Details
Stereochemistry | ACHIRAL |
Molecular Formula | C6H10O4 |
Molecular Weight | 146.1412 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(=O)CCCCC(O)=O
InChI
InChIKey=WNLRTRBMVRJNCN-UHFFFAOYSA-N
InChI=1S/C6H10O4/c7-5(8)3-1-2-4-6(9)10/h1-4H2,(H,7,8)(H,9,10)
Molecular Formula | C6H10O4 |
Molecular Weight | 146.1412 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
DescriptionSources: https://www.thechemco.com/chemical/adipic-acid/
Sources: https://www.thechemco.com/chemical/adipic-acid/
Adipic acid has been incorporated into controlled-release formulation matrix tablets to obtain a pH-independent release for both weakly basic and weakly acidic drugs. It has also been incorporated into the polymeric coating of hydrophilic monolithic systems to modulate the intragel pH, resulting in zero-order release of hydrophilic drugs. The disintegration at intestinal pH of the enteric polymer shellac has been reported to improve when adipic acid was used as a pore-forming agent without affecting release in the acidic media. Adipic acid is used to make bisobrin an antifibrinolytic.
Approval Year
PubMed
Title | Date | PubMed |
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Organic acids in aqueous humour and plasma: post mortem study in infants and diagnosis of enzymopathies. | 1991 |
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Characterization of a microorganism isolated from the effluent of hydrogen fermentation by microflora. | 2001 |
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Identification and quantitation of extractables from cellulose acetate butyrate (CAB) and estimation of their in vivo exposure levels. | 2004 Jun 29 |
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Supramolecular aggregates between carboxylate anions and an octaaza macrocyclic receptor. | 2004 Oct 21 |
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catena-Poly[[aquabis(1H-benzimidazole-kappa N3)manganese(II)]-mu-adipato]. | 2005 Apr |
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Conversion of food waste into hydrogen by thermophilic acidogenesis. | 2005 Feb |
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X-ray studies on crystalline complexes involving amino acids and peptides. XLII. Adipic acid complexes of L- and DL-arginine and supramolecular association in arginine-dicarboxylic acid complexes. | 2005 Feb |
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Cellulose acetate butyrate microcapsules containing dextran ion-exchange resins as self-propelled drug release system. | 2005 Jul |
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Templated metal-organic frameworks: synthesis, structures, thermal properties and solid-state transformation of two novel calcium-adipate frameworks. | 2005 Jun 21 |
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Alkane oxidation by osmium tetroxide. | 2005 Mar 9 |
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Preparation and in vitro evaluation of propylthiouracil microspheres made of Eudragit RL 100 and cellulose acetate butyrate polymers using the emulsion-solvent evaporation method. | 2005 May |
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Functional characterization of high-affinity Na(+)/dicarboxylate cotransporter found in Xenopus laevis kidney and heart. | 2005 Nov |
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Uniaxial drawing of poly[(R)-3-hydroxybutyrate]/cellulose acetate butyrate blends and their orientation behavior. | 2005 Sep 16 |
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Amended final report of the safety assessment of dibutyl adipate as used in cosmetics. | 2006 |
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Matrix-assisted laser desorption/ionization time-of-flight/time-of-flight tandem mass spectra of poly(butylene adipate). | 2006 |
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Crystal engineering of analogous and homologous organic compounds: hydrogen bonding patterns in trimethoprim hydrogen phthalate and trimethoprim hydrogen adipate. | 2006 Apr 7 |
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Changes in bacterial community during fermentative hydrogen and acid production from organic waste by thermophilic anaerobic microflora. | 2006 Aug |
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Enhancement of the Curie temperature by isomerization of diarylethene (DAE) for an organic-inorganic hybrid system: Co4(OH)7(DAE)0.5.3H2O. | 2006 Dec 11 |
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Ala-504 is a determinant of substrate binding affinity in the mouse Na(+)/dicarboxylate cotransporter. | 2006 Jun |
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Modulatory effects of chitosan adipate on the T and B lymphocyte subsets in mice. | 2006 Jun |
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Modelling calcium carbonate biomineralisation processes. | 2006 May |
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Porous structures of polymer films prepared by spin coating with mixed solvents under humid condition. | 2006 May 9 |
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Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods. | 2006 Nov |
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[Physical, chemical and biological properties of food modified starches]. | 2007 |
