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Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Tianafac (also known as L8109) is a thienylacetic acid derivative patented by Labaz group as antipyretics and anti-inflammatory agent useful for the treatment of arthritis. In preclinical models, Tianafac inhibits prostaglandin formation by seminal vesicle microsomes and exerts antipyretic, analgetic, and moderate gastric ulcerogenic activity and had a wide safety margin between toxic and pharmacologically active doses.
Class (Stereo):
CHEMICAL (ACHIRAL)
Pipoxizine is the antihistamine agent and antiserotonin agent. It was used as antiarrhythmic and bronchodilator.
Class (Stereo):
CHEMICAL (RACEMIC)
Camiverine is phenylacetate derivative with cardio-vascular. Its antispasmodic action was 1/16 that of atropine (for the acetylcholine spasm) and 6.7-19.4 times that of papaverine for the BaCl2 and the histamine spasm, both tests in vitro. No chronic toxicity was observed for the oral dose of 50-100 mg/kg daily for 60 days in rats.
Status:
Investigational
Source:
INN:cinnofuradione [INN]
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
Cinnofuradione is a cinnoline derivative with analgesic properties. It was patented in 1954 and was claimed to be useful in combatting inflammation and rheumatism.
Class (Stereo):
CHEMICAL (ACHIRAL)
Amiquinsin hydrochloride, 4-amino-6,7-dimethoxquinoline hydrochloride hydrate, is a drug, which exhibits hypotensive activity. Amiquinsin has a more prolonged hypotensive effect than the hydroxyquinoline.
Status:
Investigational
Class (Stereo):
CHEMICAL (RACEMIC)
Tixadil is a coronary vasodilator and sedative agent.
Class (Stereo):
CHEMICAL (RACEMIC)
Conditions:
There is no information about pharmacological and biological properties of epicainide. It is known, that drug was a potent antiarrhythmic agent.
Status:
Investigational
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Investigational
Class (Stereo):
CHEMICAL (ACHIRAL)
Symetine is a benzylamine derivative patented by Eli Lilly & Co. as an antiparasitic and antispirochete agent. In preclinical models, Symetine effectively suppresses amebic liver abscess in guinea pigs.
Class (Stereo):
CHEMICAL (ACHIRAL)
Sulicrinat (also known as HOE 428) is a sulfamoylbenzophenone derivative patented by Hoechst A.-G. as a loop diuretic.