CAMIVERINE

Details

Stereochemistry	RACEMIC
Molecular Formula	C19H30N2O2
Molecular Weight	318.4537
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)CCOC(=O)C(NCCN1CCCC1)C2=CC=CC=C2

InChI

InChIKey=HKVGEMSALZULPM-UHFFFAOYSA-N

InChI=1S/C19H30N2O2/c1-16(2)10-15-23-19(22)18(17-8-4-3-5-9-17)20-11-14-21-12-6-7-13-21/h3-5,8-9,16,18,20H,6-7,10-15H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C19H30N2O2
Molecular Weight	318.4537
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://onlinelibrary.wiley.com/doi/abs/10.1111/j.2042-7158.1960.tb12650.x | Archivio Italiano di Scienze Farmacologiche (1959), 9, 142-3.

Camiverine is phenylacetate derivative with cardio-vascular. Its antispasmodic action was 1/16 that of atropine (for the acetylcholine spasm) and 6.7-19.4 times that of papaverine for the BaCl2 and the histamine spasm, both tests in vitro. No chronic toxicity was observed for the oral dose of 50-100 mg/kg daily for 60 days in rats.

Approval Year

Patents

Sample Use Guides

In Vivo Use Guide

50-100 mg./kg

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Sat Dec 16 17:37:58 GMT 2023` Edited by `admin` on `Sat Dec 16 17:37:58 GMT 2023`
Record UNII	S5D373PRDG
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CAMIVERINE

Official Name

English

camiverine [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C66880