U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 6691 - 6700 of 13501 results

Status:
Investigational
Source:
INN:erocainide
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
INN:erizepine [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Erizepine is a compound with neuroleptic activity. Erizepine is considered to bind dopamine receptors.
Status:
Investigational
Source:
INN:furfenorex
Source URL:

Class (Stereo):
CHEMICAL (UNKNOWN)

Conditions:

Furfenorex (unde brand name Frugalan), was used against obesity as an appetite suppressant. One of its metabolite was metamphetamine, which lead to the abuse to the drug. That is why this drug is no longer marketed
Status:
Investigational
Source:
INN:furbucillin
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Furbucillin is a synthetic antibacterial agent that has never been marketed. Information about the current use of this drug is not available.
Status:
Investigational
Source:
INN:furnidipine
Source URL:

Class (Stereo):
CHEMICAL (MIXED)

Furnidipine, a calcium channel blocker was developed as an antihypertensive agent. It participated in clinical trials for the treatment of patients with heart failure, hypertension, and ischemic heart disorders in Spain and in Switzerland. However, all these studies were discontinued.
Status:
Investigational
Source:
INN:furmethoxadone
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Furmethoxadone was developed as an antibacterial agent and was studied as an anthelmintic. Information about the current use of this compound is not available.
Status:
Investigational
Source:
INN:furofenac
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)


Furofenac (also known as SAS 650), a drug that has antiplatelet-aggregation activity and anti-inflammatory activity combined with low ulcerogenic power. It was shown that the furofenac mechanism of action involved the modulation of the platelet cyclooxygenase pathway.
Status:
Investigational
Source:
USAN:FLUPREDNISOLONE VALERATE [USAN]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Conditions:

The information related to the biological or pharmacological application of fluprednisolone valerate is absent.
Status:
Investigational
Source:
INN:trifenagrel
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


Trifenagrel is a potent inhibitor of arachidonate (AA)- and collagen-induced aggregation of platelets from several animal species and humans. When trifenagrel was administered p.o. to guinea pigs, there was a sustained (greater than 3 hr) inhibition of AA- and collagen-induced platelet aggregation ex vivo. In humans, trifenagrel inhibited the second phase of ADP-induced aggregation ex vivo up to 6 hr after a single dose of 100 to 300 mg p.o. The mechanism of action of trifenagrel appears to be a reversible inhibition of platelet AA cyclooxygenase. Although trifenagrel caused gastrointestinal irritation in dogs and humans, the nature of the damage suggests that the compound may have acted as a local irritant in these species. Furthermore, compared to aspirin trifenagrel produced significantly less gastric irritation and fecal blood loss in humans. Trifenagrel was developed for the treatment of ischemic heart disorders. However, this development was discontinued.
Status:
Investigational
Source:
INN:trocimine [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Trocimine (N-3,4,5-trimethoxybenzoylheptamethylenimine) is heptamethylenimine derivative with antidepressant activity.

Showing 6691 - 6700 of 13501 results