U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 2541 - 2550 of 13362 results

Aluminum Stearate (C54H105AlO6) exists as white powder and is an aluminum salt of stearic acid. In the pharmaceutical industry, it is used as an anticaking agent; colorant; emulsion stabilizer; and viscosity increasing agent. According to the FDA, aluminum stearate is considered safe for general or specific, limited use in food. Aluminum stearate is not classifiable as a human carcinogen (cancer-causing agent).
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (RACEMIC)

Calteridol is tetraazacyclododecane-1,4,7-triacetic acid derivative patented by Bracco and Dibra S.P.A.
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)

Steareth-2 is a surfactant. It is polyethylene glycol ethers of stearci acid. It is a waxy compound. In cosmetics and personal care products, Steareth ingredients are used in the formulation of personal cleanliness products and deodorants, as well as suntan, fragrance, skin, eye and hair products. Steareth-2 was nontoxic to rats in acute oral toxicity studies. Steareth-2 in water was neither primary irritants nor sensitizers to human skin.
Glabridin is an isoflavane found in the root extract of licorice (Glycyrrhiza glabra). Glabridin is considered to be a phytoestrogen and has been associated with numerous biological properties ranging from antioxidant, anti-inflammatory, neuroprotective, anti-atherogenic effects, to the regulation of energy metabolism, but also including anti-tumorigenic, anti-nephritic, antibacterial and skin-whitening activities. A glabridin-enriched extract is widely used in a cosmetic formulation as anti-inflammatory, antioxidant and skin whitening agent. Anti-inflammatory action of glabridin is linked to downregulation of NF-κB, AP-1 and MAPKS signaling. Glabridin-induced attenuation of atherosclerosis is related to a reduction in macrophages-associated oxidation of low-density lipoprotein.
Status:
Possibly Marketed Outside US
Source:
CFR:21 CFR 331.11
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Conditions:

Magnesium Tartrate is magnesium salt of tartaric acid
Status:
Possibly Marketed Outside US
Source:
NCT00483795: Phase 4 Interventional Completed Corneal Staining
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Aminomethylpropanol is a synthetic ingredient that functions as a buffer to adjust the pH of cosmetics and personal care products. In cosmetics and personal care products, aminomethylpropanol is used in the formulation of creams and lotions, hair sprays, wave sets, hair dyes and colors, eye and facial products, and other hair and skin care products. The main function of aminomethylpropanol in these products is to establish and hold the pH. The Food and Drug Administration (FDA) includes aminomethylpropanol on its list of indirect food additives as a component of adhesives that are in contact with food. The European Chemicals Agency (ECHA) identifies that “substance causes serious eye irritation, is harmful to aquatic life with long lasting effects and causes skin irritation, causes serious eye damage.” Toxicologically significant concentrations of AMP are unlikely to be achieved in the systemic circulation and/or target tissues in humans as a result of dermal application of products containing aminomethylpropanol. Systemically absorbed dose will be rapidly eliminated from the body with little remaining at the application site.
Status:
Possibly Marketed Outside US
Source:
Japan:Piperazine Adipate
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Adipic acid has been incorporated into controlled-release formulation matrix tablets to obtain a pH-independent release for both weakly basic and weakly acidic drugs. It has also been incorporated into the polymeric coating of hydrophilic monolithic systems to modulate the intragel pH, resulting in zero-order release of hydrophilic drugs. The disintegration at intestinal pH of the enteric polymer shellac has been reported to improve when adipic acid was used as a pore-forming agent without affecting release in the acidic media. Adipic acid is used to make bisobrin an antifibrinolytic.

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Glycol distereate is the diester of stearic acid and ethylene glycol. It is used in cosmetic products (creams, shampoos, moisturizers, soaps) because of its pearlescent, opacity and moisturizing effects as well as its high foaming capacity. It is also used as a food additive. There are no known safety concerns.

Showing 2541 - 2550 of 13362 results