U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula 2C3H5O3.Zn
Molecular Weight 243.549
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ZINC L-LACTATE

SMILES

[Zn++].C[C@H]([O-])C(O)=O.C[C@H]([O-])C(O)=O

InChI

InChIKey=UHKOOGWQCULNGT-CEOVSRFSSA-N
InChI=1S/2C3H5O3.Zn/c2*1-2(4)3(5)6;/h2*2H,1H3,(H,5,6);/q2*-1;+2/t2*2-;/m00./s1

HIDE SMILES / InChI
Zinc lactate is used to eliminate halitosis. Halitosis (commonly known as bad breath) is a condition affecting many people and one of the most usual reasons why people go look for a dentist’s advice. The main origin of halitosis is related to the volatile sulphur compounds (VSC) produced by the different bacterial colonies found on the tongue and in the gingival crevices. Zinc lactate is a very effective solution to neutralize the VSC and an excellent ingredient for mouthwashes and toothpastes.

Approval Year

TargetsConditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Galanium zinc lactate

Approved Use

Galanium™ zinc lactate is a perfect solution to eliminate halitosis.
Inactive ingredient
Clean and Clear Advantage Acne Control Cleanser

Approved Use

Acne treatment
Curative
Unknown

Approved Use

Unknown
Primary
Unknown

Approved Use

Unknown
Primary
Crest Pro-Health Clinical Gum Protection Clean Mint Toothpaste

Approved Use

Anticavity, antigingivitis, antisensitivity toothpaste
PubMed

PubMed

TitleDatePubMed
Zinc salts inactivate clinical isolates of herpes simplex virus in vitro.
2000 May
Effect of different mouthrinses on morning breath.
2001 Sep
Dietary zinc deficiency reduced growth performance, intestinal immune and physical barrier functions related to NF-κB, TOR, Nrf2, JNK and MLCK signaling pathway of young grass carp (Ctenopharyngodon idella).
2017 Jul
Patents

Sample Use Guides

The volunteer rinsed with pre-procedural mouthwash containing 0.075% cetylpyridinium chloride, 0.28% zinc lactate and 0.05% sodium fluoride in an Alcohol-free base for one minute, 20 ml of solution and then expectorated all remaining liquid.
Route of Administration: Dental
Of 10 randomly chosen clinical isolates of herpes simplex virus (five HSV type 1 [HSV-1] isolates and five HSV-2 isolates), nine were inactivated >97% by treatment with zinc lactate. The effect was concentration dependent. With an HSV-1 isolate, 50 mM zinc lactate caused 100% inactivation, 15 mM caused 98 to 99% inactivation, and 5 mM caused 63 to 86% inactivation. With an HSV-2 isolate, 50 and 15 mM zinc lactate caused greater than 92% inactivation and 5 and 1 mM caused 37 and 26% inactivation, respectively.
Name Type Language
ZINC L-LACTATE
Common Name English
PROPANOIC ACID, 2-HYDROXY-, ZINC COMPLEX, (S)-
Systematic Name English
ZINC, BIS((2S)-2-(HYDROXY-.KAPPA.O)PROPANOATO-.KAPPA.O)-, (T-4)-
Systematic Name English
ZINC, BIS(2-HYDROXYPROPANOATO-O1,O2)-, (T-4-(S),(S))-
Systematic Name English
Code System Code Type Description
FDA UNII
323TLL3AFZ
Created by admin on Sat Dec 16 09:34:05 GMT 2023 , Edited by admin on Sat Dec 16 09:34:05 GMT 2023
PRIMARY
CAS
63179-81-7
Created by admin on Sat Dec 16 09:34:05 GMT 2023 , Edited by admin on Sat Dec 16 09:34:05 GMT 2023
PRIMARY
PUBCHEM
91667767
Created by admin on Sat Dec 16 09:34:05 GMT 2023 , Edited by admin on Sat Dec 16 09:34:05 GMT 2023
PRIMARY