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Showing 1 - 10 of 150 results

Status:
US Approved Rx (2006)
First approved in 2000

Class (Stereo):
CHEMICAL (ACHIRAL)



Meloxicam (brand name Mobic) is an nonsteroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. Mobic is indicated for the relief of the signs and symptoms of osteoarthritis and rheumatoid arthritis, and has been available i...
Status:
US Approved Rx (2003)
First approved in 1992

Class (Stereo):
CHEMICAL (RACEMIC)



Sotalol has both beta-adrenoreceptor blocking and cardiac action potential duration prolongation antiarrhythmic properties. Sotalol inhibits response to adrenergic stimuli by competitively blocking β1-adrenergic receptors within the myocardium and β2...
Status:
US Approved Rx (2019)
First approved in 1992

Class (Stereo):
CHEMICAL (ABSOLUTE)



Rifabutin is an antibiotic that inhibits DNA-dependent RNA polymerase activity in susceptible cells. Specifically, it interacts with bacterial RNA polymerase but does not inhibit the mammalian enzyme. It is bactericidal and has a very broad spectrum ...
Status:
US Approved Rx (2012)
First approved in 1991

Class (Stereo):
CHEMICAL (ACHIRAL)



Fumazenil is an imidazobenzodiazepine derivative and a potent benzodiazepine receptor antagonist that competitively inhibits the activity at the benzodiazepine recognition site on the GABA/benzodiazepine receptor complex, thereby reversing the effect...
Status:
US Approved Rx (1993)
First approved in 1986

Class (Stereo):
CHEMICAL (ABSOLUTE)



Dexketoprofen is a nonsteroidal anti-inflammatory drug (NSAID), manufactured by Menarini under the tradename Keral. Dexketoprofen is indicated for short-term treatment of mild to moderate pain, including dysmenorrhoea. Dexketoprofen works by blockin...
Status:
US Approved Rx (2021)
First approved in 1986

Class (Stereo):
CHEMICAL (ABSOLUTE)



Cefixime, an antibiotic, is a third-generation cephalosporin like ceftriaxone and cefotaxime. Cefixime is highly stable in the presence of beta-lactamase enzymes. As a result, many organisms resistant to penicillins and some cephalosporins due to the...
Status:
US Approved Rx (2023)
First approved in 1964

Class (Stereo):
CHEMICAL (ABSOLUTE)

Targets:


Melphalan, also known as L-phenylalanine mustard, phenylalanine mustard, L-PAM, or L-sarcolysin, is a phenylalanine derivative of nitrogen mustard. Melphalan is a bifunctional alkylating agent which produces a number of DNA adducts with the DNA inter...
Status:
US Approved Rx (2019)
First approved in 1959

Class (Stereo):
CHEMICAL (MIXED)

Targets:


Cyclophosphamide (the generic name for Cytoxan, Neosar, Revimmune), also known as cytophosphane, is a nitrogen mustard alkylating agent, from the oxazophorines group. It is used to treat various types of cancer and some autoimmune disorders. It is a ...
Status:
US Approved Rx (2022)
First approved in 1953

Class (Stereo):
CHEMICAL (ACHIRAL)



Pyrimethamine, sold under the trade name Daraprim, is one of the folic acid antagonists that is used as an antimalarial or with a sulfonamide to treat toxoplasmosis. In addition it was approved in Chemoprophylaxis of Malaria. However, resistance to p...
Status:
US Approved OTC
First approved in 1961

Class (Stereo):
CHEMICAL (RACEMIC)

Conditions:

Racephedrine in combination with theophylline, phenobarbital was used to treat bronchial asthma. However, its application was substituted more effective agent. In addition, FDA has reviewed the final monograph for over-the-counter bronchodilator drug...