Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Ixazomib (trade name Ninlaro) is a drug for the treatment of multiple myeloma in adults after at least one prior therapy, in combination with lenalidomide and dexamethasone. It is taken by mouth in form of capsules. Common side effects include diarrh...
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Valrubicin is a semisynthetic analog of the anthracycline doxorubicin, and is administered by infusion directly into the bladder. Valrubicin is an anthracycline that affects a variety of inter-related biological functions, most of which involve nucle...
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Fluazuron (N-[[4-chloro-3-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxyphenyl]carbamoyl]-2,6-difluorobenzamide, trade name Acatak) is an insect growth regulator belonging to the class of benzoyl phenyl urea derivatives, a class of chitin synthesis in...
Class (Stereo):
CHEMICAL (ACHIRAL)
MLN8054 is a reversible, ATP competitive inhibitor of recombinant Aurora A, developed by Millennium Pharmaceuticals. MLN8054 was tested in phase I clinical trials against advanced solid tumors. Reversible somnolence probably due to off-target inhibit...
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Fenretinide (4-HPR) is an orally-active synthetic phenylretinamide analogue of retinol (vitamin A) with potential antineoplastic and chemopreventive activities. Fenretinide binds to and activates retinoic acid receptors (RARs), thereby inducing cell ...
Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
Sinigrin is a glucosinolate that is found in plants of the Brassicaceae family. It is enzymatically degraded to allyl isothiocyanate which is responsible for the taste of mustard and horseradish. Allyl isothiocyanate has been identified as having a...
Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Yangonin is a natural kavalactone found in the kava plant. Yangonin has been shown to possess binding affinity for the cannabinoid receptor CB1, where it behaves as an agonist. Yangonin also inhibits anchorage-dependent and independent growth of blad...
Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Piperlongumine is a natural bioactive small molecule isolated from the Piper longum Linn plant. This compound is easily available, inexpensive, and has therapeutic effects against cancer, heart disease, intestinal diseases, diabetes, obesity, joint p...
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Evans Blue (EBD) is an azo dye which has a very high affinity for serum albumin. It can be useful in physiology in estimating the proportion of body water contained in blood plasma. Evans Blue Dye is widely used to study blood vessel and cellular mem...
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
Aceglatone (Glucaron/ 2.5-Di-O-acetyl-D-glucaro-1,4:6,3-dilactone/ DAGDL ) is a non-toxic natural inhibitor of beta-glucuronidase. Is an antineoplastic drug available in Japan, which is used for preventive therapy after preservative operation against...