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Primary Target

Streptococcus mutans

41

Histamine H1 receptor

316

Dopamine D2 receptor

311

DNA

282

Serotonin 2a (5-HT2a) receptor

237

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Development Status

US Approved OTC

38

Other

2

Possibly Marketed Outside US

1

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Highest Phase

Approved

39

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Approval Year

1921

38

Unknown

3

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Condition

Acute myeloid leukemia

38

Breast cancer

38

Caries

38

Diaper dermatitis

38

Dysgeusia

38

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Treatment Modality

Primary

40

Preventing

38

Secondary

38

Curative

2

Inactive ingredient

1

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CNS Activity

CNS Active

39

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Originator

Smithson, R.

38

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Substance Class

Chemical

39

Mixture

1

Protein

1

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Code System

FDA UNII

41

CAS

40

PUBCHEM

40

EPA CompTox

38

RXCUI

25

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ATC Level 1

ALIMENTARY TRACT AND METABOLISM

3

BLOOD AND BLOOD FORMING ORGANS

1

DERMATOLOGICALS

1

VARIOUS

1

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ATC Level 2

MINERAL SUPPLEMENTS

2

ALL OTHER THERAPEUTIC PRODUCTS

1

BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS

1

MEDICATED DRESSINGS

1

OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS

1

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ATC Level 3

OTHER MINERAL SUPPLEMENTS

2

ALL OTHER THERAPEUTIC PRODUCTS

1

I.V. SOLUTION ADDITIVES

1

MEDICATED DRESSINGS

1

OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS

1

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ATC Level 4

Zinc

2

Detoxifying agents for antineoplastic treatment

1

Electrolyte solutions

1

Various alimentary tract and metabolism products

1

Zinc bandages

1

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Substance Form

Salts, Hydrates, Esters, etc.

37

Principal Form

4

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Showing 1 - 10 of 41 results

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ZINC CATION

13S1S8SF37

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Status:

US Approved OTC

First marketed in 1921

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

respiratory burst

Streptococcus mutans

transformed cell apoptotic process

ultraviolet B-induced damage

T cell mediated immunity

Zinc transporter ZIP1

Zinc transporter ZIP2

Conditions:

Renal insufficiency

Ulcerative colitis

Acute myeloid leukemia

Zinc deficiency

Poison Ivy dermatitis

Diaper dermatitis

Gastrointestinal disorders

There is no available information related any biological and pharmaceutical application of ammonium tetrachlorozincate.

POTASSIUM LINOLEATE

3S022W5099

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Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Streptococcus mutans

Conditions:

Streptococcal Infections

Potassium linoleate is a cosmetic agent, also used as a surfactant, emulsifying ingredient and thickener. Potassium linoleate has being shown to possess high antibacterial activity against S. mutans, and possess great potential as antibacterial agent...

.

QUERCITRIN

2Y8906LC5P

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Status:

Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

Aldose reductase

Streptococcus mutans

Maltase-glucoamylase

Angiotensin-converting enzyme

Ribosomal protein S6 kinase alpha-3

Conditions:

Non-small cell lung cancer

Lupus erythematosus

Lung inflammatory diseases

Diabetic nephropathy

Quercitrin is known as a bio flavonoid antioxidant and was investigated extensively in its antioxidant potential in streptrozotocin (STZ)-induced diabetic rats. Quercitrin is also a constituent of the dye quercitron. Quercitrin can be found in Tartar...

y buckwheat and in oaks species such as white oak or European red oak. Quercitrin has potential anti-inflammation effect that is used to treat heart and vascular conditions. Quercitrin offers protection against brain injury in mice by inhibiting oxidative stress and inflammation. Quercitrin also prevented CCl4 induced cerebral function disorders associated with its ability to inhibit the activities of monoamine oxidase (MAO), acetylcholine esterase (AChE) and the N-methyl-d-aspartate receptor 2B subunit (NR2B). Quercitrin suppressed the release of pro-inflammatory cytokines such as tumor necrosis factor alpha (TNF-α) and interleukin-6 (IL-6). Quercitrin may be a potential candidate to be developed as a neuroprotective agent. Quercitrin has been used previously as an antibacterial agent and has been shown to inhibit the oxidation of low-density lipoproteins and prevent an allergic reaction. It was demonstrated that quercitrin exerts protective effects against H2O2-induced dysfunction in lung fibroblast cells. Quercitrin has antiproliferative and apoptotic effects on lung cancer cells by modulating the immune response. There were significant increases in caspase-3 activity, loss of MMP, and increases in the apoptotic cell population in response to quercitrin in DLD-1 colon cancer cells in a time- and dose-dependent manner. These results revealed that quercitrin has antiproliferative and apoptotic effects on colon cancer cells. Quercitrin activity supported with in vivo analyses could be a biomarker candicate for early colorectal carcinoma.

