Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C4H11NO |
| Molecular Weight | 89.1362 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(C)(N)CO
InChI
InChIKey=CBTVGIZVANVGBH-UHFFFAOYSA-N
InChI=1S/C4H11NO/c1-4(2,5)3-6/h6H,3,5H2,1-2H3
| Molecular Formula | C4H11NO |
| Molecular Weight | 89.1362 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Aminomethylpropanol is a synthetic ingredient that functions as a buffer to adjust the pH of cosmetics and personal care products. In cosmetics and personal care products, aminomethylpropanol is used in the formulation of creams and lotions, hair sprays, wave sets, hair dyes and colors, eye and facial products, and other hair and skin care products. The main function of aminomethylpropanol in these products is to establish and hold the pH. The Food and Drug Administration (FDA) includes aminomethylpropanol on its list of indirect food additives as a component of adhesives that are in contact with food. The European Chemicals Agency (ECHA) identifies that “substance causes serious eye irritation, is harmful to aquatic life with long lasting effects and causes skin irritation, causes serious eye damage.” Toxicologically significant concentrations of AMP are unlikely to be achieved in the systemic circulation and/or target tissues in humans as a result of dermal application of products containing aminomethylpropanol. Systemically absorbed dose will be rapidly eliminated from the body with little remaining at the application site.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Distinguishing between maternally-mediated and directly embryotoxic modes-of-action for postimplantation loss induced in rats by 2-amino-2-methylpropanol. | 2014-11 |
|
| Crystal structure and electronic properties of 2-amino-2-methyl-1-propanol (AMP) carbamate. | 2010-12-28 |
|
| Nucleophilicity and accessibility calculations of alkanolamines: applications to carbon dioxide absorption reactions. | 2010-12-16 |
|
| N-(2-Hy-droxy-1,1-dimethyl-eth-yl)-benzene-sulfonamide. | 2010-10-31 |
|
| Effects of shape, porosity, and operating parameters on carbon dioxide recovery in polytetrafluoroethylene membranes. | 2010-07-15 |
|
| Harmonization of values for serum alkaline phosphatase catalytic activity concentration employing commutable calibration materials. | 2010-06-03 |
|
| Intranasal delivery of influenza subunit vaccine formulated with GEM particles as an adjuvant. | 2010-06 |
|
| Estrogens attenuate oxidative stress and the differentiation and apoptosis of osteoblasts by DNA-binding-independent actions of the ERalpha. | 2010-04 |
|
| Evaluation of alkanolamine solutions for carbon dioxide removal in cross-flow rotating packed beds. | 2010-03-15 |
|
| Determination of calcium in synovial fluid samples as an aid to diagnosing osteoarthritis. | 2010-02 |
|
| Association of urinary bisphenol a concentration with heart disease: evidence from NHANES 2003/06. | 2010-01-13 |
|
| Capture of carbon dioxide by amine-impregnated as-synthesized MCM-41. | 2010 |
|
| Developmental and molecular physiological evidence for the role of phosphoenolpyruvate carboxylase in rapid cotton fibre elongation. | 2010 |
|
| Advanced oxidation and reduction process chemistry of methyl tert-butyl ether (MTBE) reaction intermediates in aqueous solution: 2-methoxy-2-methyl-propanal, 2-methoxy-2-methyl-propanol, and 2-methoxy-2-methyl-propanoic acid. | 2009-11 |
|
| Effect of short-time povidone-iodine application on osteoblast proliferation and differentiation. | 2009-10-16 |
|
| Helminth immunoregulation: the role of parasite secreted proteins in modulating host immunity. | 2009-09 |
