Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
α-Solanine is a glycoalkaloid found in species of the nightshade family including potato. The name is derived from the Latin for European black nightshade (Solanum nigrum), from which solanine was first isolated in 1820. It was primarily reported to ...
Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Chelidonine is the major alkaloid component of Chelidonium majus. Chelidonine is an isolate of Papaveraceae with acetylcholinesterase and butyrylcholinesterase (a nonspecific cholinesterase) inhibitory activity. It showed strong cytotoxicity in cance...
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Tacrine is a parasympathomimetic- a reversible cholinesterase inhibitor that is indicated for the treatment of mild to moderate dementia of the Alzheimer's type. An early pathophysiological feature of Alzheimer's disease that is associated with memor...
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Chloranil is an oxidant, practically useful for dehydrogenation to aromatic and alpha,beta-desaturated carbonyl compounds. Chloranil was found to inhibit human carboxylesterases: carboxylesterase 1 and 2, acetylcholinesterase and butyrylcholinesteras...
Class (Stereo):
CHEMICAL (RACEMIC)
Conditions:
Ethopropazine is an anticholinergic drug. Ethopropazine is an inhibitor of butyrylcholinesterase and non-selective muscarinic acetylcholine receptor antagonist. Ethopropazine has been used for the treatment of parkinsonism and drug-induced extrapyram...
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Edrophonium is a short and rapid-acting cholinergic drug. Chemically, edrophonium is ethyl (m-hydroxyphenyl) dimethylammonium. Edrophonium is used for the differential diagnosis of myasthenia gravis and as an adjunct in the evaluation of treatment re...
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Dichlorvos is a synthetic organic chemical used as an insecticide. Dichlorvos does not occur naturally in the environment, but is manufactured by industry. Dichlorvos is sold under many trade names including Vapona®, Atgard®, Nuvan®, and Task®. It is...
Class (Stereo):
CHEMICAL (RACEMIC)
Targets:
Trichlorfon (Metrifonate), the organophosphorous cholinesterase inhibitor, O,O-dimethylhydroxy-2,2,2-trichlorethyl-phosphonate, has been used sporadically in the treatment of human schistosomiasis for a decade. It has selective and variable schistoso...
Class (Stereo):
CHEMICAL (RACEMIC)
Bambuterol is an active precursor of the selective beta2-adrenergic agonist terbutaline. Bambuterol is the bis-N,N-dimethyl-carbamate of terbutaline.
Bambuterol is a remarkably selective and potent inhibitor of cholinesterase. BAMBEC (Bambuterol hydr...
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Dimebon (latrepirdine) is an orally available, small molecule, gamma carboline derivative that was developed and used in Russia as an over-the-counter oral antihistamine for allergy treatment since 1980s. In 1990s it was shown that Dimebon has promi...