guides

Ususal i.m., s.c. daily 0.5 to 5 ml (containing 100 mg procaine merethoxylline and 50 mg of theophylline per ml)
Route of Administration: Other
In Vitro Use Guide
Unknown
Name Type Language
MERETHOXYLLINE
Common Name English
DEHYDRO-2-(N-(3'-HYDROXYMERCURI-2'-METHOXYETHOXY)PROPYLCARBAMOYL)PHENOXYACETIC ACID
Common Name English
MERCURATE(1-), (3-((((2-(CARBOXYLATOMETHOXY)PHENYL)AMINO)CARBONYL-.KAPPA.O)AMINO)-2-(2-HYDROXYETHOXY)PROPYL-.KAPPA.C)HYDROXY-
Systematic Name English
Code System Code Type Description
CAS
61218-47-1
Created by admin on Sat Dec 16 09:13:40 UTC 2023 , Edited by admin on Sat Dec 16 09:13:40 UTC 2023
PRIMARY
PUBCHEM
91667974
Created by admin on Sat Dec 16 09:13:40 UTC 2023 , Edited by admin on Sat Dec 16 09:13:40 UTC 2023
PRIMARY
FDA UNII
1AQ60H5GT2
Created by admin on Sat Dec 16 09:13:40 UTC 2023 , Edited by admin on Sat Dec 16 09:13:40 UTC 2023
PRIMARY
EPA CompTox
DTXSID801027259
Created by admin on Sat Dec 16 09:13:40 UTC 2023 , Edited by admin on Sat Dec 16 09:13:40 UTC 2023
PRIMARY