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Showing 1 - 10 of 28 results

Status:
US Approved Rx (2013)
First approved in 2013

Class (Stereo):
CHEMICAL (ABSOLUTE)



Luliconazole (trade names Luzu, Lulicon) is an imidazole antifungal drug. As a 1% topical cream, It is indicated for the treatment of athlete's foot, jock itch, and ringworm caused by dermatophytes such as Trichophyton rubrum, Microsporum gypseum and...
Status:
US Approved Rx (2016)
First approved in 1988

Class (Stereo):
CHEMICAL (ACHIRAL)



Oxiconazole nitrate is 2',4'-dichloro-2-imidazol-1-ylacetophenone (Z)-[0-(2,4-dichlorobenzyl)oxime], mononitrate is an imidazole derivative characterized by a broad fungistatic spectrum. In vitro oxiconazole is highly effective against many dermato...
Status:
US Approved Rx (1988)
First approved in 1988

Class (Stereo):
CHEMICAL (ACHIRAL)



Naftifine is a synthetic, broad spectrum, antifungal agent and allylamine derivative. The following in vitro data are available, but their clinical significance is unknown. Naftifine has been shown to exhibit fungicidal activity in vitro against a br...
Status:
US Approved Rx (2013)
First approved in 1982

Class (Stereo):
CHEMICAL (RACEMIC)


Conditions:

Econazole (commonly used as the nitrate salt) is an antifungal medication of the imidazole class. It is a broad spectrum antimycotic with some action against Gram positive bacteria. It is used topically in dermatomycoses also orally and parenterally....
Status:
US Approved Rx (2000)
First approved in 1981

Class (Stereo):
CHEMICAL (RACEMIC)



2S,4R ketoconazole or levoketoconazole is the 2S,4R enantiomer of ketoconazole, purified from racemic ketoconazole. Both enantiomers exerts antifungal activity. Ketoconazole activates AhR in gene reporter cell line and dose-dependently induces CYP1A1...
Status:
US Approved Rx (2016)
First marketed in 1921

Class (Stereo):
CHEMICAL (ACHIRAL)



Benzoic acid is a natural ingredient occurring in many foodstuffs and in plant extracts. Benzoic acid, its salts and esters are used as preservatives in cosmetic products, with a maximum concentration of 0.5 %. Benzoic acid and sodium benzoate are on...
Status:
US Approved OTC
First approved in 1975

Class (Stereo):
CHEMICAL (ACHIRAL)



Clotrimazole is an anti-fungal medicine indicated for the treatment of vaginal yeast infections and tinea. It can be used either in combination with other drugs (betamethasone dipropionate) or alone, in form of topical or vaginal cream. The drug exer...
Status:
US Approved OTC
First approved in 1971

Class (Stereo):
CHEMICAL (ACHIRAL)


Haloprogin is an active synthetic antifungal and antimonilial agent that was effective in the treatment of superficial fungal and monilial infections of the skin. Because of these two basic therapeutic effects, haloprogin was especially useful in the...
Status:
US Approved OTC
First approved in 1965

Class (Stereo):
CHEMICAL (ACHIRAL)



Tolnaftate is a thiocarbamate derivative used as an over-the-counter anti-fungal agent for treatment of athlete's foot and ringworm. Tolnaftate acts by inhibition of ergosterol biosynthesis pathway in fungal cells.
Status:
US Approved OTC
First approved in 1945

Class (Stereo):
CHEMICAL (ACHIRAL)



Undecylenic acid is unsaturated fatty acid, which naturally occurs in sweat, and is commercially produced by the vacuum distillation of castor bean oil. It is recognized as GRASE by FDA, and is marketed over the counter to treat skin infections and t...