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Molecular model for host–guest interaction of tetraamino-tert-butylthiacalix[4]arene and tetraamino-tert-butylcalix[4]arene receptors with carboxylate and dicarboxylate guests: an ONIOM study. | 2007 |
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Cellulose acetate butyrate-pH/thermosensitive polymer microcapsules containing aminated poly(vinyl alcohol) microspheres for oral administration of DNA. | 2007 Apr |
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Genome analysis of Minibacterium massiliensis highlights the convergent evolution of water-living bacteria. | 2007 Aug |
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Adipic and malonic acid aqueous solutions: surface tensions and saturation vapor pressures. | 2007 Dec 20 |
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Fluxome analysis using GC-MS. | 2007 Feb 7 |
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A novel multicompartimental system based on aminated poly(vinyl alcohol) microspheres/succinoylated pullulan microspheres for oral delivery of anionic drugs. | 2007 Feb 7 |
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The relationship between instability of H2 production and compositions of bacterial communities within a dark fermentation fluidized-bed bioreactor. | 2007 Jul 1 |
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Host-guest adaptability within oxothiomolybdenum wheels: structures, studies in solution and DFT calculations. | 2007 Jul 28 |
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Magnetic resonance imaging findings of adult-onset glutaric aciduria type I. | 2007 Jun |
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Synthesis and characterization of branched polymers from lipase-catalyzed trimethylolpropane copolymerizations. | 2007 Jun |
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Effect of the dispersion of Eudragit S100 powder on the properties of cellulose acetate butyrate microspheres containing theophylline made by the emulsion-solvent evaporation method. | 2007 May |
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Exploring lanthanide luminescence in metal-organic frameworks: synthesis, structure, and guest-sensitized luminescence of a mixed europium/terbium-adipate framework and a terbium-adipate framework. | 2007 May 14 |
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[(3)H]Adenine is a suitable radioligand for the labeling of G protein-coupled adenine receptors but shows high affinity to bacterial contaminations in buffer solutions. | 2007 Sep |
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Diverse entangled metal-organic framework materials incorporating kinked organodiimine and flexible aliphatic dicarboxylate ligands: synthesis, structure, physical properties, and reversible structural reorganization. | 2007 Sep 3 |
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Preparation and characterization of hydroxyapatite/poly(ethylene adipate) hybrid composites. | 2008 |
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Organic acid concentrations in amniotic fluid found in normal and Down syndrome pregnancies. | 2008 |
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Chemical modification of zinc hydroxide nitrate and Zn-Al-layered double hydroxide with dicarboxylic acids. | 2008 Apr 1 |
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Prenatal phenol and phthalate exposures and birth outcomes. | 2008 Aug |
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Determination of insulin in innovative formulations by means of LC coupled to fluorescence detection. | 2008 Dec 15 |
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Compatibility study of trans-1,4,5,8-tetranitro-1,4,5,8-tetraazadecalin (TNAD) with some energetic components and inert materials. | 2008 Dec 30 |
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Diclofenac sodium loaded-cellulose acetate butyrate: effect of processing variables on microparticles properties, drug release kinetics and ulcerogenic activity. | 2008 Feb |
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Ketotifen controlled release from cellulose acetate propionate and cellulose acetate butyrate membranes. | 2008 Feb |
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Determination of phthalates and adipate in bottled water by headspace solid-phase microextraction and gas chromatography/mass spectrometry. | 2008 Jan 18 |
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Proteomic investigation of amino acid catabolism in the indigenous gut anaerobe Fusobacterium varium. | 2008 Jul |
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Development of a liposaccharide-based delivery system and its application to the design of group A streptococcal vaccines. | 2008 Mar 13 |
|
Release profile comparison and stability of diltiazem-resin microcapsules in sustained release suspensions. | 2008 Mar 20 |
Patents
Substance Class |
Chemical
Created
by
admin
on
Edited
Wed Jul 05 22:36:54 UTC 2023
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Record UNII |
76A0JE0FKJ
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CFR |
21 CFR 184.1009
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JECFA EVALUATION |
ADIPIC ACID
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JECFA EVALUATION |
INS-355
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ADIPIC ACID
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C45678
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