JWH-412

CCCCCN1C=C(C(=O)C2=C3C=CC=CC3=C(F)C=C2)C4=C1C=CC=C4

InChIKey=HDWMKVHXWFNFQW-UHFFFAOYSA-N

InChI=1S/C24H22FNO/c1-2-3-8-15-26-16-21(19-11-6-7-12-23(19)26)24(27)20-13-14-22(25)18-10-5-4-9-17(18)20/h4-7,9-14,16H,2-3,8,15H2,1H3

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Condition	Potency
Cannabinoid CB2 receptor 71 Target ID: CHEMBL253 Sources: https://www.ncbi.nlm.nih.gov/pubmed/22341572 \| https://www.unodc.org/documents/scientific/STNAR48_Synthetic_Cannabinoids_ENG.pdf \| https://tigerprints.clemson.edu/cgi/viewcontent.cgi?referer=https://www.google.ru/&httpsredir=1&article=1253&context=all_dissertations	Agonist 2678		3.2 nM [Ki]
Cannabinoid CB1 receptor 85 Target ID: CHEMBL218 Sources: https://www.ncbi.nlm.nih.gov/pubmed/22341572 \| https://www.unodc.org/documents/scientific/STNAR48_Synthetic_Cannabinoids_ENG.pdf \| https://tigerprints.clemson.edu/cgi/viewcontent.cgi?referer=https://www.google.ru/&httpsredir=1&article=1253&context=all_dissertations	Agonist 2678		7.2 nM [Ki]

PubMed

Title	Date	PubMed
Separation and structural characterization of the synthetic cannabinoids JWH-412 and 1-[(5-fluoropentyl)-1H-indol-3yl]-(4-methylnaphthalen-1-yl)methanone using GC-MS, NMR analysis and a flash chromatography system.	2012 Jul 10	22264627
Synthesis and pharmacology of 1-alkyl-3-(1-naphthoyl)indoles: steric and electronic effects of 4- and 8-halogenated naphthoyl substituents.	2012 Mar 15	22341572

Substance Class	Chemical Created by `admin` on `Sat Dec 16 11:17:22 GMT 2023` Edited by `admin` on `Sat Dec 16 11:17:22 GMT 2023`
Record UNII	PCX2678XVD
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

JWH-412

Code

English

METHANONE, (4-FLUORO-1-NAPHTHALENYL)(1-PENTYL-1H-INDOL-3-YL)-

Systematic Name

English

(4-FLUORONAPHTHALEN-1-YL)(1-PENTYL-1H-INDOL-3-YL)METHANONE

Systematic Name

English

Code System Code Type Description

FDA UNII

PCX2678XVD

Created by admin on Sat Dec 16 11:17:22 GMT 2023 , Edited by admin on Sat Dec 16 11:17:22 GMT 2023

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PUBCHEM

71454236

Created by admin on Sat Dec 16 11:17:22 GMT 2023 , Edited by admin on Sat Dec 16 11:17:22 GMT 2023

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EPA CompTox

DTXSID10101000

Created by admin on Sat Dec 16 11:17:22 GMT 2023 , Edited by admin on Sat Dec 16 11:17:22 GMT 2023

PRIMARY

CAS

1364933-59-4

Created by admin on Sat Dec 16 11:17:22 GMT 2023 , Edited by admin on Sat Dec 16 11:17:22 GMT 2023

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