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Development Status

US Approved OTC

2

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Primary Target

Transient receptor potential cation channel subfamily A member 1

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Transient receptor potential cation channel subfamily V member 3

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Vanilloid receptor

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Highest Phase

Approved

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Approval Year

1921

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Cough

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Muscle pain

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Pain

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Palliative

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Primary

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CNS Penetrant

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CHEBI

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ATC Level 3

OTHER CARDIAC PREPARATIONS

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ATC Level 4

Other cardiac preparations

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Salts, Hydrates, Esters, etc.

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CAMPHOR (NATURAL)

N20HL7Q941

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Status:

US Approved OTC

First marketed in 1921

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

Vanilloid receptor

Transient receptor potential cation channel subfamily A member 1

Transient receptor potential cation channel subfamily V member 3

Conditions:

Camphor is a bicyclic monoterpene ketone found widely in plants, especially cinnamomum camphora. Topically, camphor is used to relieve pain. It has been used to treat warts, cold sores, hemorrhoids, and osteoarthritis. It has also been applied topica...

lly as an analgesic and an antipruritic. It has been used as a counterirritant, and to increase local blood flow. Camphor has frequently been used topically to treat respiratory tract diseases involving mucous membrane inflammation. It is sometimes used topically to treat cardiac symptoms. Camphor is also used topically as an eardrop, and for treating minor burns. In inhalation therapy, camphor is used as an antitussive. Orally, camphor is used as an expectorant, antiflatulent, and for treating respiratory tract diseases. Today, most camphor is synthetic. It is approved by the FDA as a topical antitussive. Camphor is produced synthetically from the oil of turpentine. It has been used for centuries for its medicinal features, in religious rituals, and in cooking. It is no longer used as pesticide. In 1982, the US Food and Drug Administration restricted commercial products intended for medicinal use to contain <11% camphor.

CAMPHOR (SYNTHETIC)

5TJD82A1ET

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Status:

US Approved OTC

First marketed in 1921

Class (Stereo):

CHEMICAL (RACEMIC)

Targets:

Vanilloid receptor

Transient receptor potential cation channel subfamily A member 1

Transient receptor potential cation channel subfamily V member 3

Conditions:

Camphor is a bicyclic monoterpene ketone found widely in plants, especially cinnamomum camphora. Topically, camphor is used to relieve pain. It has been used to treat warts, cold sores, hemorrhoids, and osteoarthritis. It has also been applied topica...

lly as an analgesic and an antipruritic. It has been used as a counterirritant, and to increase local blood flow. Camphor has frequently been used topically to treat respiratory tract diseases involving mucous membrane inflammation. It is sometimes used topically to treat cardiac symptoms. Camphor is also used topically as an eardrop, and for treating minor burns. In inhalation therapy, camphor is used as an antitussive. Orally, camphor is used as an expectorant, antiflatulent, and for treating respiratory tract diseases. Today, most camphor is synthetic. It is approved by the FDA as a topical antitussive. Camphor is produced synthetically from the oil of turpentine. It has been used for centuries for its medicinal features, in religious rituals, and in cooking. It is no longer used as pesticide. In 1982, the US Food and Drug Administration restricted commercial products intended for medicinal use to contain <11% camphor.

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