|
| Optimization of automated large-scale production of [(18)F]fluoroethylcholine for PET prostate cancer imaging. | 2009-07 |
|
| Isolation, identification and expression analysis of salt-induced genes in Suaeda maritima, a natural halophyte, using PCR-based suppression subtractive hybridization. | 2009-06-05 |
|
| Influence of fluorocarbon flat-membrane hydrophobicity on carbon dioxide recovery. | 2009-06 |
|
| 1,4a,7-Trimethyl-7-vinyl-1,2,3,4,4a,4b,5,6,7,8,10,10a-dodeca-hydro-phenanthrene-1-carboxylic acid. | 2009-05-29 |
|
| Cell response to a newly developed Ti-10Ta-10Nb alloy and its sputtered nanoscale coating. | 2009-03 |
|
| Removal characteristics of CO2 using aqueous MEA/AMP solutions in the absorption and regeneration process. | 2009 |
|
| Serotonin increases cilia-driven particle transport via an acetylcholine-independent pathway in the mouse trachea. | 2009 |
|
| Epidemiology and genetic epidemiology of the liver function test proteins. | 2009 |
|
| Bis[N-(2-hydroxy-ethyl)-N-methyl-glycinato]copper(II). | 2008-11-22 |
|
| Biochemical characterization of the initial steps of the Kennedy pathway in Trypanosoma brucei: the ethanolamine and choline kinases. | 2008-10-01 |
|
| 1-Hydroxymethyl-1-methylethan-aminium chloride. | 2008-05-24 |
|
| Influence of additives including amine and hydroxyl groups on aqueous ammonia absorbent for CO2 capture. | 2008-04-10 |
|
| Pharmacokinetics of aminomethylpropanol in rats following oral and a novel dermal study design. | 2008-02 |
|
| Does Litomosoides sigmodontis synthesize dimethylethanolamine from choline? | 2008-01 |
|
| Oxidation of suspected N-nitrosodimethylamine (NDMA) precursors by ferrate (VI): kinetics and effect on the NDMA formation potential of natural waters. | 2008-01 |
|
| Membrane potential controls adipogenic and osteogenic differentiation of mesenchymal stem cells. | 2008 |
|
| Regeneration of 2-amino-2-methyl-1-propanol used for carbon dioxide absorption. | 2008 |
|
| 2-(2-Methoxy-phen-yl)-4,4-dimethyl-4,5-dihydro-1,3-oxazole. | 2007-12-06 |
|
| Adiponectin and AMP kinase activator stimulate proliferation, differentiation, and mineralization of osteoblastic MC3T3-E1 cells. | 2007-11-29 |
|
| [Study of new blended chemical absorbents to absorb CO2]. | 2007-11 |
|
| Evaluation of a method for measuring tissue non-specific alkaline phosphatase activity in healthy subjects. | 2007-11 |
|
| Enhanced enteric properties and stability of shellac films through composite salts formation. | 2007-11 |
|
| Gene profile analysis of osteoblast genes differentially regulated by histone deacetylase inhibitors. | 2007-10-09 |
|
| Proteomic analysis of plasma membrane and secretory vesicles from human neutrophils. | 2007-08-10 |
|
| Micro-morphologic changes around biophysically-stimulated titanium implants in ovariectomized rats. | 2007-07-16 |
|
| Ethanolamine and related amino alcohols increase basal and evoked release of [3H]-D-aspartic acid from synaptosomes by enhancing the filling of synaptic vesicles. | 2007-07-02 |
|
| Oxidation of N-nitrosodimethylamine (NDMA) precursors with ozone and chlorine dioxide: kinetics and effect on NDMA formation potential. | 2007-03-15 |
|
| Synthesis and characterization of a new layered fluoroaluminophosphate (C4H11NOH)3.5[Al4(PO4)5F] x 0.5H3O with extra-large 16-rings. | 2007-01-08 |
|
| Ion exchange preconcentration and separation of mercury species by CE with indirect contactless conductometric detection. | 2006-11 |
|
| Separation of phenolic acids by capillary electrophoresis with indirect contactless conductometric detection. | 2006-04 |
