Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | 2C3H5O3.Zn |
| Molecular Weight | 243.549 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Zn++].C[C@H]([O-])C(O)=O.C[C@H]([O-])C(O)=O
InChI
InChIKey=UHKOOGWQCULNGT-CEOVSRFSSA-N
InChI=1S/2C3H5O3.Zn/c2*1-2(4)3(5)6;/h2*2H,1H3,(H,5,6);/q2*-1;+2/t2*2-;/m00./s1
Zinc lactate is used to eliminate halitosis. Halitosis (commonly
known as bad breath) is a condition affecting many people and one of the most usual reasons why people go look for a dentist’s advice. The main
origin of halitosis is related to the volatile sulphur compounds (VSC) produced by the different bacterial colonies found on the tongue and in the
gingival crevices. Zinc lactate is a very effective solution to neutralize the VSC and an excellent ingredient for mouthwashes and toothpastes.
Approval Year
Targets
| Primary Target | Pharmacology | Condition | Potency |
|---|---|---|---|
Target ID: CHEMBL613200 |
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Target ID: CHEMBL614731 |
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Target ID: CHEMBL614994 |
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Target ID: CHEMBL612426 |
Conditions
| Condition | Modality | Targets | Highest Phase | Product |
|---|---|---|---|---|
| Primary | Galanium zinc lactate Approved UseGalanium™ zinc lactate is a perfect solution to eliminate halitosis. |
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| Inactive ingredient | Clean and Clear Advantage Acne Control Cleanser Approved UseAcne treatment |
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| Curative | Unknown Approved UseUnknown |
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| Primary | Unknown Approved UseUnknown |
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| Primary | Crest Pro-Health Clinical Gum Protection Clean Mint Toothpaste Approved UseAnticavity, antigingivitis, antisensitivity toothpaste |
PubMed
| Title | Date | PubMed |
|---|---|---|
| Zinc salts inactivate clinical isolates of herpes simplex virus in vitro. | 2000 May |
|
| Effect of different mouthrinses on morning breath. | 2001 Sep |
|
| Assessment of hypersensitivity reduction of a dentifrice containing 0.3% triclosan, 2.0% PVM/MA copolymer, 0.243% NaF and specially-designed silica as compared to a dentifrice containing 0.454% stannous fluoride, sodium hexametaphosphate and zinc lactate and to a dentifrice containing 0.243% NaF on dentin hypersensitivity reduction: an 8-week study. | 2011 Jul |
|
| Aggregates and hydrogels prepared by self-assembly of amphiphilic copolymers with surfactants. | 2012 May 15 |
|
| Dietary zinc deficiency reduced growth performance, intestinal immune and physical barrier functions related to NF-κB, TOR, Nrf2, JNK and MLCK signaling pathway of young grass carp (Ctenopharyngodon idella). | 2017 Jul |
Sample Use Guides
The volunteer rinsed with pre-procedural mouthwash containing 0.075% cetylpyridinium chloride, 0.28% zinc lactate and 0.05% sodium fluoride in an Alcohol-free base for one minute, 20 ml of solution and then expectorated all remaining liquid.
Route of Administration:
Dental
Of 10 randomly chosen clinical isolates of herpes simplex virus (five HSV type 1 [HSV-1] isolates and five HSV-2 isolates), nine were inactivated >97% by treatment with zinc lactate. The effect was concentration dependent. With an HSV-1 isolate, 50 mM zinc lactate caused 100% inactivation, 15 mM caused 98 to 99% inactivation, and 5 mM caused 63 to 86% inactivation. With an HSV-2 isolate, 50 and 15 mM zinc lactate caused greater than 92% inactivation and 5 and 1 mM caused 37 and 26% inactivation, respectively.
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SUBSTANCE RECORD
