U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 21 - 30 of 85 results

Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

QUCHIC or BB-22 (1-(cyclohexylmethyl)-8-quinolinyl ester-1H-indole-3-carboxylic acid), a quinoline derivative, is a synthetic cannabinoid. It is considered to be a constituent of illicit smoking mixtures "spice".
Status:
Other

Class (Stereo):
CHEMICAL (RACEMIC)


Conditions:

UR-144 N(4-hydroxypentyl) is a potent synthetic cannabinoid designed by Abbott Laboratories as a CB2 selective agonist for pain management. UR-144 N(4-hydroxypentyl) is a metabolite of another CB2-selective cannabinoid UR-144. Pre-clinical studies of nociceptive and neuropathic pain have shown that CB2-selective ligands are analgesics without causing the adverse side effects linked with CB1 receptor activation. However, nor UR-144 nor UR-144 N(4-hydroxypentyl) has no therapeutic application.
Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

UR-144 N-5-Hydroxypentyl is a potent synthetic cannabinoid designed by Abbott Laboratories as a CB2 selective agonist for pain management. UR-144 N-5-Hydroxypentyl is a metabolite of another CB2-selective cannabinoid UR-144. Pre-clinical studies of nociceptive and neuropathic pain have shown that CB2-selective ligands are analgesics without causing the adverse side effects linked with CB1 receptor activation. However, nor UR-144 nor UR-144 N-5-Hydroxypentyl has no therapeutic application.
Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

JWH-073, a synthetic cannabinoid, is an analgesic chemical from the naphthoylindole family that acts as a neutral antagonist of CB1 cannabioid receptor and binder of CB2 cannabinoid receptor. JWH-073 is being used as a recreational drug in Spice products, and is a controlled substance in USA.