ZINC L-LACTATE

323TLL3AFZ

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Status:

Possibly Marketed Outside US

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

Streptococcus mutans

Gardnerella vaginalis

Herpes simplex virus (type 1 / strain F)

Conditions:

Chronic periodontitis

Bacterial vaginosis

Zinc lactate is used to eliminate halitosis. Halitosis (commonly known as bad breath) is a condition affecting many people and one of the most usual reasons why people go look for a dentist’s advice. The main origin of halitosis is related to the vol...

atile sulphur compounds (VSC) produced by the different bacterial colonies found on the tongue and in the gingival crevices. Zinc lactate is a very effective solution to neutralize the VSC and an excellent ingredient for mouthwashes and toothpastes.

ZINC DIBUTYRATE

VA6XH8E3JX

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Status:

US Approved OTC

First marketed in 1921

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

respiratory burst

Streptococcus mutans

transformed cell apoptotic process

ultraviolet B-induced damage

T cell mediated immunity

Zinc transporter ZIP1

Zinc transporter ZIP2

Conditions:

Renal insufficiency

Ulcerative colitis

Acute myeloid leukemia

Zinc deficiency

Poison Ivy dermatitis

Diaper dermatitis

Gastrointestinal disorders

There is no available information related any biological and pharmaceutical application of ammonium tetrachlorozincate.

ZINC CITRATE DIHYDRATE

021IBV57IL

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Status:

US Approved OTC

First marketed in 1921

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

respiratory burst

Streptococcus mutans

transformed cell apoptotic process

ultraviolet B-induced damage

T cell mediated immunity

Zinc transporter ZIP1

Zinc transporter ZIP2

Conditions:

Renal insufficiency

Ulcerative colitis

Acute myeloid leukemia

Zinc deficiency

Poison Ivy dermatitis

Diaper dermatitis

Gastrointestinal disorders

There is no available information related any biological and pharmaceutical application of ammonium tetrachlorozincate.

ZINC SUCCINATE

IY01B595GR

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Status:

US Approved OTC

First marketed in 1921

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

respiratory burst

Streptococcus mutans

transformed cell apoptotic process

ultraviolet B-induced damage

T cell mediated immunity

Zinc transporter ZIP1

Zinc transporter ZIP2

Conditions:

Renal insufficiency

Ulcerative colitis

Acute myeloid leukemia

Zinc deficiency

Poison Ivy dermatitis

Diaper dermatitis

Gastrointestinal disorders

There is no available information related any biological and pharmaceutical application of ammonium tetrachlorozincate.

ZINC OROTATE DIHYDRATE

2R18GO895S

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Status:

US Approved OTC

First marketed in 1921

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

respiratory burst

Streptococcus mutans

transformed cell apoptotic process

ultraviolet B-induced damage

T cell mediated immunity

Zinc transporter ZIP1

Zinc transporter ZIP2

Conditions:

Renal insufficiency

Ulcerative colitis

Acute myeloid leukemia

Zinc deficiency

Poison Ivy dermatitis

Diaper dermatitis

Gastrointestinal disorders

There is no available information related any biological and pharmaceutical application of ammonium tetrachlorozincate.

ZINC MONOCARBONATE

K8290PTQ4F

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Status:

US Approved OTC

First marketed in 1921

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

respiratory burst

Streptococcus mutans

transformed cell apoptotic process

ultraviolet B-induced damage

T cell mediated immunity

Zinc transporter ZIP1

Zinc transporter ZIP2

Conditions:

Renal insufficiency

Ulcerative colitis

Acute myeloid leukemia

Zinc deficiency

Poison Ivy dermatitis

Diaper dermatitis

Gastrointestinal disorders

There is no available information related any biological and pharmaceutical application of ammonium tetrachlorozincate.

ZINC NITRIDE

7OOJ6UE14L

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Status:

US Approved OTC

First marketed in 1921

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

respiratory burst

Streptococcus mutans

transformed cell apoptotic process

ultraviolet B-induced damage

T cell mediated immunity

Zinc transporter ZIP1

Zinc transporter ZIP2

Conditions:

Renal insufficiency

Ulcerative colitis

Acute myeloid leukemia

Zinc deficiency

Poison Ivy dermatitis

Diaper dermatitis

Gastrointestinal disorders

There is no available information related any biological and pharmaceutical application of ammonium tetrachlorozincate.

Showing 1 - 10 of 41 results

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