SYMETINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C30H48N2O2
Molecular Weight	468.7143
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCCCCN(C)CC1=CC=C(OCCOC2=CC=C(CN(C)CCCCCC)C=C2)C=C1

InChI

InChIKey=XVGLWUPIJXJSOB-UHFFFAOYSA-N

InChI=1S/C30H48N2O2/c1-5-7-9-11-21-31(3)25-27-13-17-29(18-14-27)33-23-24-34-30-19-15-28(16-20-30)26-32(4)22-12-10-8-6-2/h13-20H,5-12,21-26H2,1-4H3

HIDE SMILES / InChI

Molecular Formula	C30H48N2O2
Molecular Weight	468.7143
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/15445946 | https://www.ncbi.nlm.nih.gov/pubmed/24543175 | Antibiotics and Chemotherapy (Washington, D. C.) (1954), 4, 753-62.

Symetine is a benzylamine derivative patented by Eli Lilly & Co. as an antiparasitic and antispirochete agent. In preclinical models, Symetine effectively suppresses amebic liver abscess in guinea pigs.

Originator

Approval Year

PubMed

Title	Date	PubMed
Symetine hydrochloride in the treatment of amebic liver abscess in guinea pigs.	1963 Mar	15445946

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 16:55:51 GMT 2023` Edited by `admin` on `Sat Dec 16 16:55:51 GMT 2023`
Record UNII	UZ8WTY8051
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

SYMETINE

Official Name

English

L-16726

Code

English

4,4'-(ETHYLENEDIOXY)BIS(N-HEXYL-N-METHYLBENZYLAMINE)

Systematic Name

English

BENZENEMETHANAMINE, 4,4'-(1,2-ETHANEDIYLBIS(OXY)BIS(N-HEXYL-N-METHYL-

Common Name

English

symetine [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C277