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Details

Stereochemistry ACHIRAL
Molecular Formula C21H23NO
Molecular Weight 305.4134
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of JWH-167

SMILES

CCCCCN1C=C(C(=O)CC2=CC=CC=C2)C3=C1C=CC=C3

InChI

InChIKey=AMCPOEOUXQWESI-UHFFFAOYSA-N
InChI=1S/C21H23NO/c1-2-3-9-14-22-16-19(18-12-7-8-13-20(18)22)21(23)15-17-10-5-4-6-11-17/h4-8,10-13,16H,2-3,9,14-15H2,1H3

HIDE SMILES / InChI

Molecular Formula C21H23NO
Molecular Weight 305.4134
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
90.0 nM [Ki]
Target ID: P34972
Gene ID: 1269.0
Gene Symbol: CNR2
Target Organism: Homo sapiens (Human)
159.0 nM [Ki]
Substance Class Chemical
Created
by admin
on Sat Dec 16 11:17:34 GMT 2023
Edited
by admin
on Sat Dec 16 11:17:34 GMT 2023
Record UNII
LQX1W3537N
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
JWH-167
Code English
2-PHENYL-1-(1-PENTYLINDOL-3-YL)ETHANONE
Systematic Name English
ETHANONE, 1-(1-PENTYL-1H-INDOL-3-YL)-2-PHENYL-
Systematic Name English
JWH 167
Code English
1-(1-PENTYL-1H-INDOL-3-YL)-2-PHENYLETHANONE
Systematic Name English
Classification Tree Code System Code
WIKIPEDIA Designer-drugs-JWH-167
Created by admin on Sat Dec 16 11:17:34 GMT 2023 , Edited by admin on Sat Dec 16 11:17:34 GMT 2023
Code System Code Type Description
CAS
864445-37-4
Created by admin on Sat Dec 16 11:17:34 GMT 2023 , Edited by admin on Sat Dec 16 11:17:34 GMT 2023
PRIMARY
EPA CompTox
DTXSID20235554
Created by admin on Sat Dec 16 11:17:34 GMT 2023 , Edited by admin on Sat Dec 16 11:17:34 GMT 2023
PRIMARY
FDA UNII
LQX1W3537N
Created by admin on Sat Dec 16 11:17:34 GMT 2023 , Edited by admin on Sat Dec 16 11:17:34 GMT 2023
PRIMARY
PUBCHEM
44397502
Created by admin on Sat Dec 16 11:17:34 GMT 2023 , Edited by admin on Sat Dec 16 11:17:34 GMT 2023
PRIMARY
WIKIPEDIA
JWH-167
Created by admin on Sat Dec 16 11:17:34 GMT 2023 , Edited by admin on Sat Dec 16 11:17:34 GMT 2023
PRIMARY JWH-167 (1-pentyl-3-(phenylacetyl)indole) is a synthetic cannabinoid from the phenylacetylindole family, which acts as a cannabinoid agonist with about 1.75x selectivity for CB1 with a Ki of 90nM +/- 17 and 159nM +/- 14 at CB2. Similar to the related 2'-methoxy compound JWH-250, and the 2'-chloro compound JWH-203, JWH-167 has a phenylacetyl group in place of the naphthoyl ring used in most aminoalkylindole cannabinoid compounds.
MANUFACTURER PRODUCT INFORMATION
JWH-167
Created by admin on Sat Dec 16 11:17:34 GMT 2023 , Edited by admin on Sat Dec 16 11:17:34 GMT 2023
PRIMARY JWH 167 is a synthetic cannabinoid (CB) with moderate affinities for both central CB1 (Ki = 90 nM) and peripheral CB2 (Ki = 159 nM) receptors.1 Its physiological and toxicological properties are not known. This product is intended for forensic and research purposes.
Related Record Type Details
ACTIVE MOIETY