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Details

Stereochemistry ABSOLUTE
Molecular Formula 2C3H5O3.Zn
Molecular Weight 243.549
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ZINC L-LACTATE

SMILES

[Zn++].C[C@H]([O-])C(O)=O.C[C@H]([O-])C(O)=O

InChI

InChIKey=UHKOOGWQCULNGT-CEOVSRFSSA-N
InChI=1S/2C3H5O3.Zn/c2*1-2(4)3(5)6;/h2*2H,1H3,(H,5,6);/q2*-1;+2/t2*2-;/m00./s1

HIDE SMILES / InChI

Description

Zinc lactate is used to eliminate halitosis. Halitosis (commonly known as bad breath) is a condition affecting many people and one of the most usual reasons why people go look for a dentist’s advice. The main origin of halitosis is related to the volatile sulphur compounds (VSC) produced by the different bacterial colonies found on the tongue and in the gingival crevices. Zinc lactate is a very effective solution to neutralize the VSC and an excellent ingredient for mouthwashes and toothpastes.

Approval Year

Targets

Primary TargetPharmacologyConditionPotency

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Galanium zinc lactate
Inactive ingredient
Clean and Clear Advantage Acne Control Cleanser
Curative
Unknown
Primary
Unknown
Primary
Crest Pro-Health Clinical Gum Protection Clean Mint Toothpaste

PubMed

Sample Use Guides

In Vivo Use Guide
The volunteer rinsed with pre-procedural mouthwash containing 0.075% cetylpyridinium chloride, 0.28% zinc lactate and 0.05% sodium fluoride in an Alcohol-free base for one minute, 20 ml of solution and then expectorated all remaining liquid.
Route of Administration: Dental
In Vitro Use Guide
Of 10 randomly chosen clinical isolates of herpes simplex virus (five HSV type 1 [HSV-1] isolates and five HSV-2 isolates), nine were inactivated >97% by treatment with zinc lactate. The effect was concentration dependent. With an HSV-1 isolate, 50 mM zinc lactate caused 100% inactivation, 15 mM caused 98 to 99% inactivation, and 5 mM caused 63 to 86% inactivation. With an HSV-2 isolate, 50 and 15 mM zinc lactate caused greater than 92% inactivation and 5 and 1 mM caused 37 and 26% inactivation, respectively.