|
| Proinflammatory cytokine responses induced by influenza A (H5N1) viruses in primary human alveolar and bronchial epithelial cells. | 2005-11-11 |
|
| Ion chromatographic analysis of amines, alkanolamines, and associated anions in concrete. | 2005-03 |
|
| Comparative analysis of mouse skeletal muscle fibre type composition and contractile responses to calcium channel blocker. | 2005-02-14 |
|
| Fluorimetric determination of alkaline phosphatase in solid and fluid dairy products. | 2002-04-08 |
Patents
Sample Use Guides
In Vivo Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/17961896
Curator's Comment: rat data
18 mg/kg in water
Route of Administration:
Other
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 17:45:44 GMT 2025
by
admin
on
Mon Mar 31 17:45:44 GMT 2025
|
| Record UNII |
LU49E6626Q
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Systematic Name | English | ||
|
Preferred Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Code | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Brand Name | English | ||
|
Common Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
|
CFR |
21 CFR 176.170
Created by
admin on Mon Mar 31 17:45:44 GMT 2025 , Edited by admin on Mon Mar 31 17:45:44 GMT 2025
|
||
|
EPA PESTICIDE CODE |
5801
Created by
admin on Mon Mar 31 17:45:44 GMT 2025 , Edited by admin on Mon Mar 31 17:45:44 GMT 2025
|
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
441
Created by
admin on Mon Mar 31 17:45:44 GMT 2025 , Edited by admin on Mon Mar 31 17:45:44 GMT 2025
|
PRIMARY | |||
|
LU49E6626Q
Created by
admin on Mon Mar 31 17:45:44 GMT 2025 , Edited by admin on Mon Mar 31 17:45:44 GMT 2025
|
PRIMARY | |||
|
100000153802
Created by
admin on Mon Mar 31 17:45:44 GMT 2025 , Edited by admin on Mon Mar 31 17:45:44 GMT 2025
|
PRIMARY | |||
|
m1716
Created by
admin on Mon Mar 31 17:45:44 GMT 2025 , Edited by admin on Mon Mar 31 17:45:44 GMT 2025
|
PRIMARY | Merck Index | ||
|
11807
Created by
admin on Mon Mar 31 17:45:44 GMT 2025 , Edited by admin on Mon Mar 31 17:45:44 GMT 2025
|
PRIMARY | |||
|
C006551
Created by
admin on Mon Mar 31 17:45:44 GMT 2025 , Edited by admin on Mon Mar 31 17:45:44 GMT 2025
|
PRIMARY | |||
|
124-68-5
Created by
admin on Mon Mar 31 17:45:44 GMT 2025 , Edited by admin on Mon Mar 31 17:45:44 GMT 2025
|
PRIMARY | |||
|
204-709-8
Created by
admin on Mon Mar 31 17:45:44 GMT 2025 , Edited by admin on Mon Mar 31 17:45:44 GMT 2025
|
PRIMARY | |||
|
C77445
Created by
admin on Mon Mar 31 17:45:44 GMT 2025 , Edited by admin on Mon Mar 31 17:45:44 GMT 2025
|
PRIMARY | |||
|
LU49E6626Q
Created by
admin on Mon Mar 31 17:45:44 GMT 2025 , Edited by admin on Mon Mar 31 17:45:44 GMT 2025
|
PRIMARY | |||
|
5606
Created by
admin on Mon Mar 31 17:45:44 GMT 2025 , Edited by admin on Mon Mar 31 17:45:44 GMT 2025
|
PRIMARY | |||
|
SUB128087
Created by
admin on Mon Mar 31 17:45:44 GMT 2025 , Edited by admin on Mon Mar 31 17:45:44 GMT 2025
|
PRIMARY | |||
|
C45678
Created by
admin on Mon Mar 31 17:45:44 GMT 2025 , Edited by admin on Mon Mar 31 17:45:44 GMT 2025
|
CONCEPT | Industrial Aid | ||
|
Aminomethyl propanol
Created by
admin on Mon Mar 31 17:45:44 GMT 2025 , Edited by admin on Mon Mar 31 17:45:44 GMT 2025
|
PRIMARY | |||
|
1310544
Created by
admin on Mon Mar 31 17:45:44 GMT 2025 , Edited by admin on Mon Mar 31 17:45:44 GMT 2025
|
PRIMARY | RxNorm | ||
|
DTXSID8027032
Created by
admin on Mon Mar 31 17:45:44 GMT 2025 , Edited by admin on Mon Mar 31 17:45:44 GMT 2025
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
SALT/SOLVATE -> PARENT | |||
|
|
SALT/SOLVATE -> PARENT | |||
|
|
SALT/SOLVATE -> PARENT |