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Showing 1 - 10 of 88 results

Status:
US Approved Rx (2013)
First approved in 2001

Class (Stereo):
CHEMICAL (ACHIRAL)



Zoledronic acid (Reclast, Aclasta, Zometa) is an intravenous, highly potent amino-bisphosphonate approved worldwide, including in the USA, EU and Japan for use in patients with primary or secondary osteoporosis or low bone mass (approved indications ...
Status:
US Approved Rx (2006)
First approved in 2000

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Zonisamide is an antiseizure drug chemically classified as a sulfonamide and unrelated to other antiseizure agents. The precise mechanism by which zonisamide exerts its antiseizure effect is unknown, although it is believed that the drug blocks sodiu...
Status:
US Approved Rx (2020)
First approved in 1998

Class (Stereo):
CHEMICAL (ABSOLUTE)



Brinzolamide reduces the amount of fluid in the eye, which decreases pressure inside the eye. Brinzolamide is a carbonic anhydrase inhibitor that is FDA approved for the treatment of elevated intraocular pressure in patients with ocular hypertension ...
Status:
US Approved Rx (2021)
First approved in 1997

Class (Stereo):
CHEMICAL (ABSOLUTE)



Pramipexole is a nonergot dopamine agonist with high relative in vitro specificity and full intrinsic activity at the D2 subfamily of dopamine receptors, binding with higher affinity to D3 than to D2 or D4 receptor subtypes. The relevance of D3 recep...
Status:
US Approved Rx (2009)
First approved in 1996

Class (Stereo):
CHEMICAL (ABSOLUTE)



Topiramate is an anticonvulsant indicated in the treatment of epilepsy and migraine. Topiramate enhances GABA-activated chloride channels. In addition, topiramate inhibits excitatory neurotransmission, through actions on kainate and AMPA receptors. T...
Status:
US Approved Rx (2019)
First approved in 1994

Class (Stereo):
CHEMICAL (ABSOLUTE)



Dorzolamide is a sulfonamide and a highly specific carbonic anhydrase II (CA-II) inhibitor, which is the main CA isoenzyme involved in aqueous humor secretion. Dorzolamide is marketed under the trade name Trusopt, indicated in the treatment of elevat...
Status:
US Approved Rx (2018)
First approved in 1959

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Methazolamide is topical carbonic anhydrase inhibitor. Methazolamide is indicated for the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension who are insufficiently responsive to beta-blockers. Metha...
Status:
US Approved Rx (2011)
First approved in 1958

Class (Stereo):
CHEMICAL (ACHIRAL)



Like other thiazides, chlorothiazide promotes water loss from the body (diuretics). It inhibits Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazid...
Status:
US Approved Rx (2023)
First approved in 1953

Class (Stereo):
CHEMICAL (ACHIRAL)



Acetazolamide, usually sold under the trade name Diamox in some countries. DIAMOX is used for adjunctive treatment of: chronic simple (open-angle) glaucoma, secondary glaucoma, and preoperatively in acute angle-closure glaucoma where delay of surgery...
Status:
US Approved Rx (1969)
First approved in 1948

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Mafenide is a sulfonamide-type medication used as an antibiotic. It is indicated for use as an adjunctive topical antimicrobial agent to control bacterial infection when used under moist dressings over meshed autografts on excised burn wounds. Mafeni...