Details
Stereochemistry | ACHIRAL |
Molecular Formula | C21H22BrNO |
Molecular Weight | 384.309 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CCCCCN1C=C(C(=O)CC2=C(Br)C=CC=C2)C3=C1C=CC=C3
InChI
InChIKey=CGQRVOHECAULLB-UHFFFAOYSA-N
InChI=1S/C21H22BrNO/c1-2-3-8-13-23-15-18(17-10-5-7-12-20(17)23)21(24)14-16-9-4-6-11-19(16)22/h4-7,9-12,15H,2-3,8,13-14H2,1H3
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
---|---|---|---|
Target ID: CHEMBL253 Sources: https://www.ncbi.nlm.nih.gov/pubmed/16005223 |
20.0 nM [Ki] | ||
Target ID: CHEMBL3571 Sources: https://www.ncbi.nlm.nih.gov/pubmed/16005223 |
8.0 nM [IC50] |
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WIKIPEDIA |
Designer-drugs-JWH-249
Created by
admin on Sat Dec 16 11:17:34 GMT 2023 , Edited by admin on Sat Dec 16 11:17:34 GMT 2023
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Code System | Code | Type | Description | ||
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864445-60-3
Created by
admin on Sat Dec 16 11:17:34 GMT 2023 , Edited by admin on Sat Dec 16 11:17:34 GMT 2023
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44397335
Created by
admin on Sat Dec 16 11:17:34 GMT 2023 , Edited by admin on Sat Dec 16 11:17:34 GMT 2023
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JWH-249
Created by
admin on Sat Dec 16 11:17:34 GMT 2023 , Edited by admin on Sat Dec 16 11:17:34 GMT 2023
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PRIMARY | JWH-249 (1-pentyl-3-(2-bromophenylacetyl)indole) is a synthetic cannabinoid from the phenylacetylindole family, which acts as a cannabinoid agonist with about 2.4x selectivity for CB1 with a Ki of 8.4nM +/- 1.8 and 20nM +/- 2 at CB2. Similar to the related 2'-methoxy compound JWH-250, the 2'-chloro compound JWH-203, and the 2'-methyl compound JWH-251, JWH-249 has a phenylacetyl group in place of the naphthoyl ring used in most aminoalkylindole cannabinoid compounds. | ||
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DTXSID30658735
Created by
admin on Sat Dec 16 11:17:34 GMT 2023 , Edited by admin on Sat Dec 16 11:17:34 GMT 2023
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H988KQV4U9
Created by
admin on Sat Dec 16 11:17:34 GMT 2023 , Edited by admin on Sat Dec 16 11:17:34 GMT 2023
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PRIMARY |
ACTIVE MOIETY