POTASSIUM LINOLEATE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C18H31O2.K
Molecular Weight	318.5358
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	2
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[K+].CCCCC\C=C/C\C=C/CCCCCCCC([O-])=O

InChI

InChIKey=BAYJYBALPIYBQQ-NBTZWHCOSA-M

InChI=1S/C18H32O2.K/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h6-7,9-10H,2-5,8,11-17H2,1H3,(H,19,20);/q;+1/p-1/b7-6-,10-9-;

HIDE SMILES / InChI

Molecular Formula	K
Molecular Weight	39.0983
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C18H31O2
Molecular Weight	279.4375
Charge	-1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	2
Optical Activity	NONE

Description
Sources: http://www.thegoodscentscompany.com/data/rw1684081.html | https://www.ncbi.nlm.nih.gov/pubmed/26412702 | https://books.google.ru/books?id=3hLmyma2-MsC&pg=PA427&lpg=PA427&dq=POTASSIUM+LINOLEATE

Potassium linoleate is a cosmetic agent, also used as a surfactant, emulsifying ingredient and thickener. Potassium linoleate has being shown to possess high antibacterial activity against S. mutans, and possess great potential as antibacterial agent.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Streptococcus mutans 41 Target ID: CHEMBL612426 Sources: https://www.ncbi.nlm.nih.gov/pubmed/26412702	Inhibitor 8297

Conditions

Condition	Modality	Targets	Highest Phase	Product
Streptococcal Infections 1 Sources: https://www.ncbi.nlm.nih.gov/pubmed/26412702	Curative		Basic research	Unknown Approved Use Unknown

PubMed

Title	Date	PubMed
Ascorbic acid and copper in linoleate oxidation. 3. Catalysts in combination.	1969 Sep	5808830
Effect of hemoglobin concentration on the oxidation of linoleic acid.	1971 Mar	5554105
Enzymatic properties of the lipoxygenase from pea seeds.	1985	3936491
Antibacterial Effect of Fatty Acid Salts on Oral Bacteria.	2015	26412702

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Potassium linoleate (C18:2K), used at a concentration of 175 mM, resulted in a 7 log-unit reduction of S. mutans after a 10-min incubation. The minimum inhibitory concentration (MIC) of C18:2K was 5.5 mM.

Substance Class	Chemical Created by `admin` on `Sat Dec 16 20:01:24 GMT 2023` Edited by `admin` on `Sat Dec 16 20:01:24 GMT 2023`
Record UNII	3S022W5099
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

POTASSIUM LINOLEATE

Official Name

English

LINOLEIC ACID, POTASSIUM SALT

Common Name

English

POTASSIUM LINOLEATE [INCI]

Common Name

English

PRISAVON KL

Common Name

English

Code System Code Type Description

EPA CompTox

DTXSID0041561