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Originator

Domenjoz, R.

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Pfizer

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Eli Lilly

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Merck

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GlaxoSmithKline

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US Approved Rx

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Approved

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Approval Year

1949

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Condition

Pruritus

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Scabies

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Unknown

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Curative

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Palliative

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Chemical

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CAS

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FDA UNII

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PUBCHEM

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CHEBI

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ChEMBL

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Salts, Hydrates, Esters, etc.

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CROTAMITON, (E)-

2EEH27851Y

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Status:

US Approved Rx (1981)

First approved in 1949

Class (Stereo):

CHEMICAL (ACHIRAL)

Conditions:

Crotamiton is a scabicidal and antipruritic agent available as a cream or lotion for topical use. The drug was approved by FDA for the treatment of scabies and pruritic skin. Crotamiton is a mixture of the cis and trans isomers of N-ethyl-N-(o-methyl...

phenyl)-2butenamide. Although the activity of crotamiton was shown both in vitro and in vivo, the mechanism of its action is still unknown.

CROTAMITON, (Z)-

RG5JA2O40Z

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Status:

US Approved Rx (1981)

First approved in 1949

Class (Stereo):

CHEMICAL (ACHIRAL)

Conditions:

Crotamiton is a scabicidal and antipruritic agent available as a cream or lotion for topical use. The drug was approved by FDA for the treatment of scabies and pruritic skin. Crotamiton is a mixture of the cis and trans isomers of N-ethyl-N-(o-methyl...

phenyl)-2butenamide. Although the activity of crotamiton was shown both in vitro and in vivo, the mechanism of its action is still unknown.

CROTAMITON

D6S4O4XD0H

Status:

US Approved Rx (1981)

First approved in 1949

Class:

MIXTURE

Conditions:

Crotamiton is a scabicidal and antipruritic agent available as a cream or lotion for topical use. The drug was approved by FDA for the treatment of scabies and pruritic skin. Crotamiton is a mixture of the cis and trans isomers of N-ethyl-N-(o-methyl...

phenyl)-2butenamide. Although the activity of crotamiton was shown both in vitro and in vivo, the mechanism of its action is still unknown.

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