Details
Stereochemistry | ACHIRAL |
Molecular Formula | C4H11NO |
Molecular Weight | 89.1362 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(C)(N)CO
InChI
InChIKey=CBTVGIZVANVGBH-UHFFFAOYSA-N
InChI=1S/C4H11NO/c1-4(2,5)3-6/h6H,3,5H2,1-2H3
Molecular Formula | C4H11NO |
Molecular Weight | 89.1362 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Aminomethylpropanol is a synthetic ingredient that functions as a buffer to adjust the pH of cosmetics and personal care products. In cosmetics and personal care products, aminomethylpropanol is used in the formulation of creams and lotions, hair sprays, wave sets, hair dyes and colors, eye and facial products, and other hair and skin care products. The main function of aminomethylpropanol in these products is to establish and hold the pH. The Food and Drug Administration (FDA) includes aminomethylpropanol on its list of indirect food additives as a component of adhesives that are in contact with food. The European Chemicals Agency (ECHA) identifies that “substance causes serious eye irritation, is harmful to aquatic life with long lasting effects and causes skin irritation, causes serious eye damage.” Toxicologically significant concentrations of AMP are unlikely to be achieved in the systemic circulation and/or target tissues in humans as a result of dermal application of products containing aminomethylpropanol. Systemically absorbed dose will be rapidly eliminated from the body with little remaining at the application site.
Approval Year
PubMed
Title | Date | PubMed |
---|---|---|
Poly(amide ester)s from 2,6-pyridinedicarboxylic acid and ethanolamine derivatives: identification of macrocycles by matrix-assisted laser desorption/ionization mass spectrometry. | 2002 |
|
Fluorimetric determination of alkaline phosphatase in solid and fluid dairy products. | 2002 Apr 8 |
|
Vascular responsiveness to dimethylaminoethyl methacrylate and its degradation products. | 2003 Jul 1 |
|
Facile syntheses of oxazolines and thiazolines with N-acylbenzotriazoles under microwave irradiation. | 2004 Feb 6 |
|
Determination of carbon dioxide and acid components in exhaust gas by suppressed ion chromatography. | 2004 Jan |
|
Dimethylethanolamine does not prevent liver failure in phosphatidylethanolamine N-methyltransferase-deficient mice fed a choline-deficient diet. | 2004 Mar 22 |
|
Synthesis of levan in water-miscible organic solvents. | 2004 Oct 19 |
|
Rhodovarius lipocyclicus gen. nov. sp. nov., a new genus of the alpha-1 subclass of the Proteobacteria. | 2004 Sep |
|
ATR-FTIR characterization of transport properties of benzoic acid ion-pairs in silicone membranes. | 2004 Sep 28 |
|
Selective disruption of phosphatidylcholine metabolism of the intracellular parasite Toxoplasma gondii arrests its growth. | 2005 Apr 22 |
|
Comparative analysis of mouse skeletal muscle fibre type composition and contractile responses to calcium channel blocker. | 2005 Feb 14 |
|
Ion chromatographic analysis of amines, alkanolamines, and associated anions in concrete. | 2005 Mar |
|
Ion exchange preconcentration and separation of mercury species by CE with indirect contactless conductometric detection. | 2006 Nov |
|
Proteomic analysis of plasma membrane and secretory vesicles from human neutrophils. | 2007 Aug 10 |
|
2-(2-Methoxy-phen-yl)-4,4-dimethyl-4,5-dihydro-1,3-oxazole. | 2007 Dec 6 |
|
[Study of new blended chemical absorbents to absorb CO2]. | 2007 Nov |
|
Evaluation of a method for measuring tissue non-specific alkaline phosphatase activity in healthy subjects. | 2007 Nov |
|
