QUCHIC

Details

Stereochemistry	ACHIRAL
Molecular Formula	C25H24N2O2
Molecular Weight	384.4703
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

O=C(OC1=C2N=CC=CC2=CC=C1)C3=CN(CC4CCCCC4)C5=C3C=CC=C5

InChI

InChIKey=RHYGTJXOHOGQGI-UHFFFAOYSA-N

InChI=1S/C25H24N2O2/c28-25(29-23-14-6-10-19-11-7-15-26-24(19)23)21-17-27(16-18-8-2-1-3-9-18)22-13-5-4-12-20(21)22/h4-7,10-15,17-18H,1-3,8-9,16H2

HIDE SMILES / InChI

Molecular Formula	C25H24N2O2
Molecular Weight	384.4703
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/27429655 | https://www.caymanchem.com/product/14099

QUCHIC or BB-22 (1-(cyclohexylmethyl)-8-quinolinyl ester-1H-indole-3-carboxylic acid), a quinoline derivative, is a synthetic cannabinoid. It is considered to be a constituent of illicit smoking mixtures "spice".

CNS Activity

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Cannabinoid CB1 receptor 85 Target ID: CHEMBL218 Sources: https://www.ncbi.nlm.nih.gov/pubmed/27429655	Agonist 2752		0.338 nM [Ki]
Cannabinoid CB2 receptor 71 Target ID: CHEMBL253 Sources: https://www.ncbi.nlm.nih.gov/pubmed/27429655	Agonist 2752		0.217 nM [Ki]

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2596

PubMed

Title	Date	PubMed
Pharmacological evaluation of synthetic cannabinoids identified as constituents of spice.	2016	27429655

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Tue Apr 01 16:25:20 GMT 2025` Edited by `admin` on `Tue Apr 01 16:25:20 GMT 2025`
Record UNII	EUD4ZLB25R
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

QUCHIC

Common Name

English

J3.293.456K

Preferred Name

English

QUINOLIN-8-YL 1-(CYCLOHEXYLMETHYL)-1H-INDOLE-3-CARBOXYLATE

Systematic Name

English

1H-INDOLE-3-CARBOXYLIC ACID, 1-(CYCLOHEXYLMETHYL)-, 8-QUINOLINYL ESTER

Systematic Name

English

1-(CYCLOHEXYLMETHYL)-1H-INDOLE-3-CARBOXYLIC ACID QUINOLINE-8-YL ESTER

Systematic Name

English

BB-22

Common Name

English

Classification Tree Code System Code

WIKIPEDIA

Designer-drugs-BB-22