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Showing 1 - 10 of 64 results

Status:
US Approved Rx (2006)
First approved in 2006

Class (Stereo):
CHEMICAL (ABSOLUTE)



Ciclesonide is a glucocorticoid receptor agonist indicated for the treatment of allergic rhinitis (Omnaris nasal spray) and asthma (Alvesco). It was also developed by Byk Gulden for chronic obstructive pulmonary disease (COPD), but no development had...
Status:
US Approved Rx (2011)
First approved in 2001

Class (Stereo):
CHEMICAL (ACHIRAL)



Desloratadine is an active, descarboethoxy metabolite of loratadine. It acts by selective inhibition of H1 histamine receptor and thus provides relief to patients with allergic rhinitis and chronic idiopathic urticaria. Desloratadine was approved by ...
Status:
US Approved Rx (2015)
First approved in 1998

Class (Stereo):
CHEMICAL (ABSOLUTE)



Montelukast (SINGULAIR®) is a selective and orally active leukotriene D4 (LTD4) receptor antagonist that inhibits the cysteinyl leukotriene CysLT1 receptor. It is indicated for the prophylaxis and chronic treatment of asthma, for prevention of exerci...
Status:
US Approved Rx (2012)
First approved in 1996

Class (Stereo):
CHEMICAL (RACEMIC)



Fexofenadine is a second-generation, long lasting H1-receptor antagonist (antihistamine) which has a selective and peripheral H1-antagonist action. Histamine is a chemical that causes many of the signs that are part of allergic reactions, such as the...
Status:
US Approved Rx (2017)
First approved in 1996

Class (Stereo):
CHEMICAL (RACEMIC)



Azelastine, a phthalazine derivative, is an antihistamine and mast cell stabilizer. Azelastine is oxidatively metabolized to the principal active metabolite, desmethylazelastine, by the cytochrome P450 enzyme system. It is indicated for the relief of...
Status:
US Approved Rx (2015)
First approved in 1996

Class (Stereo):
CHEMICAL (ACHIRAL)



Olopatadine is an antihistamine (as well as anticholinergic and mast cell stabilizer) used to treat itching associated with allergic conjunctivitis (eye allergies). Olopatadine is a selective histamine H1 antagonist that binds to the histamine H1 rec...
Status:
US Approved Rx (2013)
First approved in 1995

Class (Stereo):
CHEMICAL (ABSOLUTE)



Levocetirizine is the active enantiomer of cetirizine. It is inverse agonist of H1 receptors. Levocetirizine hydrochloride was approved for treatment of Allergic Rhinitis and Chronic Idiopathic Urticaria.
Status:
US Approved Rx (2018)
First approved in 1988

Class (Stereo):
CHEMICAL (RACEMIC)



Cetirizine, a human metabolite of hydroxyzine, is an antihistamine; its principal effects are mediated via selective inhibition of peripheral H1 receptors. It is indicated for the relief of nasal and non-nasal symptoms associated with seasonal or per...
Status:
US Approved Rx (2006)
First approved in 1961

Class (Stereo):
CHEMICAL (ACHIRAL)



Cyproheptadine hydrochloride anhydrous is a first-generation antihistamine with additional anticholinergic, antiserotonergic, and local anesthetic properties. It is indicted for the treatment of perennial and seasonal allergic rhinitis; vasomotor rhi...
Status:
US Approved Rx (2017)
First approved in 1958

Class (Stereo):
CHEMICAL (ABSOLUTE)


Triamcinolone acetonide is a synthetic corticosteroid used to treat various skin conditions, and to relieve the discomfort of mouth sores. In nasal spray form, it is used to treat allergic rhinitis. It is a more potent derivative of triamcinolone, a...