Adiponectin and AMP kinase activator stimulate proliferation, differentiation, and mineralization of osteoblastic MC3T3-E1 cells. | 2007 Nov 29 |
|
Gene profile analysis of osteoblast genes differentially regulated by histone deacetylase inhibitors. | 2007 Oct 9 |
|
Membrane potential controls adipogenic and osteogenic differentiation of mesenchymal stem cells. | 2008 |
|
Regeneration of 2-amino-2-methyl-1-propanol used for carbon dioxide absorption. | 2008 |
|
Influence of additives including amine and hydroxyl groups on aqueous ammonia absorbent for CO2 capture. | 2008 Apr 10 |
|
Pharmacokinetics of aminomethylpropanol in rats following oral and a novel dermal study design. | 2008 Feb |
|
1-Hydroxymethyl-1-methylethan-aminium chloride. | 2008 May 24 |
|
Bis[N-(2-hydroxy-ethyl)-N-methyl-glycinato]copper(II). | 2008 Nov 22 |
|
Biochemical characterization of the initial steps of the Kennedy pathway in Trypanosoma brucei: the ethanolamine and choline kinases. | 2008 Oct 1 |
|
Removal characteristics of CO2 using aqueous MEA/AMP solutions in the absorption and regeneration process. | 2009 |
|
Serotonin increases cilia-driven particle transport via an acetylcholine-independent pathway in the mouse trachea. | 2009 |
|
Epidemiology and genetic epidemiology of the liver function test proteins. | 2009 |
|
Optimization of automated large-scale production of [(18)F]fluoroethylcholine for PET prostate cancer imaging. | 2009 Jul |
|
Influence of fluorocarbon flat-membrane hydrophobicity on carbon dioxide recovery. | 2009 Jun |
|
Isolation, identification and expression analysis of salt-induced genes in Suaeda maritima, a natural halophyte, using PCR-based suppression subtractive hybridization. | 2009 Jun 5 |
|
Cell response to a newly developed Ti-10Ta-10Nb alloy and its sputtered nanoscale coating. | 2009 Mar |
|
1,4a,7-Trimethyl-7-vinyl-1,2,3,4,4a,4b,5,6,7,8,10,10a-dodeca-hydro-phenanthrene-1-carboxylic acid. | 2009 May 29 |
|
Advanced oxidation and reduction process chemistry of methyl tert-butyl ether (MTBE) reaction intermediates in aqueous solution: 2-methoxy-2-methyl-propanal, 2-methoxy-2-methyl-propanol, and 2-methoxy-2-methyl-propanoic acid. | 2009 Nov |
|
Effect of short-time povidone-iodine application on osteoblast proliferation and differentiation. | 2009 Oct 16 |
|
Helminth immunoregulation: the role of parasite secreted proteins in modulating host immunity. | 2009 Sep |
|
Capture of carbon dioxide by amine-impregnated as-synthesized MCM-41. | 2010 |
|
Developmental and molecular physiological evidence for the role of phosphoenolpyruvate carboxylase in rapid cotton fibre elongation. | 2010 |
|
Estrogens attenuate oxidative stress and the differentiation and apoptosis of osteoblasts by DNA-binding-independent actions of the ERalpha. | 2010 Apr |
|
Nucleophilicity and accessibility calculations of alkanolamines: applications to carbon dioxide absorption reactions. | 2010 Dec 16 |
|
Crystal structure and electronic properties of 2-amino-2-methyl-1-propanol (AMP) carbamate. | 2010 Dec 28 |
|
Determination of calcium in synovial fluid samples as an aid to diagnosing osteoarthritis. | 2010 Feb |
|
Association of urinary bisphenol a concentration with heart disease: evidence from NHANES 2003/06. | 2010 Jan 13 |
|
Effects of shape, porosity, and operating parameters on carbon dioxide recovery in polytetrafluoroethylene membranes. | 2010 Jul 15 |
|
Intranasal delivery of influenza subunit vaccine formulated with GEM particles as an adjuvant. | 2010 Jun |
|
Harmonization of values for serum alkaline phosphatase catalytic activity concentration employing commutable calibration materials. | 2010 Jun 3 |
