FURFENOREX

Details

Stereochemistry	UNKNOWN
Molecular Formula	C15H19NO
Molecular Weight	229.3175
Optical Activity	( + )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(CC1=CC=CC=C1)N(C)CC2=CC=CO2

InChI

InChIKey=DLGIIZAHQPTVCJ-UHFFFAOYSA-N

InChI=1S/C15H19NO/c1-13(11-14-7-4-3-5-8-14)16(2)12-15-9-6-10-17-15/h3-10,13H,11-12H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C15H19NO
Molecular Weight	229.3175
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/5084766 | https://www.ncbi.nlm.nih.gov/pubmed/5611635

Furfenorex (unde brand name Frugalan), was used against obesity as an appetite suppressant. One of its metabolite was metamphetamine, which lead to the abuse to the drug. That is why this drug is no longer marketed

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Obesity 203 Sources: https://www.ncbi.nlm.nih.gov/pubmed/5611635	Primary		Not Provided 504	FRUGALAN Approved Use Unknown

PubMed

Title	Date	PubMed
[Pharmacologic study of an anorexigenic agent: furfenorex].	1967 May	6035092
[Clinical study of a new anorexigen: E-106-E (Frugalan Diamant)].	1967 May 28	5611635
Toxicokinetics of amphetamines: metabolism and toxicokinetic data of designer drugs, amphetamine, methamphetamine, and their N-alkyl derivatives.	2002 Apr	11897973
Precursor medications as a source of methamphetamine and/or amphetamine positive drug testing results.	2002 May	12024689

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:36:09 GMT 2023` Edited by `admin` on `Fri Dec 15 15:36:09 GMT 2023`
Record UNII	X83CZ0Y5TF
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

FURFENOREX

Official Name

English

D-FURFENOREX

Common Name

English

furfenorex [INN]

Common Name

English

SD 27115 FREE BASE

Code

English

2-FURANMETHANAMINE, N-METHYL-N-(1-METHYL-2-PHENYLETHYL)-, (+)-

Systematic Name

English

S-(+)-N-METHYL-N-(.ALPHA.-METHYLPHENETHYL)FURFURYLAMINE

Systematic Name

English

FURFENOREX, (+)-

Common Name

English

FURFENOREX [MART.]

Common Name

English

FURFURYLMETHYLAMPHETAMINE D-FORM [MI]

Common Name

English

FURFURYLMETHYLAMPHETAMINE D-FORM

Common Name

English

D-FURFURYLMETHYLAMPHETAMINE

Common Name

English

SD-27115 FREE BASE

Code

English

(+)-N-METHYL-N-(.ALPHA.-METHYLPHENETHYL)FURFURYLAMINE

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29728