| Stereochemistry | ACHIRAL |
| Molecular Formula | C13H17NO |
| Molecular Weight | 203.2802 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 1 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCN(C(=O)\C=C\C)C1=C(C)C=CC=C1
InChI
InChIKey=DNTGGZPQPQTDQF-XBXARRHUSA-N
InChI=1S/C13H17NO/c1-4-8-13(15)14(5-2)12-10-7-6-9-11(12)3/h4,6-10H,5H2,1-3H3/b8-4+
Crotamiton is a scabicidal and antipruritic agent available as a cream or lotion for topical use. The drug was approved by FDA for the treatment of scabies and pruritic skin. Crotamiton is a mixture of the cis and trans isomers of N-ethyl-N-(o-methylphenyl)-2butenamide. Although the activity of crotamiton was shown both in vitro and in vivo, the mechanism of its action is still unknown.
Originator
Approval Year
PubMed
Patents
SUBSTANCE RECORD