|
Evaluation of alkanolamine solutions for carbon dioxide removal in cross-flow rotating packed beds. | 2010 Mar 15 |
|
N-(2-Hy-droxy-1,1-dimethyl-eth-yl)-benzene-sulfonamide. | 2010 Oct 31 |
|
Distinguishing between maternally-mediated and directly embryotoxic modes-of-action for postimplantation loss induced in rats by 2-amino-2-methylpropanol. | 2014 Nov |
Patents
Sample Use Guides
In Vivo Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/17961896
Curator's Comment: rat data
18 mg/kg in water
Route of Administration:
Other
Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 15:04:53 GMT 2023
by
admin
on
Fri Dec 15 15:04:53 GMT 2023
|
Record UNII |
LU49E6626Q
|
Record Status |
Validated (UNII)
|
Record Version |
|
-
Download
Name | Type | Language | ||
---|---|---|---|---|
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Code | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Official Name | English | ||
|
Brand Name | English | ||
|
Common Name | English |
Classification Tree | Code System | Code | ||
---|---|---|---|---|
|
CFR |
21 CFR 176.170
Created by
admin on Fri Dec 15 15:04:53 GMT 2023 , Edited by admin on Fri Dec 15 15:04:53 GMT 2023
|
||
|
EPA PESTICIDE CODE |
5801
Created by
admin on Fri Dec 15 15:04:53 GMT 2023 , Edited by admin on Fri Dec 15 15:04:53 GMT 2023
|
Code System | Code | Type | Description | ||
---|---|---|---|---|---|
|
441
Created by
admin on Fri Dec 15 15:04:53 GMT 2023 , Edited by admin on Fri Dec 15 15:04:53 GMT 2023
|
PRIMARY | |||
|
LU49E6626Q
Created by
admin on Fri Dec 15 15:04:53 GMT 2023 , Edited by admin on Fri Dec 15 15:04:53 GMT 2023
|
PRIMARY | |||
|
100000153802
Created by
admin on Fri Dec 15 15:04:53 GMT 2023 , Edited by admin on Fri Dec 15 15:04:53 GMT 2023
|
PRIMARY | |||
|
m1716
Created by
admin on Fri Dec 15 15:04:53 GMT 2023 , Edited by admin on Fri Dec 15 15:04:53 GMT 2023
|
PRIMARY | Merck Index | ||
|
11807
Created by
admin on Fri Dec 15 15:04:53 GMT 2023 , Edited by admin on Fri Dec 15 15:04:53 GMT 2023
|
PRIMARY | |||
|
C006551
Created by
admin on Fri Dec 15 15:04:53 GMT 2023 , Edited by admin on Fri Dec 15 15:04:53 GMT 2023
|
PRIMARY | |||
|
124-68-5
Created by
admin on Fri Dec 15 15:04:53 GMT 2023 , Edited by admin on Fri Dec 15 15:04:53 GMT 2023
|
PRIMARY | |||
|
204-709-8
Created by
admin on Fri Dec 15 15:04:53 GMT 2023 , Edited by admin on Fri Dec 15 15:04:53 GMT 2023
|
PRIMARY | |||
|
C77445
Created by
admin on Fri Dec 15 15:04:53 GMT 2023 , Edited by admin on Fri Dec 15 15:04:53 GMT 2023
|
PRIMARY | |||
|
LU49E6626Q
Created by
admin on Fri Dec 15 15:04:53 GMT 2023 , Edited by admin on Fri Dec 15 15:04:53 GMT 2023
|
PRIMARY | |||
|
5606
Created by
admin on Fri Dec 15 15:04:53 GMT 2023 , Edited by admin on Fri Dec 15 15:04:53 GMT 2023
|
PRIMARY | |||
|
SUB128087
Created by
admin on Fri Dec 15 15:04:53 GMT 2023 , Edited by admin on Fri Dec 15 15:04:53 GMT 2023
|
PRIMARY | |||
|
C45678
Created by
admin on Fri Dec 15 15:04:53 GMT 2023 , Edited by admin on Fri Dec 15 15:04:53 GMT 2023
|
CONCEPT | Industrial Aid | ||
|
Aminomethyl propanol
Created by
admin on Fri Dec 15 15:04:53 GMT 2023 , Edited by admin on Fri Dec 15 15:04:53 GMT 2023
|
PRIMARY | |||
|
1310544
Created by
admin on Fri Dec 15 15:04:53 GMT 2023 , Edited by admin on Fri Dec 15 15:04:53 GMT 2023
|
PRIMARY | RxNorm | ||
|
DTXSID8027032
Created by
admin on Fri Dec 15 15:04:53 GMT 2023 , Edited by admin on Fri Dec 15 15:04:53 GMT 2023
|
PRIMARY |
Related Record | Type | Details | ||
---|---|---|---|---|
|
SALT/SOLVATE -> PARENT | |||
|
SALT/SOLVATE -> PARENT | |||
|
SALT/SOLVATE -> PARENT |