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Showing 1 - 10 of 150 results

Status:
US Approved Rx (2016)
First approved in 2011

Class (Stereo):
CHEMICAL (ABSOLUTE)



Linagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor discovered by Boehringer Ingelheim and being developed as an oral once-daily tablet for the treatment of Type 2 diabetes. Linagliptin was first approved by FDA in 2011 under the trade name Tra...
Status:
US Approved Rx (2022)
First approved in 2008

Class (Stereo):
CHEMICAL (ACHIRAL)

Targets:


Bendamustine, brand name Treanda, is a chemotherapeutic agent that displays a unique pattern of cytotoxicity compared with conventional alkylating agents. Treanda is indicated for the treatment of patients with chronic lymphocytic leukemia (CLL), in ...
Status:
US Approved Rx (2010)
First approved in 1995

Class (Stereo):
CHEMICAL (ACHIRAL)



Losartan is a selective, competitive angiotensin II receptor type 1 (AT1) antagonist. Losartant is recommended as one of several preferred agents for the initial management of hypertension. Administration of losartan reduces the risk of stroke in pat...
Status:
US Approved Rx (2003)
First approved in 1993

Class (Stereo):
CHEMICAL (ACHIRAL)



Torasemide is a pyridine-sulfonylurea type loop diuretic mainly used for the treatment of edema associated with congestive heart failure, renal disease, or hepatic disease. Also for the treatment of hypertension alone or in combination with other ant...
Status:
US Approved Rx (2000)
First approved in 1993

Class (Stereo):
CHEMICAL (ABSOLUTE)



Cladribine is used for the treatment of hairy cell leukemia and multiple sclerosis (MS). As a purine analog, it is a synthetic anti-cancer agent that also suppresses the immune system. Chemically, it mimics the nucleoside adenosine and thus inhibits ...
Status:
US Approved Rx (2008)
First approved in 1991

Class (Stereo):
CHEMICAL (ABSOLUTE)



Pravastatin (marketed as Pravachol or Selektine) is a member of the drug class of statins, used in combination with diet, exercise, and weight loss for lowering cholesterol and preventing cardiovascular disease. Pravastatin acts as a lipoprotein-lowe...
Status:
US Approved Rx (2018)
First approved in 1991

Class (Stereo):
CHEMICAL (ABSOLUTE)



Azithromycin is one of the world's best-selling antibiotics, used to treat or prevent certain bacterial infections: Acute bacterial exacerbations of chronic bronchitis in adults; acute bacterial sinusitis in adults; uncomplicated skin and skin struct...
Status:
US Approved Rx (2007)
First approved in 1987

Class (Stereo):
CHEMICAL (ABSOLUTE)



Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI) with activity against Human Immunodeficiency Virus Type 1 (HIV-1). Zidovudine is phosphorylated to active metabolites that compete for incorporation into viral DNA. They inhibit the HI...
Status:
US Approved Rx (1993)
First approved in 1986

Class (Stereo):
CHEMICAL (ABSOLUTE)



Dexketoprofen is a nonsteroidal anti-inflammatory drug (NSAID), manufactured by Menarini under the tradename Keral. Dexketoprofen is indicated for short-term treatment of mild to moderate pain, including dysmenorrhoea. Dexketoprofen works by blockin...
Status:
US Approved Rx (2025)
First approved in 1983

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Bumetanide is indicated for the treatment of edema associated with congestive heart failure, hepatic and renal disease, including the nephrotic syndrome. It blocks the reabsorption of sodium and fluid from the kidney's tubules. The most frequent clin...